Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 16 recruiting now official registry

Atherosclerosis clinical trials

16 of 70 indexed Atherosclerosis trials are currently recruiting.

70 US clinical trials · 16 currently recruiting

Atherosclerosis is the subject of 70 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 12 of these trials.

The research picture

Atherosclerosis has 70 registered US clinical trials, 16 of them open to new participants right now, about 23% of the total.

16
recruiting participants now
23%
of trials open to enrollment
13
in Phase 3–4 (later-stage)
12
top sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Phase 14Phase 211Phase 35Phase 48

Active & Recent Trials

70 total, page 2 of 2

COMPLETED 162 participants

Carotid Atherosclerotic Plaque Study

University of Wisconsin, Madison

NCT00214006

COMPLETED 150 participants

Pilot Study of Ultrasonic Determined Carotid Plaque Composition

D. Geoffrey Vince

NCT01879397

COMPLETED Phase 3 145 participants

High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly

Johns Hopkins University

NCT00127218

COMPLETED 120 participants

Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk

National Heart, Lung, and Blood Institute (NHLBI)

NCT00613158

COMPLETED 108 participants

Racial Differences in Control of Blood Vessel Tone and Blood Flow

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001747

COMPLETED 100 participants

Magnetic Resonance Angiography (MRA) for the Diagnosis of Atherosclerosis

National Institutes of Health Clinical Center (CC)

NCT00001841

COMPLETED 100 participants

Distributed Registry

Stanford University

NCT03898570

COMPLETED Phase 1 88 participants

Single and Multiple Ascending Doses of MEDI6570 in Subjects With Type 2 Diabetes Mellitus

MedImmune

NCT03654313

COMPLETED Phase 2 83 participants

An Imaging Study in Patients With Atherosclerosis Taking Rilapladib or Placebo for 12 Weeks

GlaxoSmithKline

NCT00695305

COMPLETED Phase 1 81 participants

A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation

Indiana University

NCT02685098

COMPLETED Phase 2 80 participants

Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections

National Heart, Lung, and Blood Institute (NHLBI)

NCT00001890

COMPLETED Phase 4 70 participants

Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome

Florida Atlantic University

NCT00272311

COMPLETED 59 participants

11C-PIB PET Study in MESA at Columbia University

José A. Luchsinger

NCT03981380

COMPLETED Phase 2 58 participants

Inflammation and Vascular Function in Atherosclerosis

Brigham and Women's Hospital

NCT00760019

COMPLETED 35 participants

PET/CT Imaging Companion Study To ACTG A5314

Massachusetts General Hospital

NCT02312219

COMPLETED Phase 4 34 participants

Pharmacogenomics of Antiplatelet Response

Johns Hopkins University

NCT02234427

COMPLETED NA 27 participants

Local Paclitaxel Delivery for SFA Disease

University of Oklahoma

NCT00821028

COMPLETED Phase 2 25 participants

Effects of Angiotensin-Converting Enzyme Inhibitor (Ramipril) Therapy on Blood Vessel Inflammation

National Heart, Lung, and Blood Institute (NHLBI)

NCT00005928

COMPLETED Phase 1 24 participants

Study to Evaluate Darapladib in Moderately Hepatically Impaired Subjects

GlaxoSmithKline

NCT01154114

COMPLETED Phase 1 5 participants

Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque

Massachusetts General Hospital

NCT01873716

← Previous Page 2 of 2

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 11
Phase 3 5
Phase 4 8

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Atherosclerosis Trial Landscape

70 indexed Atherosclerosis studies · 16 recruiting (23%).

Phase mix: 13 late (III/IV) vs 15 early (I/II).

Top sponsor: National Heart, Lung, and Blood Institute (NHLBI) (12 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Atherosclerosis?

PlainTrial tracks 70 US clinical trials for Atherosclerosis, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Atherosclerosis?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.