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NCT05545306 · ClinicalTrials.gov registry record · NA
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
A NA study of Obesity and Healthy Volunteers, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT05545306 is a NA study of Obesity and Healthy Volunteers that is actively recruiting participants, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 120 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state.
The verdict
NCT05545306, a NA study of Obesity and Healthy Volunteers, is actively recruiting participants, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Diet-induced thermogenesis (DIT) is the amount of energy one s body uses to eat food, absorb the nutrients from the food, and process those nutrients. Researchers would like to understand more about how changing the balances of protein, fat, carbohydrates, and total calories in the diet can affect DIT. Objective: To learn how different diets can change a person s DIT. Eligibility: Healthy people aged 18 to 60 years who have not intentionally lost weight in the past 6 months. Design: Participants will stay in a clinic for about 35 days. They will eat only the food provided. They will receive 8 different diets during the study, including 7 test diets. Participants will undergo multiple tests. They will be screened with blood and urine tests and a test of their heart function. During the first few days: Their waist, thigh, and neck circumference will be measured. They will have a DXA scan: They will lie on a padded table for about 20 minutes while an instrument measures the amount of fat in their body. They will be tested for diabetes. They will answer questionnaires about topics including eating behavior, hunger, and stress. Throughout the study: Their weight will be measured daily. Blood tests will be repeated. They will stay in a metabolic chamber a total of 9 times. They will remain in a closed room for 24 hours while researchers monitor the room temperature and levels of oxygen and carbon dioxide. Participants will collect all their urine for each 24-hour period. ...
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT +200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat
- DIETARY_SUPPLEMENT fasting
- DIETARY_SUPPLEMENT -50% of energy balance requirements. 50% of calories from carbohydrates, 20% from protein, and 30% from fat
- DIETARY_SUPPLEMENT +150% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat
- DIETARY_SUPPLEMENT +200% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein
Study Locations (1)
Arizona
- NIDDK, Phoenix - Phoenix
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2023-06-06 |
| Est. Completion | 2027-02-02 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05545306
The ClinicalTrials.gov registry entry for NCT05545306 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 120 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (85% lower). The listed sponsor is National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Obesity appearing as the primary indexed condition, and to 5 interventions - of which +200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat is the first listed.
NCT05545306 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.
Frequently Asked Questions
What is clinical trial NCT05545306 about?
NCT05545306 is a clinical study titled "The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure". Background: Diet-induced thermogenesis (DIT) is the amount of energy one s body uses to eat food, absorb the nutrients from the food, and process those nutrients. Researchers would like to understand more about how changing the balances of protein, fat, carbohydrates, and total calories in the diet...
What is the current status of trial NCT05545306?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2023-06-06. Estimated completion is 2027-02-02.
What conditions does trial NCT05545306 study?
This clinical trial studies the following conditions: Obesity, Healthy Volunteers, Normal Physiology.
What interventions are being tested in trial NCT05545306?
The interventions under investigation include: +200% of dietary requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat (DIETARY_SUPPLEMENT), fasting (DIETARY_SUPPLEMENT), -50% of energy balance requirements. 50% of calories from carbohydrates, 20% from protein, and 30% from fat (DIETARY_SUPPLEMENT), +150% of energy balance requirements, 50% of calories from carbohydrates, 20% from protein, and 30% from fat (DIETARY_SUPPLEMENT), +200% of dietary requirements, 51% of the calories from carbohydrates, 46%, from fat and 3% from protein (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT05545306?
This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05545306 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Related
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