National Institute of Environmental Health Sciences (NIEHS)

145 total trials 15 currently recruiting 124 completed

National Institute of Environmental Health Sciences (NIEHS) sponsors 145 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 124 completed. 3 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Asthma, with 8 trials.

Trial Pipeline

145 total, page 1 of 3

RECRUITING Phase 2

FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)

NCT07111065

RECRUITING Phase 2

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

NCT06325696

RECRUITING

NIEHS Repository of Stored Biological Samples for Future Use

NCT05666739

RECRUITING

Observation of Environment and Reproductive-Endocrine Effects

NCT06280807

RECRUITING

Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) Equity

NCT04983251

RECRUITING

Natural History of the Human Biological Response to Environmental Exposure and Injury

NCT04888923

RECRUITING

Reproductive Axis Maturation in the Early Post-Menarchal Years

NCT03986021

RECRUITING

Investigating the Impact of Obesity on Pubertal Development in Girls

NCT02583646

RECRUITING

NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)

NCT02327897

RECRUITING

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

NCT01143480

RECRUITING

Inherited Reproductive Disorders

NCT01500447

RECRUITING

Environmental Risk Factors for the Anti-synthetase Syndrome

NCT01276470

RECRUITING

Personalized Environment and Genes Study

NCT00341237

RECRUITING

Immune Cell Response to Stimuli

NCT00397280

RECRUITING

Adult and Juvenile Myositis

NCT00017914

ACTIVE NOT RECRUITING

Factors Influencing Fertility or Pregnancy Health

NCT04595760

ACTIVE NOT RECRUITING

Gulf Long-Term Follow-Up Study

NCT01287000

NOT YET RECRUITING

A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...

NCT06991751

NOT YET RECRUITING

Stress, Coping, and Sleep Health Study

NCT07566481

NOT YET RECRUITING

A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity

NCT07437976

COMPLETED Phase 2

The Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Clinical Trial

NCT05050916

COMPLETED

Serological Surveillance for COVID-19 in Central North Carolina

NCT04490174

COMPLETED

Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19

NCT04403386

COMPLETED

Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function

NCT02743468

COMPLETED

Study of Exposure to Chemicals in Consumer Products

NCT02471365

COMPLETED

Qualitative Assessment of the Work-Sleep Relationship

NCT03389828

COMPLETED Phase 2

Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis

NCT03267277

COMPLETED NA

CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)

NCT02858336

COMPLETED

Environmental Risk Factors for Myositis in Military Personnel

NCT01734369

COMPLETED

Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity

NCT01780155

COMPLETED

The COX-2 Gene and the Immune System

NCT01678222

COMPLETED

Environmental Polymorphisms Registry Health and Exposures Survey

NCT01688986

COMPLETED Phase 1

Bisphenol A Controlled Exposure Study

NCT01573429

COMPLETED

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

NCT01143519

COMPLETED

Hormonal Regulation of Puberty and Fertility

NCT01511588

COMPLETED

TGF-(Beta) and Susceptibility to RSV

NCT01224691

COMPLETED

Blood Vessel Study

NCT01524549

COMPLETED

Agricultural Health Study Follow-up

NCT01399411

COMPLETED

The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease

NCT01143493

COMPLETED

A Follow-up of the Early Pregnancy Study Cohort.

NCT01132924

COMPLETED

Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing

NCT01087307

COMPLETED Phase 3

Indoor Woodsmoke PM and Asthma

NCT00807183

COMPLETED

Functional Implications of TNF

NCT00729131

COMPLETED

Lung Mucus Hypersecretion and NQO1

NCT00729352

COMPLETED

Biomarker Analysis of Stress

NCT00527384

COMPLETED

PCOS Twin Study - Environmental Factors in the Development of Polycystic Ovary Syndrome, Phase 2

NCT00444288

COMPLETED

Oral Bacteria and Allergic Disease in Children

NCT00438646

COMPLETED

Children With Asthma in New Orleans After Hurricane Katrina

NCT00426634

COMPLETED

The Influence of Breast Cancer Risk and Risk Perception on Lifestyle Behaviors Among Women With a Family History: A Mixed Method Approach

NCT00393406

COMPLETED

Confirmation of Self-Reported Incident ALS Cases in the AARP-Diet and Health (AARP-DH) Cohort

NCT00377351

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Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 5
Phase 3 3

What the Pipeline for National Institute of Environmental Health Sciences (NIEHS) Shows

According to the ClinicalTrials.gov registry, National Institute of Environmental Health Sciences (NIEHS) is linked to 145 US clinical trials across every stage of research activity. Of those, 15 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 124 are already marked complete, representing roughly 86% of the total.

The phase mix for National Institute of Environmental Health Sciences (NIEHS) reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 7 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for National Institute of Environmental Health Sciences (NIEHS) is Asthma with 8 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.