Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT02535702 · ClinicalTrials.gov registry record · NA
Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction
A NA study of Normal Physiology, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- Recruiting
- Registry status
- NA
- Development phase
- 192
- Enrollment target
- 1
- Study location
NCT02535702: Recruiting NA study of Normal Physiology, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
NCT02535702 is a NA study of Normal Physiology that is actively recruiting participants, run by National Institute on Alcohol Abuse and Alcoholism (NIAAA). The registered enrollment target is 192 participants, below the 1,285-participant average among 25 other Normal Physiology trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02535702, a NA study of Normal Physiology, is actively recruiting participants, sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- RECRUITING
- Registry status
- NA
- Development phase
- 192 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Abusing alcohol, drugs, and other substances can cause serious health problems. These substances also can affect brain function. Researchers want to learn more about brain function by using magnetic resonance imaging (MRI). This uses a magnetic field and radio waves to take pictures of the brain. Objective: To develop new ways to use MRI to study the brain. Eligibility: Healthy people 18 years of age or older. Design: Participants will be screened with a medical history, physical exam, and blood and urine tests. They will answer questions about their drug use and psychiatric history. They will be asked about family history of alcoholism or drug abuse. Participants will answer questions to see if they can participate in MRI. Participants will have MRI scans. The scanner is a metal cylinder in a strong magnetic field. Participants will lie on a table that slides in and out of the cylinder. A device called a coil may be placed over the head. Each sub-study will include up to 3 different MRI visits. Participants can be in multiple sub-studies. But they can have only 1 MRI per week and 20 per year. During MRI visits, participants may have urine collected. They may get another MRI questionnaire. Participants may have a clinical MRI brain scan. This may show physical problems in the brain. During some scans, participants may perform simple movement, memory, and thinking tasks. Participants may be connected to a machine to monitor brain activity during the scan. Small metal electrodes will be placed on the scalp. A gel will be placed in the space between the electrodes and the scalp. ...
Primary Outcome
MRI: we will analyze measures such as the amplitude and the reliability of the test-retest measures of fMRI signals; functional connectivity metrics; tractography between seed and target regions of interest (diffusion tensor imaging, DTI); morphometry of brain regions (using automatic segmentation and voxel-brain morphometry, VBM); and brain metabolite levels in regions of interest (using MR spectroscopy, MRS).
Conditions Studied
Interventions
- OTHER In vivo MRS
- OTHER fMRI
- OTHER EEG/EOG
- OTHER Stimulation tasks
- OTHER NSPRD
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 192 participants |
| Start Date | 2016-06-28 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT02535702 shows while recruiting
NCT02535702 is an interventional study that assigns participants to a tested intervention. The registered 192 participants enrollment target is mid-sized for trials with a published cap, below the 1,285-participant average among 25 other Normal Physiology trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Normal Physiology appearing as the primary indexed condition, and to 5 interventions - of which In vivo MRS is the first listed.
NCT02535702 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT02535702 about?
NCT02535702 is a clinical study titled "Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction". Background: Abusing alcohol, drugs, and other substances can cause serious health problems. These substances also can affect brain function. Researchers want to learn more about brain function by using magnetic resonance imaging (MRI). This uses a magnetic field and radio waves to take pictures of ...
What is the current status of trial NCT02535702?
This trial is currently recruiting. It is a NA study. The enrollment target is 192 participants. The study started on 2016-06-28. Estimated completion is 2026-12-31.
What conditions does trial NCT02535702 study?
This clinical trial studies the following conditions: Normal Physiology.
What interventions are being tested in trial NCT02535702?
The interventions under investigation include: In vivo MRS (OTHER), fMRI (OTHER), EEG/EOG (OTHER), Stimulation tasks (OTHER), NSPRD (OTHER).
Who is sponsoring clinical trial NCT02535702?
This trial is sponsored by National Institute on Alcohol Abuse and Alcoholism (NIAAA), which has 93 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02535702 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Normal Physiology
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02535702's enrollment target sits among peer trials
192 15th of 25 higher than 11 of 25 other Normal Physiology trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Normal Physiology trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Sociocultural & Biobehavioral Influences on Pain Expression and Assessment
RECRUITING · NA
-
Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
RECRUITING · NA
-
Defining Neurobiological Links Between Substance Use and Mental Illness
RECRUITING · NA
-
MRS Measurement of Glutamate and GABA Metabolism in Brain
RECRUITING · NA
-
Impact of Sex and Age on Non-visual Light Input That Affects Sleep and Circadian Rhythms
RECRUITING · NA
-
The Effects of Increasing Caloric Intake on Diet-Induced Thermogenesis and 24h Energy Expenditure
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01492972 · 192 participants · Phase 3
Hypo-fractionated Radiation Therapy With or Without Androgen Suppression for Intermediate Risk Prostate Cancer
- NCT01973881 · 192 participants
Quantitative MRI for Myelofibrosis
- NCT03622359 · 192 participants · NA
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
- NCT05079399 · 192 participants
Biomarker of Diabetic Retinopathy
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI