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NCT05891171 · ClinicalTrials.gov registry record · Phase 1
Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers
A Phase 1 study of Ovarian Cancer and Bladder Cancer, sponsored by Arcus Biosciences.
- Active
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 15
- Study locations
NCT05891171: Active Phase 1 study of Ovarian Cancer and Bladder Cancer, sponsored by Arcus Biosciences.
NCT05891171 is a Phase 1 study of Ovarian Cancer and Bladder Cancer that is active but no longer recruiting, run by Arcus Biosciences. The registered enrollment target is 40 participants, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (95% lower). The trial reports 15 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05891171, a Phase 1 study of Ovarian Cancer and Bladder Cancer, is active but no longer recruiting, sponsored by Arcus Biosciences.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 15
- Study locations
Study Summary
The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.
Conditions Studied
Interventions
- DRUG Fluorouracil
- DRUG Leucovorin
- DRUG Oxaliplatin
- DRUG Zimberelimab
- DRUG AB598
Study Locations (15)
Other
- Adelaide Cancer Research - Adelaide
- Queen Elizabeth Hospital - Adelaide
- National Cheng Kung University Hospital - Tainan
- Taipei Veterans General Hospital - Taipei
Florida
- Mayo Clinic Florida - Jacksonville
- Lake City Cancer Care, LLC. - Lake City
Ohio
- Gabrail Cancer Center (GCC) Canton Facility - Canton
- University Hospitals Cleveland Medical Center - Cleveland
Arizona
- Mayo Clinic Arizona - Phoenix
Illinois
- Affinity Health Hope and Healing Cancer Services, LLC - Hinsdale
Michigan
- Karmanos Cancer Institute - Detroit
Minnesota
- Mayo Clinic Rochester - Rochester
New Jersey
- Rutgers Cancer Institute of New Jersey - New Brunswick
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2023-10-13 |
| Est. Completion | 2026-03 |
| Phase | Phase 1 |
What the registry record for NCT05891171 still lists
NCT05891171 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 729-participant average among 322 other Ovarian Cancer trials with a reported enrollment target (95% lower).
The record links to 10 conditions, with Ovarian Cancer appearing as the primary indexed condition, and to 5 interventions - of which Fluorouracil is the first listed.
NCT05891171 lists 15 locations in 10 states (Other, Florida, Ohio).
Frequently Asked Questions
What is clinical trial NCT05891171 about?
NCT05891171 is a clinical study titled "Study of AB598 Monotherapy and Combination Therapy in Participants With Advanced Cancers". The primary purpose of this study is to assess the safety and tolerability of AB598 in participants with advanced malignancies.
What is the current status of trial NCT05891171?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2023-10-13. Estimated completion is 2026-03.
What conditions does trial NCT05891171 study?
This clinical trial studies the following conditions: Ovarian Cancer, Bladder Cancer, Gastric Cancer, Cervical Cancer, Esophageal Cancer.
What interventions are being tested in trial NCT05891171?
The interventions under investigation include: Fluorouracil (DRUG), Leucovorin (DRUG), Oxaliplatin (DRUG), Zimberelimab (DRUG), AB598 (DRUG).
Who is sponsoring clinical trial NCT05891171?
This trial is sponsored by Arcus Biosciences, which has 25 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05891171 being conducted?
This trial has 15 study locations across Arizona, Florida, Illinois, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ovarian Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05891171's enrollment target sits among peer trials
40 227th of 322 higher than 92 of 322 other Ovarian Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ovarian Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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