University of Missouri-Columbia

275 total trials 222 currently recruiting 45 completed

Trial Pipeline

RECRUITING NA

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

NCT07478172

RECRUITING NA

Carbo-fix Lateral Plate Devices and Standard Plate-Nail Constructs in Distal Femur Fractures

NCT07280169

RECRUITING NA

Impact of Phenylalanine Elevations on Brain and Cognition in Adult PKU Carriers

NCT07220265

RECRUITING NA

Effects of Grape Consumption on the Immune-Gut Axis in Obesity

NCT07231484

RECRUITING NA

Pars Healing on MRI

NCT07215845

RECRUITING

Investigating Phenotypic, Epigenetic, and NeuroGenetic Traits in Rare and Ultra-rare Neurodevelopmental Disorders (Project PENGUIN)

NCT07329257

RECRUITING

7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)

NCT07175077

RECRUITING

Open Pilon With FIBERGRAFT AERIDYAN Matrix Bioactive Glass

NCT07227493

RECRUITING

Growth Hormone Resistance of Beta-cells

NCT06571487

RECRUITING NA

Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults

NCT06689618

RECRUITING

Growth Hormone Resistance of Beta-cells in Women and People

NCT06571500

RECRUITING Early Phase 1

Sympathetic Vascular Transduction Across the Menopause Transition: Contributing Mechanisms

NCT06787066

RECRUITING Phase 4

Intrauterine Device Insertion Pain Management

NCT06951191

RECRUITING NA

Examining the Role of Executive Functioning in Family-Based Intensive Health Behavior and Lifestyle Treatment

NCT06969235

RECRUITING

Brain Blood Flow and Lactate in Non-obese and Obese Subjects

NCT06791837

RECRUITING Early Phase 1

Propranolol in Primary Progressive Aphasia

NCT06066710

RECRUITING NA

Study of Fetal Health Outcomes: Working With a Missouri E-telehealth Platform (The SHOW-ME Study)

NCT06741735

RECRUITING NA

Improving Participation After Stroke Self-Management-Rehabilitation

NCT06588647

RECRUITING NA

Cognitive Rehabilitation Following Breast Cancer Treatment

NCT06545045

RECRUITING NA

Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria

NCT06560736

RECRUITING NA

NeuroControl of Nicotine Dependence

NCT06347055

RECRUITING Early Phase 1

Early Neurovascular Adaptations in Aging Women

NCT06520982

RECRUITING Phase 2

Empagliflozin Reversal of Arterial StiffnEss in Aging

NCT06506422

RECRUITING NA

Remote Sensing for ADRD-Specific Activities Identification in Older Adults

NCT07120347

RECRUITING NA

Effects of Lean Beef Consumption on Cardiometabolic Health and Gut Microbiome

NCT06433115

RECRUITING Early Phase 1

Impact of Early Aging and Menopause on the Vascular Responses to Hypoxia

NCT06417177

RECRUITING

Baker Gordon Syndrome Natural History Study

NCT06399952

RECRUITING Phase 4

Accelerated ART Initiation for PWHIV Who Are Out of Care

NCT06374758

RECRUITING NA

Absorbable vs Non-Absorbable Sutures for Hip Capsular Closure

NCT06845735

RECRUITING NA

Sleep as a Mechanism of Change in Alcohol Use

NCT06286774

RECRUITING Phase 4

Impact GLP-1 Agonists Following Bariatric

NCT06132477

RECRUITING Phase 4

CAT BITE Antibiotic Prophylaxis for the Hand/Forearm (CATBITE)

NCT05846399

RECRUITING NA

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Myasthenia Gravis

NCT06064695

RECRUITING NA

Effect of Drain Care on Infection Rate and Quality of Life in Implant-Based Breast Reconstruction.

