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NCT05707806 · ClinicalTrials.gov registry record
Development and Validation of Learning and Decision-Making Tasks
A clinical trial of Normal Physiology, sponsored by National Institute on Drug Abuse (NIDA).
- Recruiting
- Registry status
- 550
- Enrollment target
- 1
- Study location
NCT05707806: Recruiting study of Normal Physiology, sponsored by National Institute on Drug Abuse (NIDA).
NCT05707806 is a study of Normal Physiology that is actively recruiting participants, run by National Institute on Drug Abuse (NIDA). The registered enrollment target is 550 participants, below the 1,271-participant average among 25 other Normal Physiology trials with a reported enrollment target (57% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05707806, a study of Normal Physiology, is actively recruiting participants, sponsored by National Institute on Drug Abuse (NIDA).
- RECRUITING
- Registry status
- 550 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Substance use disorders (SUD) can be considered disorders in the way people process incentives, learn, and make decisions. To understand why some people develop SUD, researchers need to develop reliable tests that show how people think and learn. This natural history study seeks to develop a set of tasks that could then be used to test how people learn and make decisions. Objective: To develop and validate behavioral tasks that could be used in future studies. Eligibility: Healthy people aged 18-45 years from the Baltimore area. They must also be enrolled in the NIDA screening protocol. Design: Participants will perform different tasks. Most tasks require 1-4 study visits; some may require up to 12. Visits are 1-14 days apart. All visits will last about 1-7 hours. Participants will perform tasks on a computer. As they work they may be given different stimuli: Smells. Participants will sniff odors through a plastic tube or mask on their nose. Flavors. Participants will wear a mouthpiece and small amounts of different flavored liquids will be placed in their mouth. Pictures. Participants will look at different images. Sounds. Participants will wear headphones and various sounds will be played for them. Food. Participants may be asked to eat a meal before, during, or after a task. The researchers will provide the meal. During each task, participants will wear sensors to monitor their heart rate, blood pressure, breathing, and other physical changes in their bodies. Some participants will have a functional magnetic resonance imaging (fMRI) scan. They will lie on a table that slides into a cylinder. They will perform tasks on a computer screen during the fMRI.
Primary Outcome
to determine if the developed tasks reliably and appropriately measure specific cognitive functions, and if they yield measurable and interpretable fMRI results in the associated brain systems.
Conditions Studied
Interventions
- DEVICE MRI
Study Locations (1)
Maryland
- National Institute on Drug Abuse - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 550 participants |
| Start Date | 2023-03-29 |
| Est. Completion | 2032-12-31 |
What NCT05707806 shows while recruiting
NCT05707806 is an observational study that tracks outcomes without assigning an intervention. The registered 550 participants enrollment target is mid-sized for trials with a published cap, below the 1,271-participant average among 25 other Normal Physiology trials with a reported enrollment target (57% lower).
The record links to 1 condition, with Normal Physiology appearing as the primary indexed condition, and to 1 intervention - of which MRI is the first listed.
NCT05707806 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05707806 about?
NCT05707806 is a clinical study titled "Development and Validation of Learning and Decision-Making Tasks". Background: Substance use disorders (SUD) can be considered disorders in the way people process incentives, learn, and make decisions. To understand why some people develop SUD, researchers need to develop reliable tests that show how people think and learn. This natural history study seeks to deve...
What is the current status of trial NCT05707806?
This trial is currently recruiting. The enrollment target is 550 participants. The study started on 2023-03-29. Estimated completion is 2032-12-31.
What conditions does trial NCT05707806 study?
This clinical trial studies the following conditions: Normal Physiology.
What interventions are being tested in trial NCT05707806?
The interventions under investigation include: MRI (DEVICE).
Who is sponsoring clinical trial NCT05707806?
This trial is sponsored by National Institute on Drug Abuse (NIDA), which has 335 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05707806 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05707806's enrollment target sits among peer trials
550 10th of 25 higher than 16 of 25 other Normal Physiology trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Normal Physiology trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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