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ClinicalTrials.gov 16 recruiting now full pipeline

Atherosclerosis: full-pipeline trial registry

16 of 70 indexed Atherosclerosis trials are currently recruiting.

Corpus placement: #198 of 28,707 conditions by registered trial count.

70 US clinical trials · 16 currently recruiting · #198 of 28,707 conditions by registered trial count

Atherosclerosis: 70 US clinical trials tracked, 16 recruiting.

Atherosclerosis is the subject of 70 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 12 of these trials.

Enrollment posture brief

Registry condition atherosclerosis

OPEN 16 | RECR 23% | LATE 13 | EARLY 15 | RANK #198 | SPON 12

Nearest open-share peer: Gout (23% recruiting · 35 trials)

Metastatic Castration-Resist64.3%Brain Tumor47.9%Kidney Cancer27.5%Atherosclerosis (this)23%Healthy Subjects20%
Open-enrollment share among volume-matched conditions near Atherosclerosis

Atherosclerosis lists 16 open slots (23% of 70 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Atherosclerosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Atherosclerosis is recruiting below its size-band peers.

    16 of 70 indexed trials (22.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Atherosclerosis research.

    National Heart, Lung, and Blood Institute (NHLBI) accounts for 12 of 70 trials (17.1%). 44 distinct sponsors appear on at least one study for this condition label.

  3. Typical Atherosclerosis enrolment sits around 216 participants.

    Median target enrolment is 216 among the 70 trials that report a genuine target (sentinel values excluded). 18 of those (25.7%) plan for fewer than 100 participants.

  4. Atherosclerosis splits between interventional and observational designs.

    43 interventional and 27 observational studies make up this index (61.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 211Phase 35Phase 48

Open and recent trials

70 total, page 2 of 2

COMPLETED 162 participants

Carotid Atherosclerotic Plaque Study

University of Wisconsin, Madison

NCT00214006

COMPLETED 150 participants

Pilot Study of Ultrasonic Determined Carotid Plaque Composition

D. Geoffrey Vince

NCT01879397

COMPLETED Phase 3 145 participants

High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly

Johns Hopkins University

NCT00127218

COMPLETED 120 participants

Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk

National Heart, Lung, and Blood Institute (NHLBI)

NCT00613158

COMPLETED 108 participants

Racial Differences in Control of Blood Vessel Tone and Blood Flow

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001747

COMPLETED 100 participants

Magnetic Resonance Angiography (MRA) for the Diagnosis of Atherosclerosis

National Institutes of Health Clinical Center (CC)

NCT00001841

COMPLETED 100 participants

Distributed Registry

Stanford University

NCT03898570

COMPLETED Phase 1 88 participants

Single and Multiple Ascending Doses of MEDI6570 in Subjects With Type 2 Diabetes Mellitus

MedImmune

NCT03654313

COMPLETED Phase 2 83 participants

An Imaging Study in Patients With Atherosclerosis Taking Rilapladib or Placebo for 12 Weeks

GlaxoSmithKline

NCT00695305

COMPLETED Phase 1 81 participants

A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation

Indiana University

NCT02685098

COMPLETED Phase 2 80 participants

Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001890

COMPLETED Phase 4 70 participants

Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome

Florida Atlantic University

NCT00272311

COMPLETED 59 participants

11C-PIB PET Study in MESA at Columbia University

José A. Luchsinger

NCT03981380

COMPLETED Phase 2 58 participants

Inflammation and Vascular Function in Atherosclerosis

Brigham and Women's Hospital

NCT00760019

COMPLETED 35 participants

PET/CT Imaging Companion Study To ACTG A5314

Massachusetts General Hospital

NCT02312219

COMPLETED Phase 4 34 participants

Pharmacogenomics of Antiplatelet Response

Johns Hopkins University

NCT02234427

COMPLETED NA 27 participants

Local Paclitaxel Delivery for SFA Disease

University of Oklahoma

NCT00821028

COMPLETED Phase 2 25 participants

Effects of Angiotensin-Converting Enzyme Inhibitor (Ramipril) Therapy on Blood Vessel Inflammation

National Heart, Lung, and Blood Institute (NHLBI)

NCT00005928

COMPLETED Phase 1 24 participants

Study to Evaluate Darapladib in Moderately Hepatically Impaired Subjects

GlaxoSmithKline

NCT01154114

COMPLETED Phase 1 5 participants

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque

Massachusetts General Hospital

NCT01873716

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Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 11
Phase 3 5
Phase 4 8

Named interventions

Most-linked intervention names on Atherosclerosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
Placebo Other
4 trials
Bempedoic acid Drug
2 trials
Stress Reduction Behavioral
2 trials
Ezetimibe Drug
2 trials
Simvastatin Drug
2 trials
Aspirin Drug
2 trials
Paclitaxel Drug
2 trials

US sites by state

Facility locations filed on Atherosclerosis trials. A trial with sites in several states counts in each.

Maryland 21 trials
California 19 trials
Florida 11 trials
Massachusetts 10 trials
Texas 8 trials
Illinois 8 trials
North Carolina 7 trials
Minnesota 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Atherosclerosis page

70 registered trials, 16 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Atherosclerosis condition card totals 70 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.