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2026 data Public-data reference. official source

Normal Physiology

Open-data reference.

26 US clinical trials · 20 currently recruiting

Active & Recent Trials

RECRUITING 10,200 participants

Perception, Sensation, Cognition and Action in Humans

National Eye Institute (NEI)

NCT03407066

RECRUITING 10,000 participants

Clinical and Scientific Assessment of Pain and Painful Disorders

National Center for Complementary and Integrative Health (NCCIH)

NCT02707029

RECRUITING 2,378 participants

Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

National Institute of Neurological Disorders and Stroke (NINDS)

NCT02629107

RECRUITING 2,000 participants

A Natural History Study of Metabolic Sizing in Health and Disease

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT05398783

RECRUITING 2,000 participants

NIEHS Repository of Stored Biological Samples for Future Use

National Institute of Environmental Health Sciences (NIEHS)

NCT05666739

RECRUITING 1,000 participants

Development of 3T Magnetic Resonance Research Methods for NIA Studies

National Institute on Aging (NIA)

NCT01324206

RECRUITING NA 700 participants

Sociocultural & Biobehavioral Influences on Pain Expression and Assessment

National Center for Complementary and Integrative Health (NCCIH)

NCT03258580

RECRUITING NA 620 participants

Defining Neurobiological Links Between Substance Use and Mental Illness

National Institute on Drug Abuse (NIDA)

NCT05538910

RECRUITING Early Phase 1 600 participants

Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making

National Institute on Drug Abuse (NIDA)

NCT06561828

RECRUITING 550 participants

Development and Validation of Learning and Decision-Making Tasks

National Institute on Drug Abuse (NIDA)

NCT05707806

RECRUITING NA 500 participants

Neural and Psychological Mechanisms of Pain Perception

National Center for Complementary and Integrative Health (NCCIH)

NCT02446262

RECRUITING NA 200 participants

MRS Measurement of Glutamate and GABA Metabolism in Brain

National Institute of Mental Health (NIMH)

NCT00109174

RECRUITING 200 participants

Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects

National Institute of Neurological Disorders and Stroke (NINDS)

NCT05604534

RECRUITING NA 192 participants

Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT02535702

RECRUITING 150 participants

Investigating the Impact of Obesity on Pubertal Development in Girls

National Institute of Environmental Health Sciences (NIEHS)

NCT02583646

RECRUITING 150 participants

Investigational Use of Neuromuscular Ultrasound

National Institute of Neurological Disorders and Stroke (NINDS)

NCT05237973

RECRUITING NA 120 participants

The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT05545306

RECRUITING 114 participants

Influence of Brain Oscillation-Dependent TMS on Motor Function

National Institute of Neurological Disorders and Stroke (NINDS)

NCT03288220

RECRUITING NA 75 participants

Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array

National Institute of Mental Health (NIMH)

NCT04950309

RECRUITING NA 48 participants

Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms

Massachusetts General Hospital

NCT05829044

COMPLETED 359 participants

Volunteer Screening for Vaccine and Antivirals Clinical Trials

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01593709

COMPLETED NA 43 participants

Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory

National Institute of Neurological Disorders and Stroke (NINDS)

NCT04694131

COMPLETED 40 participants

Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex

National Institute of Neurological Disorders and Stroke (NINDS)

NCT04431011

COMPLETED NA 39 participants

Study of Volition: Behavioral Analysis and Clinical Neurophysiological Analysis

National Institute of Neurological Disorders and Stroke (NINDS)

NCT04344470

COMPLETED Phase 1 25 participants

Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRI

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NCT03326245

COMPLETED 10 participants

Studying Cell Immune Responses to a Live Flu Vaccine in Healthy Adults

National Institute of Allergy and Infectious Diseases (NIAID)

NCT01730144

Reading the Normal Physiology Trial Landscape

ClinicalTrials.gov lists 26 US studies indexed under Normal Physiology, and 20 of those are currently open to recruitment — roughly 77% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Normal Physiology shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Normal Physiology is led by National Institute of Neurological Disorders and Stroke (NINDS) with 7 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Normal Physiology?

PlainTrial tracks 26 US clinical trials for Normal Physiology, of which 20 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Normal Physiology?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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