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NCT06676046 · ClinicalTrials.gov registry record
Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions
A clinical trial of Atherosclerosis and Dyslipidemia, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- Recruiting
- Registry status
- 1,500
- Enrollment target
- 1
- Study location
NCT06676046: Recruiting study of Atherosclerosis and Dyslipidemia, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
NCT06676046 is a study of Atherosclerosis and Dyslipidemia that is actively recruiting participants, run by National Heart, Lung, and Blood Institute (NHLBI). The registered enrollment target is 1,500 participants, above the 1,044-participant average among 69 other Atherosclerosis trials with a reported enrollment target (44% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06676046, a study of Atherosclerosis and Dyslipidemia, is actively recruiting participants, sponsored by National Heart, Lung, and Blood Institute (NHLBI).
- RECRUITING
- Registry status
- 1,500 participants
- Enrollment target
- 1
- Study location
Study Summary
Background: The right amount of fats in the blood (cholesterol and triglycerides) are a key part of a healthy organism. Too much or too little of these fats may manifest as diseases (dyslipidemia). There are many causes for these abnormalities, but some are genetically determined and we would like to better understand the progression of these conditions over time. Objective: This natural history study aims to learn more about dyslipidemias; how they change over time; and how they respond to therapy. We also want to develop new diagnosis methods for these conditions. With the knowledge we will acquire we hope to provide new insights, new approaches and improve the overall health of these patients. Eligibility: Individuals aged 10 years and older, residing both within and outside the United States, who have or are suspected of having a disorder that causes changes in the levels of fats in their blood (genetic dyslipidemias). Design: Participants residing within and outside the United States will be screened. Their medical records may be reviewed. They may talk to researchers about their medical history by phone, telehealth, or in person. All study visits are optional. Participants may visit the NIH up to 15 times per year, if needed. Each visit may include a physical exam and blood tests. Participants may also have an electrocardiogram (EKG). The EKG measures the electrical activity when the heart beats. In some cases, participants may remain in the study for up to 20 years.
Primary Outcome
To observe change overtime in low-density lipoprotein cholesterol (LDL-C).
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,500 participants |
| Start Date | 2025-01-15 |
| Est. Completion | 2044-11-24 |
What NCT06676046 shows while recruiting
NCT06676046 is an observational study that tracks outcomes without assigning an intervention. Its 1,500 participants enrollment target places it among the larger protocols in the corpus, above the 1,044-participant average among 69 other Atherosclerosis trials with a reported enrollment target (44% higher).
The record links to 2 conditions, with Atherosclerosis appearing as the primary indexed condition, and to 0 interventions.
NCT06676046 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT06676046 about?
NCT06676046 is a clinical study titled "Natural History of Uncommon Dyslipidemias, Rare Lipid Disorders and Unusual Atherosclerotic Conditions". Background: The right amount of fats in the blood (cholesterol and triglycerides) are a key part of a healthy organism. Too much or too little of these fats may manifest as diseases (dyslipidemia). There are many causes for these abnormalities, but some are genetically determined and we would like ...
What is the current status of trial NCT06676046?
This trial is currently recruiting. The enrollment target is 1,500 participants. The study started on 2025-01-15. Estimated completion is 2044-11-24.
What conditions does trial NCT06676046 study?
This clinical trial studies the following conditions: Atherosclerosis, Dyslipidemia.
Who is sponsoring clinical trial NCT06676046?
This trial is sponsored by National Heart, Lung, and Blood Institute (NHLBI), which has 501 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06676046 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Atherosclerosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06676046's enrollment target sits among peer trials
1,500 14th of 69 higher than 56 of 69 other Atherosclerosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atherosclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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