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2026 data Public-data reference. official source

Autoimmune Diseases

Open-data reference.

26 US clinical trials · 14 currently recruiting

Active & Recent Trials

RECRUITING 10,000 participants

Collection and Distribution of Biospecimens for Novel Research Uses

iSpecimen

NCT03848962

RECRUITING Phase 1 5,000 participants

Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions

Thomas Advanced Medical

NCT04684602

RECRUITING 2,500 participants

IMPACT - AndHealth Autoimmune Research Registry

AndHealth

NCT05883371

RECRUITING NA 1,170 participants

Testimonials and Navigation in Rheumatology

University of Alabama at Birmingham

NCT06469788

RECRUITING 1,000 participants

Maternal Autoimmune Disease Research Alliance (MADRA) Registry

Duke University

NCT03276923

RECRUITING 800 participants

Biologics And Clinical Immunology Cohort at Sinai

Icahn School of Medicine at Mount Sinai

NCT04784364

RECRUITING 500 participants

Rheumatology Diet Study

University of Central Florida

NCT06339957

RECRUITING 500 participants

Ovarian Tissue Cryopreservation for Fertility Preservation

University of Pittsburgh

NCT05875155

RECRUITING 300 participants

Deciphering the Genetic Architecture of Autoimmune Diseases

National Human Genome Research Institute (NHGRI)

NCT06948110

RECRUITING 300 participants

A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease

TScan Therapeutics

NCT06587828

RECRUITING Phase 1 30 participants

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

Arcellx

NCT06626919

RECRUITING NA 30 participants

VNS Prospective Neuromodulation of Immune and Gastrointestinal Systems

University of Louisville

NCT03953768

RECRUITING Phase 4 20 participants

Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease

Toyos Clinic

NCT06964269

RECRUITING 16 participants

X-linked Moesin Associated Immunodeficiency

Institut National de la Santé Et de la Recherche Médicale, France

NCT06278337

ACTIVE NOT RECRUITING NA 1,325 participants

A Trial of Academic Detailing to Promote Prescribing of Biosimilars

Brigham and Women's Hospital

NCT07221890

ACTIVE NOT RECRUITING Phase 2 34 participants

Oral Ifetroban to Treat Diffuse Cutaneous Systemic Sclerosis (SSc) or SSc-associated Pulmonary Arterial Hypertension

Cumberland Pharmaceuticals

NCT02682511

ACTIVE NOT RECRUITING 32 participants

Immuno-Oncology Database and Bioregistry

UNC Lineberger Comprehensive Cancer Center

NCT04656873

COMPLETED Phase 3 433 participants

Golimumab in Rheumatoid Arthritis Participants With an Inadequate Response to Etanercept (ENBREL) or Adalimumab (HUMIRA)

Janssen Biotech

NCT01004432

COMPLETED NA 131 participants

Day and Night Closed-loop in Young People With Type 1 Diabetes

Jaeb Center for Health Research

NCT02925299

COMPLETED Phase 1 112 participants

A Study to Investigate the Effects of CBP-307 on the Heart Rate-corrected QT Interval (QTc) in Healthy Subjects

Connect Biopharma Australia Pty

NCT04818229

COMPLETED Phase 3 80 participants

Phase III Study of a Topical Gel Formulation for Treatment and Prevention of Raynaud's Phenomenon

MediQuest Therapeutics

NCT00419419

COMPLETED 60 participants

Study of Silicone-Associated Connective Tissue Diseases

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NCT00001330

COMPLETED 48 participants

Humoral and T-Cell Responses to COVID-19 Vaccination in Multiple Sclerosis Patients Treated With Ocrelizumab Treated With Ocrelizumab or Natalizumab

Dragonfly Research

NCT04837651

COMPLETED NA 30 participants

Photo-Protection Trial (NB-UVB vs. Placebo) in High-risk Hospitalized COVID-19 Patients

Cytokind

NCT04818970

COMPLETED Phase 3 10 participants

Treatment of Childhood Onset Psychiatric Disorders With Intravenous Immunoglobulin (IVIg)

National Institute of Mental Health (NIMH)

NCT00001768

COMPLETED Phase 1 1 participants

Use of Cross-linked Donor Corneas as Carriers for the Boston Keratoprosthesis

Joseph B. Ciolino, MD

NCT01582880

Phase Distribution

PhaseTrial count
Early Phase 1 4
Phase 2 1
Phase 3 3
Phase 4 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Autoimmune Diseases Trial Landscape

ClinicalTrials.gov lists 26 US studies indexed under Autoimmune Diseases, and 14 of those are currently open to recruitment — roughly 54% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Autoimmune Diseases shows 4 late-stage studies (Phase 3 and Phase 4 combined) alongside 5 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Autoimmune Diseases is led by Dragonfly Research with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 26 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Autoimmune Diseases?

PlainTrial tracks 26 US clinical trials for Autoimmune Diseases, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Autoimmune Diseases?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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