National Institute of Environmental Health Sciences (NIEHS)

75 total trials 42 currently recruiting 31 completed

Trial Pipeline

RECRUITING Phase 2

H01 in Adults With Interstitial Lung Disease (The SOLIS Study)

NCT06325696

RECRUITING

NIEHS Repository of Stored Biological Samples for Future Use

NCT05666739

RECRUITING

Observation of Environment and Reproductive-Endocrine Effects

NCT06280807

RECRUITING

Women s Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) Equity

NCT04983251

RECRUITING

Natural History of the Human Biological Response to Environmental Exposure and Injury

NCT04888923

RECRUITING

Reproductive Axis Maturation in the Early Post-Menarchal Years

NCT03986021

RECRUITING

Investigating the Impact of Obesity on Pubertal Development in Girls

NCT02583646

RECRUITING

NHALES (Natural History of Asthma With Longitudinal Environmental Sampling)

NCT02327897

RECRUITING

Study of the Effect of Innate on the Inflammatory Response to Endotoxin

NCT01143480

RECRUITING

Inherited Reproductive Disorders

NCT01500447

RECRUITING

Environmental Risk Factors for the Anti-synthetase Syndrome

NCT01276470

RECRUITING

Personalized Environment and Genes Study

NCT00341237

RECRUITING

Immune Cell Response to Stimuli

NCT00397280

RECRUITING

Adult and Juvenile Myositis

NCT00017914

ACTIVE NOT RECRUITING

Factors Influencing Fertility or Pregnancy Health

NCT04595760

ACTIVE NOT RECRUITING

Gulf Long-Term Follow-Up Study

NCT01287000

COMPLETED Phase 2

The Investigation of Vitamin D and Menstrual Cycles Trial, the inVitD Trial: A Phase II Clinical Trial

NCT05050916

COMPLETED

Qualitative Assessment of the Work-Sleep Relationship

NCT03389828

COMPLETED

Environmental Polymorphisms Registry Health and Exposures Survey

NCT01688986

COMPLETED

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

NCT01143519

COMPLETED

Blood Vessel Study

NCT01524549

COMPLETED

Functional Implications of TNF

NCT00729131

COMPLETED

Oral Bacteria and Allergic Disease in Children

NCT00438646

COMPLETED

Confirmation of Self-Reported Incident ALS Cases in the AARP-Diet and Health (AARP-DH) Cohort

NCT00377351

COMPLETED

Prospective Lung Transplant Database for Genetic Research

NCT00339209

COMPLETED

Children's Exposures/Health Effects/Diesel Exhaust

NCT00527345

COMPLETED

Disease Progression and Activity in Patients With Systemic Lupus Erythematosus

NCT00339261

COMPLETED

Study of Families With Twins or Siblings Discordant for Rheumatic Disorders

NCT00055055

COMPLETED

Effect of Environmental Exposures on the Egg Fertilizing Ability of Human Sperm

NCT00012480

COMPLETED

Work and Health Disparities Among Rural Women

NCT00042419

COMPLETED

Early Life Factors and Respiratory Health in Mexico City Children

NCT00342758

COMPLETED

Identifying Residential Hazards Using Home Test Kits

NCT00285532

COMPLETED

Outdoor Allergen Exposure, Sensitivity, and Acute Asthma

NCT00043992

COMPLETED NA

The Genetics of Environmental Asthma

NCT00018096

COMPLETED

Socio-economic Status and Age-related Disability in a Biracial Community

NCT00042133

COMPLETED

Pesticide Exposure Pathways for Farmworker Children

NCT00013754

COMPLETED

Vulnerability of the Fetus/Infant to PAH, PM2.5 AND ETS.

NCT00044603

COMPLETED

Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes

NCT00011713

COMPLETED

Fluorescence Bronchoscopy and Molecular Characterization of Abnormal Bronchial Lesions: Novel Approaches for Early Detection of Lung Cancer in High Risk Patients

NCT00512642

COMPLETED

Attention Deficit Disorder and Exposure to Lead

NCT00014898

COMPLETED

Pesticide Exposure and Health Status in North Carolina African American Male Farmers and Farm Workers

NCT00341965

COMPLETED

Air Pollution and Implantable Cardioverter Defibrillators

NCT00015574

COMPLETED

Bladder Cancer Case Control Study of Arsenic in Water

NCT00011518

COMPLETED

Early Exposure to Lead and Adolescent Development

NCT00011674

COMPLETED

Pesticides--Health Fertility and Reproductive Risk

NCT00015561

COMPLETED

Dichloroacetate Kinetics, Metabolism and Toxicology

NCT00015015

COMPLETED

Mechanisms of Inflammatory Liver Injury

NCT00011284

Phase Distribution

PhaseTrial count
Phase 2 2

What the Pipeline for National Institute of Environmental Health Sciences (NIEHS) Shows

According to the ClinicalTrials.gov registry, National Institute of Environmental Health Sciences (NIEHS) is linked to 75 US clinical trials across every stage of research activity. Of those, 42 studies are currently recruiting — about 56% of the sponsor's indexed portfolio — and 31 are already marked complete, representing roughly 41% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for National Institute of Environmental Health Sciences (NIEHS) reports 0 late-stage studies (Phase 3 and Phase 4 combined) and 2 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for National Institute of Environmental Health Sciences (NIEHS) is Asthma with 8 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial