National Institute of Environmental Health Sciences (NIEHS)
National Institute of Environmental Health Sciences (NIEHS) sponsors 145 registered US clinical trials on ClinicalTrials.gov, 15 of them currently recruiting, and 124 completed. 3 of these trials are in Phase 3-4 (later-stage) and 7 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Asthma, with 8 trials.
Trial Pipeline
145 total, page 1 of 3
FAST for DM - Fatty Acid Supplementation Trial (FAST) for Dermatomyositis (DM)
NCT07111065
H01 in Adults With Interstitial Lung Disease (The SOLIS Study)
NCT06325696
NIEHS Repository of Stored Biological Samples for Future Use
NCT05666739
Observation of Environment and Reproductive-Endocrine Effects
NCT06280807
Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) Equity
NCT04983251
Natural History of the Human Biological Response to Environmental Exposure and Injury
NCT04888923
Reproductive Axis Maturation in the Early Post-Menarchal Years
NCT03986021
Investigating the Impact of Obesity on Pubertal Development in Girls
NCT02583646
NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)
NCT02327897
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
NCT01143480
Inherited Reproductive Disorders
NCT01500447
Environmental Risk Factors for the Anti-synthetase Syndrome
NCT01276470
Personalized Environment and Genes Study
NCT00341237
Immune Cell Response to Stimuli
NCT00397280
Adult and Juvenile Myositis
NCT00017914
Factors Influencing Fertility or Pregnancy Health
NCT04595760
Gulf Long-Term Follow-Up Study
NCT01287000
A Natural History of Cardiometabolic Disease Among US Bhutanese: Developing the Cross-Sectional Bhutanese Community of Central Ohio Health Study to Understand Acculturation as Synergizing Socioenvironmental and Biobehavioral Risk Factors Propagating ...
NCT06991751
Stress, Coping, and Sleep Health Study
NCT07566481
A Natural History of Genetic and Environmental Predictors of Pubertal Timing Among Youth With Obesity
NCT07437976
The Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Clinical Trial
NCT05050916
Serological Surveillance for COVID-19 in Central North Carolina
NCT04490174
Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19
NCT04403386
Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function
NCT02743468
Study of Exposure to Chemicals in Consumer Products
NCT02471365
Qualitative Assessment of the Work-Sleep Relationship
NCT03389828
Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis
NCT03267277
CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)
NCT02858336
Environmental Risk Factors for Myositis in Military Personnel
NCT01734369
Genes Associated With Bronchopulmonary Dysplasia and Retinopathy of Prematurity
NCT01780155
The COX-2 Gene and the Immune System
NCT01678222
Environmental Polymorphisms Registry Health and Exposures Survey
NCT01688986
Bisphenol A Controlled Exposure Study
NCT01573429
Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage
NCT01143519
Hormonal Regulation of Puberty and Fertility
NCT01511588
TGF-(Beta) and Susceptibility to RSV
NCT01224691
Blood Vessel Study
NCT01524549
Agricultural Health Study Follow-up
NCT01399411
The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease
NCT01143493
A Follow-up of the Early Pregnancy Study Cohort.
NCT01132924
Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing
NCT01087307
Indoor Woodsmoke PM and Asthma
NCT00807183
Functional Implications of TNF
NCT00729131
Lung Mucus Hypersecretion and NQO1
NCT00729352
Biomarker Analysis of Stress
NCT00527384
PCOS Twin Study - Environmental Factors in the Development of Polycystic Ovary Syndrome, Phase 2
NCT00444288
Oral Bacteria and Allergic Disease in Children
NCT00438646
Children With Asthma in New Orleans After Hurricane Katrina
NCT00426634
The Influence of Breast Cancer Risk and Risk Perception on Lifestyle Behaviors Among Women With a Family History: A Mixed Method Approach
NCT00393406
Confirmation of Self-Reported Incident ALS Cases in the AARP-Diet and Health (AARP-DH) Cohort
NCT00377351
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 5 |
| Phase 3 | 3 |
Therapeutic Areas
What the Pipeline for National Institute of Environmental Health Sciences (NIEHS) Shows
According to the ClinicalTrials.gov registry, National Institute of Environmental Health Sciences (NIEHS) is linked to 145 US clinical trials across every stage of research activity. Of those, 15 studies are currently recruiting, about 10% of the sponsor's indexed portfolio, and 124 are already marked complete, representing roughly 86% of the total.
The phase mix for National Institute of Environmental Health Sciences (NIEHS) reports 3 late-stage studies (Phase 3 and Phase 4 combined) and 7 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for National Institute of Environmental Health Sciences (NIEHS) is Asthma with 8 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.