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NCT05867381 · ClinicalTrials.gov registry record · NA

Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History

A NA study of Atherosclerosis and Air Pollution, sponsored by University of Southern California.

Recruiting
Registry status
NA
Development phase
112
Enrollment target
1
Study location

NCT05867381: Recruiting NA study of Atherosclerosis and Air Pollution, sponsored by University of Southern California.

NCT05867381 is a NA study of Atherosclerosis and Air Pollution that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 112 participants, below the 1,064-participant average among 69 other Atherosclerosis trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05867381, a NA study of Atherosclerosis and Air Pollution, is actively recruiting participants, sponsored by University of Southern California.

RECRUITING
Registry status
NA
Development phase
112 participants
Enrollment target
1
Study location

Study Summary

This double-blind, randomized, crossover trial aims to test the hypothesis that longer-term indoor air filtration intervention can slow atherothrombosis progression by reducing indoor fine particulate matter (PM2.5) exposure in adults with ischemic heart disease history.

Primary Outcome

Differences between baseline and systolic and diastolic blood pressure measured during and after intervention

Interventions

  • DEVICE HEPA filtration
  • DEVICE Sham filtration

Study Locations (1)

California

  • Keck School of Medicine, University of Southern California - Los Angeles

Trial Details

FieldValue
Enrollment Target 112 participants
Start Date 2023-07-11
Est. Completion 2027-06-30
Phase NA
University of Southern California

617 total trials

What NCT05867381 shows while recruiting

NCT05867381 is an interventional study that assigns participants to a tested intervention. The registered 112 participants enrollment target is mid-sized for trials with a published cap, below the 1,064-participant average among 69 other Atherosclerosis trials with a reported enrollment target (89% lower).

The record links to 2 conditions, with Atherosclerosis appearing as the primary indexed condition, and to 2 interventions - of which HEPA filtration is the first listed.

NCT05867381 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT05867381 about?

NCT05867381 is a clinical study titled "Using Indoor Air Filtration to Slow Atherothrombosis Progression in Adults With Ischemic Heart Disease History". This double-blind, randomized, crossover trial aims to test the hypothesis that longer-term indoor air filtration intervention can slow atherothrombosis progression by reducing indoor fine particulate matter (PM2.5) exposure in adults with ischemic heart disease history.

What is the current status of trial NCT05867381?

This trial is currently recruiting. It is a NA study. The enrollment target is 112 participants. The study started on 2023-07-11. Estimated completion is 2027-06-30.

What conditions does trial NCT05867381 study?

This clinical trial studies the following conditions: Atherosclerosis, Air Pollution.

What interventions are being tested in trial NCT05867381?

The interventions under investigation include: HEPA filtration (DEVICE), Sham filtration (DEVICE).

Who is sponsoring clinical trial NCT05867381?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05867381 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Atherosclerosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT05867381's enrollment target sits among peer trials

112 49th of 69 higher than 21 of 69 other Atherosclerosis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Atherosclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05867381, the US trial registry maintained by the National Library of Medicine. NCT05867381 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.