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Healthy Subjects
Open-data reference.
70 US clinical trials · 14 currently recruiting
Active & Recent Trials
Oral Bacteria and Immune System Problems Involved in Gum Disease (Periodontitis)
National Institute of Dental and Craniofacial Research (NIDCR)
NCT01568697
In-Person Recruitment of Individuals to the Alzheimer's Prevention Trial (APT) Webstudy
University of Southern California
NCT07218120
Auditory Prediction and Error Evaluation in the Speech of Individuals Who Stutter
Arizona State University
NCT06181149
Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)
National Heart, Lung, and Blood Institute (NHLBI)
NCT02417714
The Short-term Verbal Memory Endophenotype for Developmental Language Disorder Language Disorder
Father Flanagan's Boys' Home
NCT06968169
Echography Study_Anthropometric Measurements
Crossject
NCT06279689
A Recovery and Lifespan Study Using INTERCEPT Red Blood Cells Prepared Using the INTERCEPT Blood System for RBCs With AS-1
Cerus Corporation
NCT07015437
Single-tracer Multiparametric PET Imaging
University of California, Davis
NCT06014515
Optimizing Ultrasound-induced Anti-inflammation in Human Subjects
University of Virginia
NCT05685108
Avocado and Postprandial Responses
University of Vermont Medical Center
NCT06818032
Phase I Study of ICP-332 in Healthy Subjects
InnoCare Pharma
NCT06530966
Phase 1 Study of Intravaginal KB15A
ZabBio
NCT07222020
A Study to Investigate HLA-G Targeted Exosome (SOB100) in Healthy Subjects
Shine-On Biomedical Co.
NCT07219940
Radiocaine Safety Study In Healthy Human Subjects
Lutroo Imaging
NCT07081217
Cerebral Cortical Influences on Autonomic Function
David Levinthal
NCT03869372
A Music and Visual Arts Digital Intervention in Teenagers to Promote Healthy Engagement With Social Media.
New York University
NCT06402253
Lysine-specific Demethylase 1 and Salt-sensitivity in Humans
Brigham and Women's Hospital
NCT03029806
Training Effects on Fuel Metabolism
University of Minnesota
NCT02150889
Metabolic Responses to Spermidine Supplementation.
Chrysea Labs Lda
NCT05459961
Effect of Stimulation on the Vagus Nerve
Indiana University
NCT04206540
Methemoglobin Concentration in High Dose Inhaled Nitric Oxide
Massachusetts General Hospital
NCT05612074
Autoinjector Device Assessment Study
AstraZeneca
NCT02349802
Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Healthy Children Aged 15 Months to 17 Years
Pfizer
NCT00761631
A Study of PF-06410293 Following Subcutaneous Administration Using A Prefilled Syringe Or A Prefilled Pen In Healthy Adult Subjects
Pfizer
NCT02572245
Brain-Computer Interface and Mind-Body Awareness Training
University of Minnesota
NCT02074722
Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea
Eisai
NCT03471871
A Phase 1 Study to Evaluate the Safety of MEDI7814 in Adult Volunteers
MedImmune
NCT01544361
hCAP18 Levels and Vitamin D Deficiency in Healthy Subjects
Massachusetts General Hospital
NCT00742235
Phase 1 Study of MGD010 in Healthy Subjects
MacroGenics
NCT02376036
A Phase 1, Open-Label, 10 Day Safety Study
Trius Therapeutics LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
NCT01623401
A Bioequivalence Study Testing Two Formulations of Sotagliflozin in Healthy Male and Female Subjects Under Fasted Conditions
Sanofi
NCT03776227
Crossover Study to Evaluate the Effect of Lemborexant Versus Placebo and Zolpidem on Postural Stability, Auditory Awakening Threshold, and Cognitive Performance in Healthy Subjects 55 Years and Older
Eisai
NCT03008447
A Study to Determine the Effect of a High-Fat Meal on the Rate and Extent of E2006 Absorption in Healthy Subjects
Eisai
NCT02089412
Study of KBP-7072 in Healthy Male and Female Subjects
KBP Biosciences
NCT05507463
The Effects of Coffee
American University
NCT00336271
Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects
Eisai
NCT03451110
First-in-human Study to Assess Safety and Tolerability of a Single Subcutaneous Dose of SAR441255 in Lean to Overweight Subjects
Sanofi
NCT04521738
A Study to Assess Recovery and Survival of Radiolabeled Apheresis Platelet Components Treated With the INTERCEPT Blood System for Platelets With LED Illuminator.
Cerus Corporation
NCT06697223
Single and Multiple Dose Asian Bridging Study
Eisai
NCT01251731
Pea vs Whey Protein Supplementation With Resistance Training on Young Adults' Strength, Body Composition, and Metabolic Parameters
Texas Woman's University
NCT07420933
Bioavailability and Food Effect Study of 3 Types of Carisbamate
SK Life Science
NCT04520360
Drug-drug Interactions Between AZD4205 and Itraconazole/Carbamazepine
Dizal Pharmaceuticals
NCT05486949
A Phase 1 Study of CDX-0159
Celldex Therapeutics
NCT04146129
A Study to Evaluate a Single Intravenous (IV) Dose Using a New Manufactured Clone and Single Ascending Doses of Subcutaneous (SC) Injections
Astellas Pharma Global Development
NCT02150070
Safety and Efficacy of Trans Sodium Crocetinate (TSC) in Enhancing Tissue Oxygen Levels in Healthy Volunteers
Diffusion Pharmaceuticals
NCT04808622
Study to Evaluate the Effect of a Single Oral Dose of MT-7117 on the QT/QTc Interval in Healthy Subjects
Tanabe Pharma America
NCT05241535
A Study to Compare to the Pharmacokinetic Profile of Two Paracetamol Formulations
GlaxoSmithKline
NCT01476189
Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol®
GlaxoSmithKline
NCT01540734
Pharmacokinetic Study Investigating the Extent of Paracetamol Absorption From a New Formulation of Paracetamol Compared With Panadol® Extend
GlaxoSmithKline
NCT01540721
A Multicenter, Open-label Study to Determine the Effects of Lacosamide on Sleep in Healthy Subjects
UCB Pharma
NCT01530386
A Single Oral Dose Study to Compare the Bioavailability Between Two Different Tablet Formulations and Assess if There is a Food Effect With the New Formulation
Astellas Pharma
NCT01484964
A Study to Evaluate the Effect of Verapamil on the Pharmacokinetics of ASP015K in Healthy Adult Subjects
Astellas Pharma Global Development
NCT02111317
A Study to Evaluate the Effect of Multiple Doses of Isavuconazole on the Pharmacokinetics of Repaglinide and Caffeine
Astellas Pharma Global Development
NCT02128321
A Study to Evaluate the Effect of Multiple Doses of Esomeprazole on the Pharmacokinetics of Isavuconazole
Astellas Pharma Global Development
NCT02128893
Multiple Dose Study Evaluating the Safety and Tolerability of NSA-789
Wyeth is now a wholly owned subsidiary of Pfizer
NCT00795730
Effect of a Commercial Cosmetic Mouth Rinse on Plaque Re-growth
GlaxoSmithKline
NCT01122862
Effects of Systemically Administered Hydrocortisone on the Immune System in Healthy Volunteers
National Heart, Lung, and Blood Institute (NHLBI)
NCT01281995
A Drug-Drug Interaction Study to Evaluate the Effect of Rifampin on the Pharmacokinetics of Apremilast
Amgen
NCT01561963
GSK1349572 First Time in Human Study
GlaxoSmithKline
NCT00555035
Drug-Interaction Study to Evaluate the Effect of Rifampin, a Potent CYP3A4 Inducer, on the Systemic Exposure of Pacritinib in Healthy Subjects
CTI BioPharma
NCT02807116
Relative Bioavailability Study of Two New Dolutegravir/Abacavir/Lamivudine Fixed Dose Combination Tablets
ViiV Healthcare
NCT01366547
Effect of Oral Adenosine-triphosphate (ATP) on Human Muscle Performance
Metabolic Technologies
NCT01141504
Evaluate Retention of an Orally Administered Device Using Gamma Scintigraphy
Procter and Gamble
NCT00754091
A Study to Examine the Absorption of GSK561679 in Healthy Male Volunteers
GlaxoSmithKline
NCT00539136
DDI Study of Etravirine and GSK1265744
GlaxoSmithKline
NCT00920296
A Single Dose Crossover Study In Healthy Subjects To Evaluate Different Formulations Of PF-06882961
Pfizer
NCT03492697
Study to Evaluate the Pharmacokinetics of 14C-labeled Isavuconazole Following a Single Oral Dose of 14C-labeled Prodrug Isavuconazonium Sulfate (BAL8557) in Healthy Male Subjects
Astellas Pharma Global Development
NCT01813461
An Open-Label, Single-Dose Study to Determine the Metabolism and Elimination of 14C-Perampanel in Healthy Male Subjects
Eisai
NCT02116907
Pharmacokinetics and Bioavailability of Single Subcutaneous Doses of Methylnaltrexone Versus Intravenous Dose
Bausch Health Americas
NCT01367496
(+)-Alpha-Dihydrotetrabenazine Phase I
Kirk A. Frey
NCT02844179
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 47 |
| Phase 2 | 3 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Healthy Subjects Trial Landscape
ClinicalTrials.gov lists 70 US studies indexed under Healthy Subjects, and 14 of those are currently open to recruitment — roughly 20% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Healthy Subjects shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 50 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Healthy Subjects is led by GlaxoSmithKline with 7 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 70 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Healthy Subjects?
PlainTrial tracks 70 US clinical trials for Healthy Subjects, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Healthy Subjects?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.