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NCT00116870 · ClinicalTrials.gov registry record · Phase 2

MARS - Monitored Atherosclerosis Regression Study

A Phase 2 study of Coronary Artery Disease and Atherosclerosis, sponsored by Merck Sharp & Dohme.

Completed
Registry status
Phase 2
Development phase
270
Enrollment target
1
Study location

NCT00116870 is a Phase 2 study of Coronary Artery Disease and Atherosclerosis that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 270 participants, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (79% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT00116870, a Phase 2 study of Coronary Artery Disease and Atherosclerosis, has completed, sponsored by Merck Sharp & Dohme.

COMPLETED
Registry status
Phase 2
Development phase
270 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to determine whether significant alterations in serum lipoproteins as provided by the drug lovastatin can substantially reduce atherosclerosis progression or even induce regression.

Interventions

  • DRUG lovastatin

Study Locations (1)

California

  • Atherosclerosis Research Unit, Division of Cardiovascular Medicine, Department of Medicine - Los Angeles

Trial Details

FieldValue
Enrollment Target 270 participants
Start Date 1985-06
Est. Completion 1992-02
Phase Phase 2

Sponsor

Merck Sharp & Dohme

558 total trials

What the Registry Record Tells You About NCT00116870

The ClinicalTrials.gov registry entry for NCT00116870 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 270 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,286-participant average among 219 other Coronary Artery Disease trials with a reported enrollment target (79% lower). The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Coronary Artery Disease appearing as the primary indexed condition, and to 1 intervention - of which lovastatin is the first listed.

NCT00116870 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT00116870 about?

NCT00116870 is a clinical study titled "MARS - Monitored Atherosclerosis Regression Study". The purpose of this study is to determine whether significant alterations in serum lipoproteins as provided by the drug lovastatin can substantially reduce atherosclerosis progression or even induce regression.

What is the current status of trial NCT00116870?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 270 participants. The study started on 1985-06. Estimated completion is 1992-02.

What conditions does trial NCT00116870 study?

This clinical trial studies the following conditions: Coronary Artery Disease, Atherosclerosis.

What interventions are being tested in trial NCT00116870?

The interventions under investigation include: lovastatin (DRUG).

Who is sponsoring clinical trial NCT00116870?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00116870 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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