Medical Information Only. Consult your healthcare provider before enrolling in any clinical trial.
Clinical trials in Minnesota
1,633 of 4,506 in-state trials are recruiting (36%); roughly in line with the 37% national average.
According to ClinicalTrials.gov-derived indexes, Minnesota sits in the upper half of US states by in-state trial count (#15 of 52 states by registered in-state trial count).
Minnesota: 4,506 US clinical trials with in-state sites, 1,633 recruiting.
Minnesota has 4,506 registered US clinical trials with a study site in-state, 1,633 of them currently recruiting (roughly in line with the 37% national average). 688 of these trials are in Phase 3 (late-stage) and 981 in Phase 2. The most frequently studied condition in Minnesota is Healthy, with 73 linked trials.
Mid-pack research density
Minnesota sits in the upper half of the state corpus, so volume is meaningful but not hub-scale. Use condition and sponsor rollups below to see what drives the in-state mix.
In-line with national open share
Minnesota tracks 4,506 in-state trials with 1,633 open (36%), roughly in line with the 37% national average within about 1-2 points of the 37% national figure.
- 36%
- open (near national share)
- 1,633
- recruiting participants now
- 688
- Phase 3 (late-stage)
- 73
- top: Healthy
Recruiting share is roughly in line with the 37% national average. Counts include every study with at least one recorded site in the state. Registry reference only, not medical advice.
Minnesota vs all states by indexed in-state trial count
Where this state's ClinicalTrials.gov site count sits among every state with at least one listed trial (coverage density, not care quality)
4,506 Top 29% more indexed trials than 71% of 52 states
States, banded by indexed in-state trial count
Each bar is a band; taller bars hold more states. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov · 2026-08-08
Key findings
What ClinicalTrials.gov does not surface for Minnesota on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Minnesota open-enrollment share matches the national baseline.
1,633 of 4,506 in-state trials (36.2%) are recruiting, against 37% nationally (-0.8 percentage points). Counts include every study with at least one recorded site in the state.
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Minnesota trial sites spread across 8 city hubs.
Rochester lists 2,246 of 4,506 in-state trials (49.8%) across 226 named facilities. Cities need five or more listed trials to appear here; locations are as filed by sponsors.
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Healthy is the most-studied condition in Minnesota.
73 of 4,506 in-state trials (1.6%) list Healthy. That is a local concentration figure, not a national disease ranking.
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One sponsor accounts for a large share of Minnesota trials.
Mayo Clinic appears on 859 of 4,506 in-state trials (19.1%). Sponsor identity is as filed on ClinicalTrials.gov.
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1,919 Minnesota trials carry a completed status.
1,919 of 4,506 (42.6%) are completed. The open share above is the remainder that still lists recruiting.
By Status
| Status | Trial count |
|---|---|
| Completed | 1,919 |
| Recruiting | 1,633 |
| Active | 954 |
By Phase
| Phase | Trial count |
|---|---|
| NA | 1,090 |
| Phase 2 | 981 |
| Phase 1 | 701 |
| Phase 3 | 688 |
| Phase 4 | 165 |
| Early Phase 1 | 45 |
Top Conditions
Top Sponsors
Where trials run in Minnesota
Rochester carries 2,246 of Minnesota's 4,506 indexed trials (50%) across 226 named sites, ahead of Minneapolis at 1,738. 8 cities clear five listed trials, together naming 1,037 distinct sites.
| City | Trials | Listed sites |
|---|---|---|
| Rochester | 2,246 | 226 |
| Minneapolis | 1,738 | 519 |
| Saint Paul | 252 | 123 |
| Saint Louis Park | 95 | 49 |
| Edina | 66 | 46 |
| Duluth | 66 | 29 |
| Fridley | 49 | 18 |
| Plymouth | 44 | 27 |
Distinct trials and named sites per city, as filed with ClinicalTrials.gov; cities under five trials omitted. Vintage 2026-08-08.
Trial size large
Minnesota's in-state trials target 40,937 patients on average (p98 by trial size among 52 states with enrollment data), larger, multi-site studies than most states.
Minnesota: in-state trial volume sits in the high tercile
Sites spread across 8 cities with five or more listed trials, led by Rochester (2,246, 50% of the state total) and Minneapolis (1,738), together naming 1,037 distinct research locations.
Phase mix: 688 Phase 3 vs 981 Phase 2 (balanced across stages).
Top condition: Healthy (73 trials); top sponsor Mayo Clinic (859).
high-volume · high-open figures (4,506 trials · 36% open) describe registry geography under the trial size large read, not clinic capacity or protocol fit. Confirm status on ClinicalTrials.gov before acting.
States near Minnesota on in-state trial volume
Cross-state peers under the trial size large read (high-volume · high-open), not the same-state browse list.
Similar high-volume hubs (± open share)
Similar high-open peers (± trial volume)
- West Virginia · 36% recruiting · 277 trials
- Massachusetts · 35% recruiting · 7,667 trials
- Wyoming · 35% recruiting · 17 trials
- Ohio · 35% recruiting · 6,514 trials
- Wisconsin · 37% recruiting · 1,760 trials