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NCT04344470 · ClinicalTrials.gov registry record · NA
Study of Volition: Behavioral Analysis and Clinical Neurophysiological Analysis
A NA study of Normal Physiology, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- NA
- Development phase
- 39
- Enrollment target
- 1
- Study location
NCT04344470: Completed NA study of Normal Physiology, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT04344470 is a NA study of Normal Physiology that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 39 participants, below the 1,291-participant average among 25 other Normal Physiology trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04344470, a NA study of Normal Physiology, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- NA
- Development phase
- 39 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: 'Free will' can be defined as the belief that people have control over their thoughts and movements. The topic of free will is controversial and is still being debated. Science has only partial answers to questions about free will, so researchers want to learn more about it. They want to assess the role of consciousness when intentions are present with behavior. This could help to explain the causal role of consciousness in movement or decisions. Objective: To learn more about free will. Eligibility: Healthy, right-handed adults ages 25-45 Design: Participants will be screened with medical history, physical exam, and neurological exam. Participants will have 1 study visit. It will last up to 4 hours. Participants will sit in a comfortable chair in front of a screen. They will perform some or all of the following tasks. Visual Task. Participants will watch different stimuli on the screen and answer simple questions. Electroencephalography (EEG). An EEG records the electrical activity of the brain ('brain waves'). For the EEG, small electrodes are put on the scalp with an electrode cap. A gel is placed in the space between the electrodes and the scalp. Participants' brain waves will be recorded, including while they decide whether to move their thumb. Choice/Reaction Time Task. Participants will watch different stimuli on the screen and react to them by moving their wrist. During this task, they will wear an EEG cap on their head and electrodes on their arms and wrists. Electromyography. Small electrodes will be attached to participants' skin. Their muscle activity will be recorded while they decide whether to move their wrist and during the movement itself. Transcranial Magnetic Stimulation (TMS): TMS is a non-invasive brain stimulation that uses magnetic field to stimulate nerve cells in your brain. TMS can increase or decrease brain activity in particular area of your brain. TMS operates completely outside of the body and is generally very
Primary Outcome
We will develop a methodological approach to create the best backward masking effect. We will ask the subjects what they saw, to prove the effectiveness of the backward masking.
Conditions Studied
Interventions
- DEVICE EEG
- DEVICE EMG
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 39 participants |
| Start Date | 2020-12-22 |
| Est. Completion | 2024-03-21 |
| Phase | NA |
What the finished NCT04344470 record still lists
NCT04344470 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 1,291-participant average among 25 other Normal Physiology trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Normal Physiology appearing as the primary indexed condition, and to 2 interventions - of which EEG is the first listed.
NCT04344470 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04344470 about?
NCT04344470 is a clinical study titled "Study of Volition: Behavioral Analysis and Clinical Neurophysiological Analysis". Background: 'Free will' can be defined as the belief that people have control over their thoughts and movements. The topic of free will is controversial and is still being debated. Science has only partial answers to questions about free will, so researchers want to learn more about it. They want t...
What is the current status of trial NCT04344470?
This trial is currently completed. It is a NA study. The enrollment target is 39 participants. The study started on 2020-12-22. Estimated completion is 2024-03-21.
What conditions does trial NCT04344470 study?
This clinical trial studies the following conditions: Normal Physiology.
What interventions are being tested in trial NCT04344470?
The interventions under investigation include: EEG (DEVICE), EMG (DEVICE).
Who is sponsoring clinical trial NCT04344470?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04344470 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04344470's enrollment target sits among peer trials
39 24th of 25 higher than 2 of 25 other Normal Physiology trials
participants (enrollment target), bucketed by value
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