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Atherosclerosis clinical trials
16 of 70 indexed Atherosclerosis trials are currently recruiting.
70 US clinical trials · 16 currently recruiting
Atherosclerosis is the subject of 70 registered US clinical trials on ClinicalTrials.gov, 16 of them currently open to new participants. 13 are in Phase 3-4 (later-stage) and 15 in Phase 1-2 (earlier-stage). The most active sponsor is National Heart, Lung, and Blood Institute (NHLBI), running 12 of these trials.
The research picture
Atherosclerosis has 70 registered US clinical trials, 16 of them open to new participants right now, about 23% of the total.
- 16
- recruiting participants now
- 23%
- of trials open to enrollment
- 13
- in Phase 3–4 (later-stage)
- 12
- top sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Active & Recent Trials
70 total, page 2 of 2
Carotid Atherosclerotic Plaque Study
University of Wisconsin, Madison
NCT00214006
Pilot Study of Ultrasonic Determined Carotid Plaque Composition
D. Geoffrey Vince
NCT01879397
High-Density Lipoprotein (HDL) Cholesterol Increased Plaque Stabilization in the Elderly
Johns Hopkins University
NCT00127218
Using Differences in Peripheral Blood Leukocyte Gene Expression to Determine Cardiovascular Disease Risk
National Heart, Lung, and Blood Institute (NHLBI)
NCT00613158
Racial Differences in Control of Blood Vessel Tone and Blood Flow
National Heart, Lung, and Blood Institute (NHLBI)
NCT00001747
Magnetic Resonance Angiography (MRA) for the Diagnosis of Atherosclerosis
National Institutes of Health Clinical Center (CC)
NCT00001841
Distributed Registry
Stanford University
NCT03898570
Single and Multiple Ascending Doses of MEDI6570 in Subjects With Type 2 Diabetes Mellitus
MedImmune
NCT03654313
An Imaging Study in Patients With Atherosclerosis Taking Rilapladib or Placebo for 12 Weeks
GlaxoSmithKline
NCT00695305
A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation
Indiana University
NCT02685098
Effects of Hormone Therapy on the Immune Systems of Postmenopausal Women With Chronic Infections
National Heart, Lung, and Blood Institute (NHLBI)
NCT00001890
Aspirin Dose and Atherosclerosis in Patients With Metabolic Syndrome
Florida Atlantic University
NCT00272311
11C-PIB PET Study in MESA at Columbia University
José A. Luchsinger
NCT03981380
Inflammation and Vascular Function in Atherosclerosis
Brigham and Women's Hospital
NCT00760019
PET/CT Imaging Companion Study To ACTG A5314
Massachusetts General Hospital
NCT02312219
Pharmacogenomics of Antiplatelet Response
Johns Hopkins University
NCT02234427
Local Paclitaxel Delivery for SFA Disease
University of Oklahoma
NCT00821028
Effects of Angiotensin-Converting Enzyme Inhibitor (Ramipril) Therapy on Blood Vessel Inflammation
National Heart, Lung, and Blood Institute (NHLBI)
NCT00005928
Study to Evaluate Darapladib in Moderately Hepatically Impaired Subjects
GlaxoSmithKline
NCT01154114
Indocyanine Green Fluorescence Uptake in Human Carotid Artery Plaque
Massachusetts General Hospital
NCT01873716
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 11 |
| Phase 3 | 5 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Atherosclerosis Trial Landscape
70 indexed Atherosclerosis studies · 16 recruiting (23%).
Phase mix: 13 late (III/IV) vs 15 early (I/II).
Top sponsor: National Heart, Lung, and Blood Institute (NHLBI) (12 trials), 9 others listed. 20 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Atherosclerosis?
PlainTrial tracks 70 US clinical trials for Atherosclerosis, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Atherosclerosis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.