University of Missouri-Columbia
Trial Pipeline
Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease
NCT07478172
Carbo-fix Lateral Plate Devices and Standard Plate-Nail Constructs in Distal Femur Fractures
NCT07280169
Impact of Phenylalanine Elevations on Brain and Cognition in Adult PKU Carriers
NCT07220265
Effects of Grape Consumption on the Immune-Gut Axis in Obesity
NCT07231484
Pars Healing on MRI
NCT07215845
Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)
NCT07329257
7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
NCT07175077
Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass
NCT07227493
Growth Hormone Resistance of Beta-cells
NCT06571487
Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
NCT06689618
Growth Hormone Resistance of Beta-cells in Women and People
NCT06571500
Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms
NCT06787066
Intrauterine Device Insertion Pain Management
NCT06951191
Examining the Role of Executive Functioning in Family-Based Intensive Health Behavior and Lifestyle Treatment
NCT06969235
Brain Blood Flow and Lactate in Non-obese and Obese Subjects
NCT06791837
Propranolol in Primary Progressive Aphasia
NCT06066710
Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)
NCT06741735
Improving Participation After Stroke Self-Management-Rehabilitation
NCT06588647
Cognitive Rehabilitation Following Breast Cancer Treatment
NCT06545045
Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria
NCT06560736
NeuroControl of Nicotine Dependence
NCT06347055
Early Neurovascular Adaptations in Aging Women
NCT06520982
Empagliflozin Reversal of Arterial StiffnEss in Aging
NCT06506422
Remote Sensing for ADRD-Specific Activities Identification in Older Adults
NCT07120347
Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome
NCT06433115
Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia
NCT06417177
Baker Gordon Syndrome Natural History Study
NCT06399952
Accelerated ART Initiation for PWHIV Who Are Out of Care
NCT06374758
Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure
NCT06845735
Sleep as a Mechanism of Change in Alcohol Use
NCT06286774
Impact GLP-1 Agonists Following Bariatric
NCT06132477
CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)
NCT05846399
Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Myasthenia Gravis
NCT06064695
Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.
NCT05846438
Sex Disparities in Hypoxic Vasodilation and Impact of Obesity
NCT05219799
High Protein Diet and Atherosclerosis
NCT05235464
Lipoprotein Kinetics in T1D
NCT05179954
Skin Preparation for Elective Foot and Ankle Surgery
NCT05401292
Dietary Fiber Effects on the Microbiome and Satiety
NCT04611217
Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer
NCT04444869
Targeting Insomnia in School Aged Children With Autism Spectrum Disorder
NCT04545606
Membrane Target Detection for Leukemia Treatment
NCT04841447
Smoking Cessation Behavioral Treatment Study
NCT03948893
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy
NCT04182997
Animal and Plant Proteins and Glucose Metabolism
NCT03994367
An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction
NCT03713424
Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)
NCT03652753
Outcomes of Low-Impact Exercise Program for People With Ankle, Knee, and/or Hip Pain
NCT03711773
Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair
NCT03610763
Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers
NCT02838836
Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow
NCT03551951
Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia
NCT06998238
This Study Consists of Two Study Parts Conducted Under a Single IRB. Part I: Short Term ApoE-dependent Cerebral Blood Flow Response to Sirolimus in Cognitively Normal Adults Part II: Short Term ApoE-dependent Cerebral Blood Flow and Lung Perfusion Response to Sirolimus in Cognitively Normal Adults
NCT05386914
ADAM17 and Vascular Function in Diabetes
NCT04557228
Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants
NCT07043712
Leucine, MTOR and Athero
NCT05470218
Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity
NCT04436731
Sleep Intervention for Chronic Insomnia Using Virtual Reality Pilot Study
NCT04253691
Study of Fat Tissue's Ability to Take up Sugar in the Obese Population
NCT02994459
Opioid Rapid Response System: Naloxone Training in Communities
NCT06238128
Cognitive Rehabilitation in Post-COVID-19 Syndrome
NCT06136871
Adaptation and Implementation of a Cherokee-based Participatory Research Project to Reduce CVD Risk
NCT06671652
The Drinking Dashboard Study
NCT05630625
Sleep Restriction and Postprandial Lipemia
NCT05713370
Variability in Microbial Response to Dietary Fiber
NCT06023940
Cognitive Training in Mild Cognitive Impairment
NCT04899089
Experience With a Pediatric Summer Intensive Therapy Program
NCT04891328
A Randomized Trial of Exparel vs Saline in Opioid Reduction of Pain Management Following Lumbar Spine Surgeries.
NCT04644796
Remote Neurocognitive and Psychological Assessment in PKU
NCT04943393
Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome
NCT04681742
Open Label Study: Treatment of ALS Fatigue With PolyMVA
NCT04557410
Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty
NCT04415931
Perioperative Pregabalin in Ureteroscopy
NCT04122196
COVID-19 in Patients With HIV
NCT04333953
Examining the Effects of Neural Stimulation on Inhibitory Control and Cigarette Smoking
NCT03960138
Maintenance Transcranial Magnetic Stimulation in Major Depressive Disorder
NCT04076644
The Use of Intranasal Calcitonin to Improve Pain and Activity in Elderly Pelvic Ring Injuries
NCT03812991
Weight Stigma Effect on Neural Control of Appetite
NCT03934424
The Effect of Kombucha on Blood Sugar Levels in Humans
NCT04051294
Indications for Osteochondral Allograft Transplantation
NCT03711747
Alcohol Impaired Driving: From the Laboratory to the Natural Environment
NCT03846050
Sex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric Acid
NCT03648996
Radiofrequency Chip for Localization of Non-Palpable Breast Lesions
NCT03684408
Sleep, Exercise and Insulin Sensitivity
NCT03556410
Insomnia Treatment and Problems (the iTAP Study)
NCT03627832
Feasibility of the Lee Silverman Voice Treatment®-BIG Intervention in Stroke
NCT03602443
Taste Changes With Bariatric Surgery
NCT03548038
Intratympanic Steroid for Bell's Palsy
NCT03508440
Sleep and Pain Intervention for Chronic Widespread Pain Pilot Study
NCT02688569
Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response
NCT02871349
Improving the Management of Chronic Pain in Primary Care
NCT02783365
Comparison of BioCartilage Versus Marrow Stimulating Procedure for Cartilage Defects of the Knee
NCT02203071
Study to Compare Negative Pressure Wound Therapy or Standard Dressings After Orthopedic Surgery
NCT02064270
Hemostasis in Open Acetabulum and Pelvic Ring Surgery Using Tranexamic Acid
NCT02051686
The Beneficial Effects of Healthy Snacks on Appetite Control, Satiety, and Reward-driven Eating Behavior in Young People
NCT01781286
Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults
NCT01227330
Using Health Information Technology (HIT) to Improve Ambulatory Chronic Disease Care: Smart Device Substudy
NCT00802152
Incisional Vacuum Assisted Closure (IVAC) Device and Its Effect on Implanted Bone Morphogenic Protein (BMP-2)
NCT00829621
Medication Adherence in Hypertension Study
NCT00688350
Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence
NCT00734968
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 10 |
| Phase 2 | 37 |
| Phase 3 | 1 |
| Phase 4 | 37 |
Therapeutic Areas
What the Pipeline for University of Missouri-Columbia Shows
According to the ClinicalTrials.gov registry, University of Missouri-Columbia is linked to 275 US clinical trials across every stage of research activity. Of those, 222 studies are currently recruiting — about 81% of the sponsor's indexed portfolio — and 45 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for University of Missouri-Columbia reports 38 late-stage studies (Phase 3 and Phase 4 combined) and 47 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for University of Missouri-Columbia is Obesity with 8 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.