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Atherosclerosis: full-pipeline trial registry
16 of 70 indexed Atherosclerosis trials are currently recruiting.
Corpus placement: #198 of 28,707 conditions by registered trial count.
70 US clinical trials · 16 currently recruiting · #198 of 28,707 conditions by registered trial count
Atherosclerosis: 70 US clinical trials tracked, 16 recruiting.
Atherosclerosis is the subject of 70 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 12 of these trials.
Enrollment posture brief
Registry condition atherosclerosis
OPEN 16 | RECR 23% | LATE 13 | EARLY 15 | RANK #198 | SPON 12
Volume-matched condition peers
Nearest open-share peer: Gout (23% recruiting · 35 trials)
Atherosclerosis lists 16 open slots (23% of 70 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Atherosclerosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Atherosclerosis is recruiting below its size-band peers.
16 of 70 indexed trials (22.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Atherosclerosis research.
National Heart, Lung, and Blood Institute (NHLBI) accounts for 12 of 70 trials (17.1%). 44 distinct sponsors appear on at least one study for this condition label.
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Typical Atherosclerosis enrolment sits around 216 participants.
Median target enrolment is 216 among the 70 trials that report a genuine target (sentinel values excluded). 18 of those (25.7%) plan for fewer than 100 participants.
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Atherosclerosis splits between interventional and observational designs.
43 interventional and 27 observational studies make up this index (61.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
70 total, page 1 of 2
Investigation of Metformin in Pre-Diabetes on Atherosclerotic Cardiovascular OuTcomes
VA Office of Research and Development
NCT02915198
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
National Heart, Lung, and Blood Institute (NHLBI)
NCT01143454
New Heart Imaging Techniques to Evaluate Possible Heart Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT01399385
Causes and Natural History of Dyslipidemias
National Heart, Lung, and Blood Institute (NHLBI)
NCT00353782
Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions
National Heart, Lung, and Blood Institute (NHLBI)
NCT06676046
Study of the Effect of Innate on the Inflammatory Response to Endotoxin
National Institute of Environmental Health Sciences (NIEHS)
NCT01143480
Text Education About Cardiovascular Health and HIV (TEACH-HIV)
University of California, San Francisco
NCT05642858
Machine Learning for Handheld Vascular Studies
Duke University
NCT02932176
Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial
Wake Forest University Health Sciences
NCT06488105
Cholesterol and Inflammation Lowering Via Bempedoic Acid, an ACL-inhibiting Regimen in HIV Trial (CLEAR HIV Trial)
Priscilla Hsue, MD
NCT05488431
Effect of Tirzepatide on Progression of Coronary Atherosclerosis Using MDCT
Matthew J. Budoff
NCT05708859
Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History
University of Southern California
NCT05867381
The Effect of Mindfulness on Vascular Inflammation in Stable Coronary Disease
Massachusetts General Hospital
NCT04505865
PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]
Johns Hopkins University
NCT05994014
Pilot Study Evaluating the Impact of Stress Reduction on Atherosclerotic : Heart and Mind Study
Massachusetts General Hospital
NCT04496947
High Protein Diet and Atherosclerosis
University of Missouri-Columbia
NCT05235464
Bogalusa Heart Study
Tulane University
NCT00005129
The Jackson Heart Study of Cardiovascular Disease Among African Americans
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005485
IMPact on Revascularization Outcomes of IVUS Guided Treatment of Complex Lesions and Economic Impact
Medstar Health Research Institute
NCT04221815
Mediators of Atherosclerosis in South Asians Living in America
University of California, San Francisco
NCT01207167
Century Trial, a Randomized Lifestyle Modification Study for Management of Stable Coronary Artery Disease
The University of Texas Health Science Center, Houston
NCT00756379
Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration
Massachusetts General Hospital
NCT04523194
Advancing Postmenopausal Preventive Therapy
University of Southern California
NCT04103476
Leucine, MTOR and Athero
University of Missouri-Columbia
NCT05470218
Action to Control Cardiovascular Risk in Diabetes (ACCORD)
National Heart, Lung, and Blood Institute (NHLBI)
NCT00000620
Understanding the Genetic and Hereditary Basis of Atherosclerosis
Wake Forest University Health Sciences
NCT00344292
Genetic Factors in Atherosclerosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00359307
12-week Open-label, Phase IIIb Comparing Efficacy and Safety of Rosuvastatin (CRESTOR™) in Combination With Ezetimibe
AstraZeneca
NCT00525824
PLATINUM Diversity
Boston Scientific Corporation
NCT02240810
Non-Invasive Imaging of Atherosclerosis
Icahn School of Medicine at Mount Sinai
NCT01418313
Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery
Unity Health Toronto
NCT03900026
Examining the Genetic Predictors of Coronary Artery Calcification in African Americans
University of Michigan
NCT00925561
RANGER™ Paclitaxel Coated Balloon vs Standard Balloon Angioplasty
Boston Scientific Corporation
NCT03064126
Improving Cardiovascular Risk Prediction Using Hand Held Carotid Ultrasonography Study
University of Wisconsin, Madison
NCT00574457
VEAPS: Vitamin E Atherosclerosis Prevention Study
National Institute on Aging (NIA)
NCT00114387
The OMEGA Clinical Trial
Boston Scientific Corporation
NCT01419171
Plaque Inflammation and Dysfunctional HDL in AIM-HIGH
University of Washington
NCT00880178
Testosterone Replacement in Older Men and Atherosclerosis Progression
Brigham and Women's Hospital
NCT00287586
Safety and Efficacy Study of Ad2/Hypoxia Inducible Factor (HIF)-1α/VP16 Gene Transfer in Patients With Intermittent Claudication
Genzyme, a Sanofi Company
NCT00117650
Effects of Worksite Wellness Interventions on Vascular Function, Insulin Sensitivity and High-Density Lipoprotein in Overweight or Obese Women
National Heart, Lung, and Blood Institute (NHLBI)
NCT00666172
MARS - Monitored Atherosclerosis Regression Study
Merck Sharp & Dohme
NCT00116870
Evaluation of the Efficacy and Safety of Bempedoic Acid (ETC-1002) as Add-on to Ezetimibe Therapy in Patients With Elevated LDL-C (CLEAR Tranquility)
Esperion Therapeutics
NCT03001076
The Role of microRNA-210 in Regulating Oxidative Stress in Patients With PAD
University of West Florida
NCT04089943
Randomized Trial of Imaging Versus Risk Factor-Based Therapy for Plaque Regression
National Heart, Lung, and Blood Institute (NHLBI)
NCT01212900
New Technologies to Determine Carotid Plaque Vulnerability
Mayo Clinic
NCT02224339
Study of the Interaction Between the Cells Lining Blood Vessels and Angiotensin-Converting Enzyme
National Heart, Lung, and Blood Institute (NHLBI)
NCT00001461
Comparing TR Band to Statseal in Conjunction With TR Band
VA Long Beach Healthcare System
NCT03028025
A Web-based Approach to Treating Cardiovascular Disease Risk in Employees With Metabolic Syndrome
Baptist Health South Florida
NCT01912209
Individualized Comprehensive Atherosclerosis Risk-reduction Evaluation Program
Piedmont Healthcare
NCT00969865
Effects of Highly Active Anti-Retroviral Therapy on Cardiovascular Health in Infants of HIV-Infected Mothers
University of Miami
NCT00253682
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 11 |
| Phase 3 | 5 |
| Phase 4 | 8 |
Top Sponsors
Named interventions
Most-linked intervention names on Atherosclerosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Atherosclerosis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Atherosclerosis page
70 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 16 Atherosclerosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Heart, Lung, and Blood Institute (NHLBI) sponsors the most Atherosclerosis trials on record, review their full trial history before evaluating a specific study. See National Heart, Lung, and Blood Institute (NHLBI)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Atherosclerosis condition card totals 70 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.