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ClinicalTrials.gov 14 recruiting now early-phase tilt

Healthy Subjects: early-phase trial registry

14 of 70 indexed Healthy Subjects trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #198 of 28,707 conditions by registered trial count.

70 US clinical trials · 14 currently recruiting · #198 of 28,707 conditions by registered trial count

Healthy Subjects: 70 US clinical trials tracked, 14 recruiting.

Healthy Subjects is the subject of 70 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 50 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 7 of these trials.

Enrollment posture brief

Registry condition healthy-subjects

OPEN 14 | RECR 20% | LATE 1 | EARLY 50 | RANK #198 | SPON 7

Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (20% recruiting · 10 trials)

Metastatic Castration-Resist64.3%Brain Tumor47.9%Kidney Cancer27.5%Atherosclerosis22.9%Healthy Subjects (this)20%
Open-enrollment share among volume-matched conditions near Healthy Subjects

Healthy Subjects lists 14 open slots (20% of 70 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Healthy Subjects on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Healthy Subjects is recruiting below its size-band peers.

    14 of 70 indexed trials (20%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Healthy Subjects trials is spread across many organizations.

    GlaxoSmithKline accounts for 7 of 70 trials (10%). 48 distinct sponsors appear on at least one study for this condition label.

  3. Most Healthy Subjects trials plan to enrol fewer than 100 people.

    Median target enrolment is 32 among the 70 trials that report a genuine target (sentinel values excluded). 58 of those (82.9%) plan for fewer than 100 participants.

  4. Healthy Subjects research is mostly interventional.

    65 interventional and 5 observational studies make up this index (92.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 147Phase 23Phase 31

Open and recent trials

70 total, page 1 of 2

RECRUITING 700 participants

Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)

National Institute of Dental and Craniofacial Research (NIDCR)

NCT01568697

RECRUITING NA 400 participants

In-Person Recruitment of Individuals to the Alzheimer's Prevention Trial (APT) Webstudy

University of Southern California

NCT07218120

RECRUITING NA 300 participants

Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter

Arizona State University

NCT06181149

RECRUITING 215 participants

Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)

National Heart, Lung, and Blood Institute (NHLBI)

NCT02417714

RECRUITING NA 120 participants

The Short-term Verbal Memory Endophenotype for Developmental Language Disorder Language Disorder

Father Flanagan's Boys' Home

NCT06968169

RECRUITING NA 90 participants

Echography Study_Anthropometric Measurements

Crossject

NCT06279689

RECRUITING Phase 2 70 participants

A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1

Cerus Corporation

NCT07015437

RECRUITING Early Phase 1 60 participants

Single-tracer Multiparametric PET Imaging

University of California, Davis

NCT06014515

RECRUITING NA 40 participants

Optimizing Ultrasound-induced Anti-inflammation in Human Subjects

University of Virginia

NCT05685108

RECRUITING NA 30 participants

Avocado and Postprandial Responses

University of Vermont Medical Center

NCT06818032

RECRUITING Phase 1 24 participants

Phase I Study of ICP-332 in Healthy Subjects

InnoCare Pharma

NCT06530966

RECRUITING Phase 1 24 participants

Phase 1 Study of Intravaginal KB15A

ZabBio

NCT07222020

RECRUITING Phase 1 15 participants

A Study to Investigate HLA-G Targeted Exosome (SOB100) in Healthy Subjects

Shine-On Biomedical Co.

NCT07219940

RECRUITING Early Phase 1 6 participants

Radiocaine Safety Study In Healthy Human Subjects

Lutroo Imaging

NCT07081217

ACTIVE NOT RECRUITING NA 244 participants

Cerebral Cortical Influences on Autonomic Function

David Levinthal

NCT03869372

ACTIVE NOT RECRUITING NA 90 participants

A Music and Visual Arts Digital Intervention in Teenagers to Promote Healthy Engagement With Social Media.

New York University

NCT06402253

ACTIVE NOT RECRUITING NA 88 participants

Lysine-specific Demethylase 1 and Salt-sensitivity in Humans

Brigham and Women's Hospital

NCT03029806

ACTIVE NOT RECRUITING NA 64 participants

Training Effects on Fuel Metabolism

University of Minnesota

NCT02150889

ACTIVE NOT RECRUITING NA 42 participants

Metabolic Responses to Spermidine Supplementation.

Chrysea Labs Lda

NCT05459961

ACTIVE NOT RECRUITING NA 30 participants

Effect of Stimulation on the Vagus Nerve

Indiana University

NCT04206540

ACTIVE NOT RECRUITING Early Phase 1 10 participants

Methemoglobin Concentration in High Dose Inhaled Nitric Oxide

Massachusetts General Hospital

NCT05612074

COMPLETED Phase 1 3,052 participants

Autoinjector Device Assessment Study

AstraZeneca

NCT02349802

COMPLETED Phase 3 1,200 participants

Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Healthy Children Aged 15 Months to 17 Years

Pfizer

NCT00761631

COMPLETED Phase 1 164 participants

A Study of PF-06410293 Following Subcutaneous Administration Using A Prefilled Syringe Or A Prefilled Pen In Healthy Adult Subjects

Pfizer

NCT02572245

COMPLETED 152 participants

Brain-Computer Interface and Mind-Body Awareness Training

University of Minnesota

NCT02074722

COMPLETED Phase 1 146 participants

Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea

Eisai

NCT03471871

COMPLETED Phase 1 125 participants

A Phase 1 Study to Evaluate the Safety of MEDI7814 in Adult Volunteers

MedImmune

NCT01544361

COMPLETED NA 99 participants

hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects

Massachusetts General Hospital

NCT00742235

COMPLETED Phase 1 73 participants

Phase 1 Study of MGD010 in Healthy Subjects

MacroGenics

NCT02376036

COMPLETED Phase 1 72 participants

A Phase 1, Open-Label, 10 Day Safety Study

Trius Therapeutics LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT01623401

COMPLETED Phase 1 66 participants

A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted Conditions

Sanofi

NCT03776227

COMPLETED Phase 1 60 participants

Crossover Study to Evaluate the Effect of Lemborexant Versus Placebo and Zolpidem on Postural Stability, Auditory Awakening Threshold, and Cognitive Performance in Healthy Subjects 55 Years and Older

Eisai

NCT03008447

COMPLETED Phase 1 59 participants

A Study to Determine the Effect of a High-Fat Meal on the Rate and Extent of E2006 Absorption in Healthy Subjects

Eisai

NCT02089412

COMPLETED Phase 1 56 participants

Study of KBP-7072 in Healthy Male and Female Subjects

KBP Biosciences

NCT05507463

COMPLETED 50 participants

The Effects of Coffee

American University

NCT00336271

COMPLETED Phase 1 50 participants

Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects

Eisai

NCT03451110

COMPLETED Phase 1 48 participants

First-in-human Study to Assess Safety and Tolerability of a Single Subcutaneous Dose of SAR441255 in Lean to Overweight Subjects

Sanofi

NCT04521738

COMPLETED Phase 2 40 participants

A Study to Assess Recovery and Survival of Radiolabeled Apheresis Platelet Components Treated With the INTERCEPT Blood System for Platelets With LED Illuminator.

Cerus Corporation

NCT06697223

COMPLETED Phase 1 36 participants

Single and Multiple Dose Asian Bridging Study

Eisai

NCT01251731

COMPLETED NA 34 participants

Pea vs Whey Protein Supplementation With Resistance Training on Young Adults' Strength, Body Composition, and Metabolic Parameters

Texas Woman's University

NCT07420933

COMPLETED Phase 1 33 participants

Bioavailability and Food Effect Study of 3 Types of Carisbamate

SK Life Science

NCT04520360

COMPLETED Phase 1 32 participants

Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine

Dizal Pharmaceuticals

NCT05486949

COMPLETED Phase 1 32 participants

A Phase 1 Study of CDX-0159

Celldex Therapeutics

NCT04146129

COMPLETED Phase 1 32 participants

A Study to Evaluate a Single Intravenous (IV) Dose Using a New Manufactured Clone and Single Ascending Doses of Subcutaneous (SC) Injections

Astellas Pharma Global Development

NCT02150070

COMPLETED Phase 1 30 participants

Safety and Efficacy of Trans Sodium Crocetinate (TSC) in Enhancing Tissue Oxygen Levels in Healthy Volunteers

Diffusion Pharmaceuticals

NCT04808622

COMPLETED Phase 1 29 participants

Study to Evaluate the Effect of a Single Oral Dose of MT-7117 on the QT/QTc Interval in Healthy Subjects

Tanabe Pharma America

NCT05241535

COMPLETED Phase 1 28 participants

A Study to Compare to the Pharmacokinetic Profile of Two Paracetamol Formulations

GlaxoSmithKline

NCT01476189

COMPLETED Phase 1 28 participants

Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol®

GlaxoSmithKline

NCT01540734

COMPLETED Phase 1 28 participants

Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol® Extend

GlaxoSmithKline

NCT01540721

COMPLETED Phase 1 25 participants

A Multicenter, Open-label Study to Determine the Effects of Lacosamide on Sleep in Healthy Subjects

UCB Pharma

NCT01530386

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Phase Distribution

PhaseTrial count
Phase 1 47
Phase 2 3
Phase 3 1

Named interventions

Most-linked intervention names on Healthy Subjects records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
Marketed paracetamol Drug
3 trials
Experimental paracetamol formulation Drug
3 trials
ASP015K Drug
2 trials
Isavuconazole Drug
2 trials
HTBZ Drug
1 trials
PF-06882961 Immediate Release Solution Drug
1 trials
PF-06882961 Controlled Release Tablet (short) Drug
1 trials

US sites by state

Facility locations filed on Healthy Subjects trials. A trial with sites in several states counts in each.

Maryland 11 trials
Texas 9 trials
California 9 trials
New York 6 trials
Nebraska 6 trials
Virginia 5 trials
Ohio 5 trials
Florida 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Healthy Subjects page

70 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 14 Healthy Subjects trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • GlaxoSmithKline sponsors the most Healthy Subjects trials on record, review their full trial history before evaluating a specific study. See GlaxoSmithKline's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Healthy Subjects condition card totals 70 registered trials; most-linked intervention Placebo; top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.