NCT05846438

RECRUITING Early Phase 1

Sex Disparities in Hypoxic Vasodilation and Impact of Obesity

NCT05219799

RECRUITING NA

High Protein Diet and Atherosclerosis

NCT05235464

RECRUITING NA

Lipoprotein Kinetics in T1D

NCT05179954

RECRUITING Phase 4

Skin Preparation for Elective Foot and Ankle Surgery

NCT05401292

RECRUITING NA

Dietary Fiber Effects on the Microbiome and Satiety

NCT04611217

RECRUITING Phase 2

Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal Cancer

NCT04444869

RECRUITING NA

Targeting Insomnia in School Aged Children With Autism Spectrum Disorder

NCT04545606

RECRUITING

Membrane Target Detection for Leukemia Treatment

NCT04841447

RECRUITING NA

Smoking Cessation Behavioral Treatment Study

NCT03948893

RECRUITING Phase 4

Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy

NCT04182997

RECRUITING NA

Animal and Plant Proteins and Glucose Metabolism

NCT03994367

RECRUITING Phase 2

An fMRI Study of the Effects of Clavulanic Acid on Drug Addiction

NCT03713424

RECRUITING Phase 4

Pilon Fracture With Intra-articular Injection of N-Acetylcysteine (Pilon NAC)

NCT03652753

RECRUITING NA

Outcomes of Low-Impact Exercise Program for People With Ankle, Knee, and/or Hip Pain

NCT03711773

RECRUITING NA

Harnessing Neuroplasticity to Enhance Functional Recovery During Chronic Recovery From Upper Extremity Nerve Repair

NCT03610763

RECRUITING

Tumor Cell and DNA Detection in the Blood, Urine and Bone Marrow of Patients With Solid Cancers

NCT02838836

RECRUITING

Tumor Cell and DNA Detection in the Blood, Urine, and Bone Marrow

NCT03551951

ACTIVE NOT RECRUITING NA

Evaluating the Influence of Diet-induced Weight Loss on Fat (Adipose) Tissue's Insulin Sensitivity and Testosterone Synthesis in Women With Overweight or Obesity, Insulin Resistance, and Hyperandrogenemia

NCT06998238

ACTIVE NOT RECRUITING Phase 1

This Study Consists of Two Study Parts Conducted Under a Single IRB. Part I: Short Term ApoE-dependent Cerebral Blood Flow Response to Sirolimus in Cognitively Normal Adults Part II: Short Term ApoE-dependent Cerebral Blood Flow and Lung Perfusion Response to Sirolimus in Cognitively Normal Adults

NCT05386914

ACTIVE NOT RECRUITING NA

ADAM17 and Vascular Function in Diabetes

NCT04557228

ACTIVE NOT RECRUITING NA

Effects of Pulse Consumption, Gut Microbiome, and Appetite in Healthy Participants

NCT07043712

ACTIVE NOT RECRUITING NA

Leucine, MTOR and Athero

NCT05470218

ACTIVE NOT RECRUITING Early Phase 1

Sex Disparities in Hypoxic Sympatholysis and Impact of Obesity

NCT04436731

ACTIVE NOT RECRUITING NA

Sleep Intervention for Chronic Insomnia Using Virtual Reality Pilot Study

NCT04253691

ACTIVE NOT RECRUITING

Study of Fat Tissue's Ability to Take up Sugar in the Obese Population

NCT02994459

COMPLETED NA

Opioid Rapid Response System: Naloxone Training in Communities

NCT06238128

COMPLETED NA

Cognitive Rehabilitation in Post-COVID-19 Syndrome

NCT06136871

COMPLETED NA

Adaptation and Implementation of a Cherokee-based Participatory Research Project to Reduce CVD Risk

NCT06671652

COMPLETED NA

The Drinking Dashboard Study

NCT05630625

COMPLETED NA

Sleep Restriction and Postprandial Lipemia

NCT05713370

COMPLETED NA

Variability in Microbial Response to Dietary Fiber

NCT06023940

COMPLETED NA

Cognitive Training in Mild Cognitive Impairment

NCT04899089

COMPLETED

Experience With a Pediatric Summer Intensive Therapy Program

NCT04891328

COMPLETED Phase 4

A Randomized Trial of Exparel vs Saline in Opioid Reduction of Pain Management Following Lumbar Spine Surgeries.

NCT04644796

COMPLETED

Remote Neurocognitive and Psychological Assessment in PKU

NCT04943393

COMPLETED NA

Feasibility Testing of Cognitive Strategy Training in Post-Concussive Syndrome

NCT04681742

COMPLETED Phase 1

Open Label Study: Treatment of ALS Fatigue With PolyMVA

NCT04557410

COMPLETED NA

Local Infiltration Analgesia Vs. Interscalene Block in Total Shoulder Arthorplasty

NCT04415931

COMPLETED Phase 2

Perioperative Pregabalin in Ureteroscopy

NCT04122196

COMPLETED

COVID-19 in Patients With HIV

NCT04333953

COMPLETED NA

Examining the Effects of Neural Stimulation on Inhibitory Control and Cigarette Smoking

NCT03960138

COMPLETED NA

Maintenance Transcranial Magnetic Stimulation in Major Depressive Disorder

NCT04076644

COMPLETED Phase 4

The Use of Intranasal Calcitonin to Improve Pain and Activity in Elderly Pelvic Ring Injuries

NCT03812991

COMPLETED NA

Weight Stigma Effect on Neural Control of Appetite

NCT03934424

COMPLETED NA

The Effect of Kombucha on Blood Sugar Levels in Humans

NCT04051294

COMPLETED

Indications for Osteochondral Allograft Transplantation

NCT03711747

COMPLETED NA

Alcohol Impaired Driving: From the Laboratory to the Natural Environment

NCT03846050

COMPLETED Phase 2

Sex-related Differences in Arterial Stiffness in Type 2 Diabetics: Role of Uric Acid

NCT03648996

COMPLETED NA

Radiofrequency Chip for Localization of Non-Palpable Breast Lesions

NCT03684408

COMPLETED NA

Sleep, Exercise and Insulin Sensitivity

NCT03556410

COMPLETED NA

Insomnia Treatment and Problems (the iTAP Study)

NCT03627832

COMPLETED NA

Feasibility of the Lee Silverman Voice Treatment®-BIG Intervention in Stroke

NCT03602443

COMPLETED

Taste Changes With Bariatric Surgery

NCT03548038

COMPLETED Phase 2

Intratympanic Steroid for Bell's Palsy

NCT03508440

COMPLETED NA

Sleep and Pain Intervention for Chronic Widespread Pain Pilot Study

NCT02688569

COMPLETED Early Phase 1

Trial of Propranolol in Children and Youth With Autism Spectrum Disorder and Predictors of Response

NCT02871349

COMPLETED NA

Improving the Management of Chronic Pain in Primary Care

NCT02783365

COMPLETED

Comparison of BioCartilage Versus Marrow Stimulating Procedure for Cartilage Defects of the Knee

NCT02203071

COMPLETED NA

Study to Compare Negative Pressure Wound Therapy or Standard Dressings After Orthopedic Surgery

NCT02064270

COMPLETED NA

Hemostasis in Open Acetabulum and Pelvic Ring Surgery Using Tranexamic Acid

NCT02051686

COMPLETED NA

The Beneficial Effects of Healthy Snacks on Appetite Control, Satiety, and Reward-driven Eating Behavior in Young People

NCT01781286

COMPLETED Phase 1

Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults

NCT01227330

COMPLETED NA

Using Health Information Technology (HIT) to Improve Ambulatory Chronic Disease Care: Smart Device Substudy

NCT00802152

COMPLETED NA

Incisional Vacuum Assisted Closure (IVAC) Device and Its Effect on Implanted Bone Morphogenic Protein (BMP-2)

NCT00829621

COMPLETED NA

Medication Adherence in Hypertension Study

NCT00688350

COMPLETED Phase 4

Does Treatment With Macrobid Reduce Urinary Tract Infections in Patients Receiving a Sub-Urethral Sling for Incontinence

NCT00734968

Phase Distribution

PhaseTrial count
Phase 1 10
Phase 2 37
Phase 3 1
Phase 4 37

What the Pipeline for University of Missouri-Columbia Shows

According to the ClinicalTrials.gov registry, University of Missouri-Columbia is linked to 275 US clinical trials across every stage of research activity. Of those, 222 studies are currently recruiting — about 81% of the sponsor's indexed portfolio — and 45 are already marked complete, representing roughly 16% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for University of Missouri-Columbia reports 38 late-stage studies (Phase 3 and Phase 4 combined) and 47 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for University of Missouri-Columbia is Obesity with 8 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial