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NCT04431011 · ClinicalTrials.gov registry record
Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex
A clinical trial of Normal Physiology, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 40
- Enrollment target
- 1
- Study location
NCT04431011: Completed study of Normal Physiology, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT04431011 is a study of Normal Physiology that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 40 participants, below the 1,291-participant average among 25 other Normal Physiology trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04431011, a study of Normal Physiology, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: Training in a new motor skill often involves periods of active practice and periods of rest. During early motor skill learning, improvements in performance usually happen during the short rest periods between practice sessions. Researchers want to use improved imaging techniques to study the contributions of specific parts of the brain to how people learn and retain movement skills. Objective: To learn the part played by different layers in the brain in retaining a newly learned movement skill. Eligibility: Healthy, right-handed, English-speaking people age 18-50. Design: Participants will be screened with: * Medical and neurological history * Medicine review * Physical exam * Neurological exam. Participants may have 2 magnetic resonance imaging (MRI) scans of the brain. During the MRI, they will lie in the scanner. The scanner makes noise. They will get earplugs. Participants will have behavior testing. A specific order of keys will be displayed on a computer screen. Participants will practice typing the keys with their left hand 36 times (in 10-second blocks). They will repeat this test with a random order of keys. Participants will see single numbers displayed one after the other on the computer screen. They will make single tap responses using the finger that corresponds with the number on the screen. Participants will have up to 4 study sessions. Each session will take about 5 hours.
Primary Outcome
To address this question, we will measure neural activations across cortical laminae in M1 while participants consolidate a newly acquired motor skill.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-04-21 |
| Est. Completion | 2024-12-09 |
What the finished NCT04431011 record still lists
NCT04431011 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,291-participant average among 25 other Normal Physiology trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Normal Physiology appearing as the primary indexed condition, and to 0 interventions.
NCT04431011 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04431011 about?
NCT04431011 is a clinical study titled "Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex". Background: Training in a new motor skill often involves periods of active practice and periods of rest. During early motor skill learning, improvements in performance usually happen during the short rest periods between practice sessions. Researchers want to use improved imaging techniques to stud...
What is the current status of trial NCT04431011?
This trial is currently completed. The enrollment target is 40 participants. The study started on 2021-04-21. Estimated completion is 2024-12-09.
What conditions does trial NCT04431011 study?
This clinical trial studies the following conditions: Normal Physiology.
Who is sponsoring clinical trial NCT04431011?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04431011 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT04431011's enrollment target sits among peer trials
40 23rd of 25 higher than 3 of 25 other Normal Physiology trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Normal Physiology trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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