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2026 data Public-data reference. official source

Anaplastic Large Cell Lymphoma

Open-data reference.

25 US clinical trials · 5 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 60 participants

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

Fred Hutchinson Cancer Center

NCT04195633

RECRUITING Phase 1 60 participants

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

National Cancer Institute (NCI)

NCT07055477

RECRUITING Phase 1 30 participants

A Study of Alectinib and Duvelisib in People With Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma (ALK+ALCL)

Memorial Sloan Kettering Cancer Center

NCT07001384

RECRUITING Phase 1 21 participants

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

Mayo Clinic

NCT06508463

RECRUITING Phase 1 20 participants

Azacitidine and Abatacept in Relapsed or Refractory T-Cell Lymphoma

National Cancer Institute (NCI)

NCT07388563

ACTIVE NOT RECRUITING NA 565 participants

Cholecalciferol in Improving Survival in Patients With Newly Diagnosed Cancer With Vitamin D Insufficiency

Mayo Clinic

NCT01787409

ACTIVE NOT RECRUITING Phase 2 30 participants

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

Northwestern University

NCT02232516

ACTIVE NOT RECRUITING Phase 1 21 participants

Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma

Tessa Therapeutics

NCT04526834

ACTIVE NOT RECRUITING Phase 1 13 participants

Pembrolizumab and Pralatrexate in Treating Patients With Relapsed or Refractory Peripheral T-Cell Lymphomas

City of Hope Medical Center

NCT03598998

ACTIVE NOT RECRUITING Phase 1 6 participants

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

Washington University School of Medicine

NCT05377827

COMPLETED Phase 1 124 participants

Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma

Mayo Clinic

NCT00918333

COMPLETED Phase 2 111 participants

Iodine I 131 Tositumomab, Etoposide and Cyclophosphamide Followed by Autologous Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Fred Hutchinson Cancer Center

NCT00073918

COMPLETED Phase 2 77 participants

Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

University of Chicago

NCT01839916

COMPLETED Phase 2 60 participants

Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma

National Cancer Institute (NCI)

NCT01258998

COMPLETED Phase 1 43 participants

Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors

National Cancer Institute (NCI)

NCT01326702

COMPLETED Phase 2 41 participants

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Mayo Clinic

NCT01261247

COMPLETED Early Phase 1 33 participants

Dose Monitoring of Busulfan and Combination Chemotherapy in Hodgkin or Non-Hodgkin Lymphoma Undergoing Stem Cell Transplant

Case Comprehensive Cancer Center

NCT01959477

COMPLETED Phase 1 29 participants

Vorinostat, Rituximab, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Lymphoma or Previously Untreated T-Cell Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

University of Washington

NCT00601718

COMPLETED Phase 1 23 participants

Safety Study of XmAb®2513 to Treat Hodgkin Lymphoma or Anaplastic Large Cell Lymphoma

Xencor

NCT00606645

COMPLETED Phase 1 21 participants

Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer

Fred Hutchinson Cancer Center

NCT00006251

COMPLETED Phase 1 20 participants

Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies

Case Comprehensive Cancer Center

NCT01658319

COMPLETED Phase 1 15 participants

Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

University of Nebraska

NCT01336920

COMPLETED Phase 2 14 participants

Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma

National Cancer Institute (NCI)

NCT00131937

COMPLETED Phase 1 12 participants

FAU in Treating Patients With Advanced Solid Tumors or Lymphoma

National Cancer Institute (NCI)

NCT00769288

COMPLETED Phase 1 8 participants

Bortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

Pierluigi Porcu

NCT01129180

Phase Distribution

PhaseTrial count
Early Phase 1 17
Phase 2 7

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Anaplastic Large Cell Lymphoma Trial Landscape

ClinicalTrials.gov lists 25 US studies indexed under Anaplastic Large Cell Lymphoma, and 5 of those are currently open to recruitment — roughly 20% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Anaplastic Large Cell Lymphoma shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 24 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Anaplastic Large Cell Lymphoma is led by National Cancer Institute (NCI) with 6 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 25 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Anaplastic Large Cell Lymphoma?

PlainTrial tracks 25 US clinical trials for Anaplastic Large Cell Lymphoma, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Anaplastic Large Cell Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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