Abramson Cancer Center at Penn Medicine

332 total trials 236 currently recruiting 52 completed

Trial Pipeline

RECRUITING NA

Comparing Numbing Techniques in Mohs Micrographic Surgery

NCT07222241

RECRUITING NA

Photobiomodulation in Head and Neck Cancer-Related Chronic Lymphedema

NCT06837480

RECRUITING NA

Catalyzing Cigarette Smoking Cessation Through Harm Reduction Sampling Among People Unmotivated to Quit

NCT07199517

RECRUITING NA

The Erector Spinae Plane Block For Gastrointestinal Malignancy Pain Treatment (EGIPT)

NCT07211386

RECRUITING

Safe and Explainable AI

NCT06694181

RECRUITING Early Phase 1

CYTALUX for Intraoperative Imaging of Patients With Endometrial Cancer

NCT07278986

RECRUITING Phase 1

FTT PET/CT in Pancreatic Neuroendocrine Tumors

NCT07114939

RECRUITING Phase 2

Pembrolizumab and Odetiglucan in Liver Predominant Metastatic Colorectal Adenocarcinoma

NCT07082439

RECRUITING

Vape Use Among Younger & Older Smokers

NCT07214168

RECRUITING

Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)

NCT07471958

RECRUITING NA

Telehealth Collaborative Care Model (CoCM) in Lung Cancer

NCT07102147

RECRUITING

Practical Geriatric Assessment (PGA) Implementation Strategies and Correlative Evaluations (PACE-70)

NCT06870617

RECRUITING Phase 2

Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

NCT06747845

RECRUITING Early Phase 1

Multitracer [18F]Fluciclovine and 18F-FDG PET, and Advanced MRI for Metabolic Profiling of Glioblastoma

NCT06613841

RECRUITING Phase 1

Adjuvant Concurrent Immunotherapy and Radiotherapy for the Treatment of Bladder Cancer

NCT06586255

RECRUITING

Healthy Volunteers Study

NCT06962059

RECRUITING Phase 2

Hypofractionated WPPT With HDR Boost

NCT06591819

RECRUITING NA

BHB & CAR-T for Lymphomas

NCT06610344

RECRUITING

QuantifyHER: Quantitative Immunofluorescence and/or RT-qPCR for Measuring HER2 in HER2-low Metastatic Breast Cancer

NCT06551116

RECRUITING NA

Noncombustible Nicotine Delivery Systems as Potential Harm Reduction Tools for Persistent Cigarette Smokers

NCT06372899

RECRUITING NA

Community Support Program for Lung Cancer Screening Volume II

NCT06628167

RECRUITING Phase 2

Epcoritamab-CAR T Cells for Large B-cell Lymphomas

NCT06458439

RECRUITING NA

Investigation of β-hydroxybutyrate Supplementation as Chemoprevention in Familial Adenomatous Polyposis

NCT06578637

RECRUITING NA

The Role of Flavor in the Substitutability of E-cigarettes for Combustible Cigarettes Among Persistent Smokers

NCT06264154

RECRUITING Phase 1

FAPI-74 PET/CT in Adults With Fibrosis

NCT06413355

RECRUITING NA

Integrating Telehealth to Advance Lung Cancer Screening

NCT06638554

RECRUITING Phase 2

[18F]FES PET/.CT in Uterine Cancer

NCT05916196

RECRUITING NA

Self-Management for Head and Neck Lymphedema and Fibrosis [PROMISE Trial]

NCT06125743

RECRUITING NA

Assessment of a Radiomics-based Computer-Aided Diagnosis Tool for Pulmonary nodulES

NCT05968898

RECRUITING

Prostate Tissue BioBank

NCT06659614

RECRUITING Phase 2

PROton Therapy for Post Surgical Treatment of GYNecologic Cancer

NCT05758688

RECRUITING

Assessment of Geriatric Evaluations Impact on New AML Guidance

NCT05909501

RECRUITING Early Phase 1

FES BPET-DBT in Newly Diagnosed Breast Cancer

NCT05659797

RECRUITING NA

Strategies to Close the Gap From Cervical Cancer Diagnosis to Treatment in Botswana

NCT05952141

RECRUITING Phase 1

Tocilizumab and Atezolizumab in Adults With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Refractory to 1st Line Immune Checkpoint Inhibitor-Based Therapy

NCT04691817

RECRUITING Phase 2

Limited-duration Teclistamab

NCT05932680

RECRUITING

QOL and Sarcopenia in Patients With Ascites

NCT05726747

RECRUITING Phase 2

ChatBot and Activity Monitoring in Patients Undergoing Chemoradiotherapy

NCT05318027

RECRUITING Early Phase 1

Neoadjuvant Pembrolizumab and Lenvatinib for Renal Cell Carcinoma

NCT05733715

RECRUITING

FTT PET/CT in Metastatic Prostate Cancer

NCT05242744

RECRUITING

Collection of Circulating Biomarkers in Pancreatic Cancer

NCT05743049

RECRUITING NA

Improve Outcomes for Older Allogeneic Transplant Recipients

NCT05612789

RECRUITING Phase 2

Neoadjuvant PD-1 Blockade in Resectable Merkel Cell Carcinoma

NCT05496036

RECRUITING NA

WBSI Guided Personalized Delivery of TTFields

NCT05086497

RECRUITING Phase 1

Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM)

NCT03760575

RECRUITING

Role of the Immune Environment in Response to Therapy in Breast Cancer

NCT05396612

RECRUITING NA

eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Cancer

NCT05427240

RECRUITING Phase 1

SBRT With Atezo/Bev for HCC

NCT05488522

RECRUITING NA

Comparing Two Ways to Manage Head and Neck Lymphedema

NCT05182229

RECRUITING Phase 2

CAR-T Followed by Bispecific Antibodies

NCT04889716

RECRUITING Phase 2

ABemacicliB or Abemaciclib and HydroxYchloroquine to Target Minimal Residual Disease in Breast Cancer

NCT04523857

RECRUITING Phase 2

CapTemY90 for Grade 2/3 NET Liver Metastases

NCT04339036

RECRUITING Phase 2

Avelumab or Hydroxychloroquine with or Without Palbociclib to Eliminate Dormant Breast Cancer

NCT04841148

RECRUITING

CTNNA1 Familial Expansion Study

NCT05126290

RECRUITING NA

Physiologic MR Imaging of Salivary Gland Tumors

NCT04452162

RECRUITING Phase 2

Carboplatin, Taxane And Ramucirumab for Patients With NSCLC After Pemetrexed or Pembrolizumab Maintenance

NCT04332367

RECRUITING

Autoimmunity After Checkpoint Blockade

NCT04119713

RECRUITING

Li-Fraumeni Syndrome/TP53 Biobank

NCT04367246

RECRUITING Phase 1

[18F] F-GLN by PET/CT in Breast Cancer

NCT03863457

RECRUITING Phase 1

Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer

NCT03546829

RECRUITING Phase 2

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

NCT03646617

RECRUITING

Frailty Phenotype Assessments to Optimize Treatment Strategies for Older Patients With Hematologic Malignancies

NCT03680677

RECRUITING NA

PENN-Surveillance Markers of Utility for Recurrence After (Neo)Adjuvant Therapy for Breast Cancer

NCT02732171

RECRUITING Phase 1

Phase I Pilot Study of Biodistribution, Metabolism and Excretion of Novel Radiotracer [18F]Fluorthanatrace (FTT) by PET/CT

NCT02637934

RECRUITING

Preliminary Evaluation of Screening for Pancreatic Cancer in Patients With Inherited Genetic Risk

NCT02478892

RECRUITING NA

Ovarian Tissue Transplantation

NCT01870752

RECRUITING

Protocol for Facilitating the Acquisition of Research Bone Marrow and Blood Samples

NCT01985919

RECRUITING

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

NCT02346435

RECRUITING

The Radiation Oncology Registry and Biosample Repository

NCT01577251

ACTIVE NOT RECRUITING NA

Increasing Screening for Cancer Using EHR-Nudges Replication

NCT06995703

ACTIVE NOT RECRUITING

Polygenic Risk Scores and Multi-cancer Early Detection for Ovarian Cancer

NCT06436248

ACTIVE NOT RECRUITING NA

Early Point-of-Service Social and Behavioral Determinants of Health (SBDOH) Screening and Enhanced Navigation on Care Delivery for Patients With Breast Cancer

NCT06019988

ACTIVE NOT RECRUITING NA

Lipiodol Deposition Using Endhole vs. Pressure-Modulated Delivery

NCT06204159

ACTIVE NOT RECRUITING NA

Nudge to Gynecologic Oncology

NCT06451263

ACTIVE NOT RECRUITING NA

Project Looking-Glass Evaluation

NCT06056063

ACTIVE NOT RECRUITING NA

Increasing Adherence to Lung Cancer Screening

NCT05832008

ACTIVE NOT RECRUITING NA

Behavioral Economic Approaches for Population-Based Colorectal Cancer Screening

NCT05693649

ACTIVE NOT RECRUITING NA

The Association Between CBT-I Dose, Sleep Duration, and Fatigue in Breast Cancer Patients

NCT05226078

ACTIVE NOT RECRUITING Phase 2

Shortened Course Adjuvant Radiotherapy Following TORS

NCT05714657

ACTIVE NOT RECRUITING

Vaccine Responses in Cancer

NCT06605625

ACTIVE NOT RECRUITING NA

Understanding Quality of Life Among Patients With Cancer Receiving Palliative Care

NCT05331625

ACTIVE NOT RECRUITING Phase 2

RADVAX™ for Relapsed/Refractory Non-Hodgkin Lymphoma: A Phase II Trial of Pembrolizumab + Low Dose Radiotherapy

NCT04827862

ACTIVE NOT RECRUITING NA

Preliminary Investigation of β-hydroxybutyrate Supplementation in Colorectal Cancer Prevention

NCT05338307

ACTIVE NOT RECRUITING Phase 2

XmAb20717 in Advanced Biliary Tract Cancers

NCT05297903

ACTIVE NOT RECRUITING

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Prostate Cancer

NCT05096338

ACTIVE NOT RECRUITING

Mechanisms, Predictors, and Social Determinants of Cardiotoxicity in Breast Cancer

NCT05078190

ACTIVE NOT RECRUITING

Abbreviate or FAST Breast MRI for Supplemental Breast Cancer Screening for Black Women at Average Risk and Dense Breasts

NCT04854304

ACTIVE NOT RECRUITING NA

Telehealth Weight Loss Program for Breast Cancer Survivors

NCT04855552

ACTIVE NOT RECRUITING NA

Effectiveness of MyCancerGene to Optimize Genetic Testing Outcomes

NCT04774445

ACTIVE NOT RECRUITING Phase 1

INO 5401 Vaccination in BRCA1/2 Mutation Carriers

NCT04367675

ACTIVE NOT RECRUITING NA

Implementation Strategies for Monitoring Adherence in Real Time

NCT04347161

ACTIVE NOT RECRUITING Phase 1

BreastVAX: Radiation Boost to Enhance Immune Checkpoint Blockade Therapy

NCT04454528

ACTIVE NOT RECRUITING

Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy

NCT04305613

ACTIVE NOT RECRUITING Phase 2

Adjuvant Treatment Determined By Pathological Response To Neoadjvuant Nivolumab

NCT04013854

ACTIVE NOT RECRUITING Phase 2

Niraparib/TTFields in GBM

NCT04221503

ACTIVE NOT RECRUITING

BRCA1/2 Flu Vaccine

NCT04499534

ACTIVE NOT RECRUITING NA

Ostomy Rural Telehealth Training Cancer Survivors

NCT03913715

ACTIVE NOT RECRUITING Phase 2

Neoadjuvant PD-1 Blockade in Patients with Stage IIB/C Melanoma

NCT03757689

ACTIVE NOT RECRUITING NA

TORS De-Intensification Protocol Version 2.0: Dose and Volume Reduction in the Neck

NCT03729518

ACTIVE NOT RECRUITING NA

Personalized Radiation Therapy for GBM

NCT03477513

Phase Distribution

PhaseTrial count
Phase 1 93
Phase 2 79
Phase 3 1

What the Pipeline for Abramson Cancer Center at Penn Medicine Shows

According to the ClinicalTrials.gov registry, Abramson Cancer Center at Penn Medicine is linked to 332 US clinical trials across every stage of research activity. Of those, 236 studies are currently recruiting — about 71% of the sponsor's indexed portfolio — and 52 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Abramson Cancer Center at Penn Medicine reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 172 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Abramson Cancer Center at Penn Medicine is Breast Cancer with 20 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial