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NCT01399385 · ClinicalTrials.gov registry record · NA

New Heart Imaging Techniques to Evaluate Possible Heart Disease

A NA study of Healthy and Obesity, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Recruiting
Registry status
NA
Development phase
4,000
Enrollment target
1
Study location

NCT01399385: Recruiting NA study of Healthy and Obesity, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

NCT01399385 is a NA study of Healthy and Obesity that is actively recruiting participants, run by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). The registered enrollment target is 4,000 participants, above the 644-participant average among 1,090 other Healthy trials with a reported enrollment target (521% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01399385, a NA study of Healthy and Obesity, is actively recruiting participants, sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

RECRUITING
Registry status
NA
Development phase
4,000 participants
Enrollment target
1
Study location

Study Summary

Background: \- Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. Better MRI methods are needed to improve heart disease diagnosis, especially by avoiding the use of radiation. Researchers are testing new techniques to improve the quality of heart MRI, compared with more complex studies like catheterization or angiography. Objectives: \- To compare heart MRI techniques with other tests used to diagnose heart disease. Eligibility: \- People at least 18 years of age who either have or may have heart disease, or are healthy volunteers. Design: * Participants will be screened with a physical exam, medical history, and blood tests. * They will have an angiography to study the inside of blood vessels. This test is an x-ray study of the blood vessels. It will be done either separately or as part of a set of tests to diagnose possible heart disease. * Participants will have at least one and up to five MRI scans. The scans will involve different methods of studying the heart and blood vessels. Participants may also have a computed tomography scan to confirm the findings of an MRI scan. * No treatment will be provided as part of this protocol.

Primary Outcome

The accelerated High-resolution MRA results will be compared to conventional angiography and/or computerized tomography angiography (CTA). High- resolution lumen dimensions will be compared to black- blood lumen measurements as well. It is expected that the MRA findings from the 3T scanner will demonstrate image quality that is nearly equivalent to the quality of the coronary arteries visualized using CTA and/or conventional coronary catheterization. Three- dimensional arterial dilatation mappin

Conditions Studied

Healthy Obesity Diabetes Healthy Volunteers Atherosclerosis

Interventions

  • DEVICE MR Imaging Techniques - 1
  • DEVICE MR Imaging Techniques - 2
  • DEVICE MR Imaging Techniques - 3
  • DEVICE MR Imaging Techniques - 4

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center - Bethesda

Trial Details

FieldValue
Enrollment Target 4,000 participants
Start Date 2011-07-06
Est. Completion 2030-11-05
Phase NA
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

490 total trials

What NCT01399385 shows while recruiting

NCT01399385 is an interventional study that assigns participants to a tested intervention. Its 4,000 participants enrollment target places it among the larger protocols in the corpus, above the 644-participant average among 1,090 other Healthy trials with a reported enrollment target (521% higher).

The record links to 5 conditions, with Healthy appearing as the primary indexed condition, and to 4 interventions - of which MR Imaging Techniques - 1 is the first listed.

NCT01399385 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT01399385 about?

NCT01399385 is a clinical study titled "New Heart Imaging Techniques to Evaluate Possible Heart Disease". Background: \- Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other condition...

What is the current status of trial NCT01399385?

This trial is currently recruiting. It is a NA study. The enrollment target is 4,000 participants. The study started on 2011-07-06. Estimated completion is 2030-11-05.

What conditions does trial NCT01399385 study?

This clinical trial studies the following conditions: Healthy, Obesity, Diabetes, Healthy Volunteers, Atherosclerosis.

What interventions are being tested in trial NCT01399385?

The interventions under investigation include: MR Imaging Techniques - 1 (DEVICE), MR Imaging Techniques - 2 (DEVICE), MR Imaging Techniques - 3 (DEVICE), MR Imaging Techniques - 4 (DEVICE).

Who is sponsoring clinical trial NCT01399385?

This trial is sponsored by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), which has 490 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01399385 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01399385's enrollment target sits among peer trials

4,000 16th of 1090 higher than 1,075 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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More recruiting context for NCT01399385

Source: ClinicalTrials.gov NCT01399385, the US trial registry maintained by the National Library of Medicine. NCT01399385 (large enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.