National Institute of Neurological Disorders and Stroke (NINDS)
National Institute of Neurological Disorders and Stroke (NINDS) sponsors 567 registered US clinical trials on ClinicalTrials.gov, 48 of them currently recruiting, and 467 completed. 16 of these trials are in Phase 3-4 (later-stage) and 158 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 23 trials.
Trial Pipeline
567 total, page 1 of 12
Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma
NCT07416188
Intravenous Brincidofovir as an Antiviral for Treatment of Progressive Multifocal Leukoencephalopathy: A Pilot Study
NCT07511049
Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke
NCT06615973
Distinguishing Tics and Functional Tics Using Clinical Neurophysiological Techniques
NCT07137442
Predicting Future Errors During Skill Performance
NCT06707207
DDAVP for Pituitary Adenoma
NCT04569591
A Prospective Natural History and Outcome Measure Validation Study of Congenital Myasthenic Syndromes
NCT06630650
Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort
NCT06472622
Cross-Sectional Evaluation of Persistence of SARS-CoV-2 Remnants After Recovery From Acute Infection
NCT06577467
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
NCT02531880
Data Collection of Standard Care of Patients in the EMG Section
NCT05041387
Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology
NCT06203626
Central Nervous System Uptake of Anti-CD8+ T Cell Minibodies in Multiple Sclerosis and Progressive Multifocal Leukoencephalopathy
NCT05849467
NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)
NCT05375812
Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects
NCT05604534
Natural History Protocol for Movement Disorders
NCT05413291
Investigational Use of Neuromuscular Ultrasound
NCT05237973
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health
NCT04573062
Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)
NCT04944940
Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis
NCT04799288
The Beneficial Effects of Naps on Motor Learning
NCT04312126
Clinical Manifestations and Biomarkers in Amyotrophic Lateral Sclerosis Type 4 and Other Inherited Neurological Disorders of RNA Processing
NCT04394871
Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
NCT03678389
Influence of Brain Oscillation-Dependent TMS on Motor Function
NCT03288220
Investigating Epilepsy: Screening and Evaluation
NCT03478852
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
NCT03225144
Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques
NCT02784210
Pathological Basis of MRI Signal Changes in Multiple Sclerosis
NCT02659956
Tumor Related Epilepsy
NCT02639325
Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli
NCT02629107
Inflammatory and Infectious Diseases of the Nervous System
NCT02435810
Deep Brain Stimulation Therapy in Movement Disorders
NCT02119611
Noninvasive Pre-surgical Evaluation of Patients With Focal Epilepsy and Establishment of a Normative Imaging Database
NCT02107989
Thinking and Memory Problems in People With HIV
NCT01875588
Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers
NCT01900132
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
NCT01730131
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
NCT01568658
Deep Brain Stimulation Surgery for Movement Disorders
NCT01581580
Surgery as a Treatment for Medically Intractable Epilepsy
NCT01273129
Natural History Study of Patients With Neurofibromatosis Type 2
NCT00598351
Evaluation and Treatment of Neurosurgical Disorders
NCT00060541
Phenotype/Genotype Correlations in Movement Disorders
NCT00018889
Natural History of Stroke: Cause and Development
NCT00009243
Study of New Magnetic Resonance Imaging Methods of the Brain
NCT00004577
Study of Inherited Neurological Disorders
NCT00004568
Evaluation of Patients With HAM/TSP
NCT00001778
Magnetic Resonance Imaging (MRI) to Evaluate Activity of Multiple Sclerosis (MS)
NCT00001248
Botulinum Toxin for the Treatment of Involuntary Movement Disorders
NCT00001208
Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)
NCT07204977
Non-invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
NCT05155059
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 80 |
| Phase 2 | 78 |
| Phase 3 | 11 |
| Phase 4 | 5 |
Therapeutic Areas
What the Pipeline for National Institute of Neurological Disorders and Stroke (NINDS) Shows
According to the ClinicalTrials.gov registry, National Institute of Neurological Disorders and Stroke (NINDS) is linked to 567 US clinical trials across every stage of research activity. Of those, 48 studies are currently recruiting, about 8% of the sponsor's indexed portfolio, and 467 are already marked complete, representing roughly 82% of the total.
The phase mix for National Institute of Neurological Disorders and Stroke (NINDS) reports 16 late-stage studies (Phase 3 and Phase 4 combined) and 158 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Neurological Disorders and Stroke (NINDS) is Healthy with 23 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.