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NCT05829044 · ClinicalTrials.gov registry record · NA
Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms
A NA study of Normal Physiology, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT05829044: Recruiting NA study of Normal Physiology, sponsored by Massachusetts General Hospital.
NCT05829044 is a NA study of Normal Physiology that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 48 participants, below the 1,291-participant average among 25 other Normal Physiology trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05829044, a NA study of Normal Physiology, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn how the pupil responds to different light stimuli and how that relates to sleep and daily rhythms in healthy people of different ages. The main questions it aims to answer are: * Does the eye's pupil response to light stimuli differ by the sex and age of the participant? * Is the eye's pupil response to light stimuli related to each participant's sleep timing, their body clock timing, and their hormone responses to light. Participants will have a special eye exam and complete questionnaires before starting the study to see if they can participate. If they can participate, they will wear a special watch that monitors their activity and light levels for one week. Then they will live in a research room at the Mass General Hospital for 3 days/2 nights during which we will test their pupil response to light, their body clock timing, and their hormone responses to light.
Primary Outcome
Pupil size as measured by pupillometry
Conditions Studied
Interventions
- DEVICE Pupillometry
- DEVICE Light box exposure
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2023-12-01 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
What NCT05829044 shows while recruiting
NCT05829044 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 1,291-participant average among 25 other Normal Physiology trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Normal Physiology appearing as the primary indexed condition, and to 2 interventions - of which Pupillometry is the first listed.
NCT05829044 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT05829044 about?
NCT05829044 is a clinical study titled "Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms". The goal of this clinical trial is to learn how the pupil responds to different light stimuli and how that relates to sleep and daily rhythms in healthy people of different ages. The main questions it aims to answer are: * Does the eye's pupil response to light stimuli differ by the sex and age of...
What is the current status of trial NCT05829044?
This trial is currently recruiting. It is a NA study. The enrollment target is 48 participants. The study started on 2023-12-01. Estimated completion is 2026-06-30.
What conditions does trial NCT05829044 study?
This clinical trial studies the following conditions: Normal Physiology.
What interventions are being tested in trial NCT05829044?
The interventions under investigation include: Pupillometry (DEVICE), Light box exposure (DEVICE).
Who is sponsoring clinical trial NCT05829044?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05829044 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Normal Physiology
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05829044's enrollment target sits among peer trials
48 21st of 25 higher than 5 of 25 other Normal Physiology trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Normal Physiology trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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