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Gout
Open-data reference.
35 US clinical trials · 8 currently recruiting
Active & Recent Trials
Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout
Massachusetts General Hospital
NCT04875702
A Study of Dotinurad Versus Allopurinol in Participants With Gout
Crystalys Therapeutics
NCT07089875
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
Olatec Therapeutics
NCT05658575
Dose Response of Exercise for Arthritis Management
University of South Carolina
NCT06880653
Improving Gout Care After an ED Visit
University of Alabama at Birmingham
NCT06534554
A Study to Investigate the Clinical Effect and the Safety of PRX-115 Infused Intravenously at Different Dosing Regimens, With and Without Methotrexate, Versus Placebo in Adults Gout Patients (RELEASE)
Protalix
NCT07280156
Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares
Massachusetts General Hospital
NCT07346079
Evaluation of Efficacy and Safety of AR882 and XOI Co-administration in Uricase Treatment Failed Patients
Arthrosi Therapeutics
NCT07116746
Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-301)
Arthrosi Therapeutics
NCT06846515
Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients (AR882-302)
Arthrosi Therapeutics
NCT06439602
A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout
Amgen
NCT06229145
Gout in the ED and Improving Research Participation
University of Alabama at Birmingham
NCT04075903
Dose Finding Study to Evaluate Safety and Efficacy of 3 Dosages of SAP 001.
Shanton Pharma Pte.
NCT05690204
Phase II Study to Evaluate Efficacy and Safety of D-0120 in Combination With Allopurinol in Subjects With Gout
InventisBio Co.
NCT05665699
PK and Safety Evaluation Study of SAP-001 in Adult Subjects With Normal and Impaired Renal Function
Shanton Pharma Pte.
NCT06729853
Assessing the Role of the NLRP3 Inflammasome in Intercritical Gout
Attune Health Research
NCT04125459
Data Analysis for Drug Repurposing for Effective Alzheimer's Medicines - (DREAM) Probenecid vs Allopurinol
Brigham and Women's Hospital
NCT04746989
Virtual Gout Clinic
University of Alabama at Birmingham
NCT02790463
Combining Lesinurad With Allopurinol in Inadequate Responders
Ardea Biosciences
NCT01493531
Safety and Efficacy Study of PEG-uricase in the Treatment of Hyperuricemic Patients With Symptomatic Gout
Savient Pharmaceuticals
NCT00325195
Open-Label Extension Study for Patients Who Completed a Phase 3 Double-blind Study of PEG-uricase for Symptomatic Gout
Savient Pharmaceuticals
NCT01356498
Study to Evaluate the Urate-Lowering Activity and Safety of Oral BCX4208 Administered in Subjects With Gout
BioCryst Pharmaceuticals
NCT00985127
Safety and Pharmacodynamics of SEL-212 (Pegsiticase + SEL-110) in Subjects With Elevated Blood Uric Acid Levels
Selecta Biosciences
NCT02648269
Novel Methods for Ascertainment of Gout Flares -A Pilot Study
University of Alabama at Birmingham
NCT02855437
The Diet Gout Trial
Johns Hopkins University
NCT03569020
Mild, Moderate and Severe Renal Impairment Study
Ardea Biosciences
NCT02219516
The Effect of Colchicine on the Pharmacokinetic Profile of LC350189 in Healthy Aldults.
LG Chem
NCT03927677
NSAID Drug Interaction Study
Ardea Biosciences
NCT01884272
The Effect of Naproxen on the Pharmacokinetic Profile of LC350189 in Healthy Adults
LG Chem
NCT04139824
Safety and Pharmacodynamics of SEL-037 (Pegsiticase) in Subjects With Elevated Blood Uric Acid Levels
Selecta Biosciences
NCT02464605
Open Label PK, PD and DDI of Dotinurad and Allopurinol in Gout Patients with Hyperuricemia
Urica Therapeutics
NCT06056570
A Randomized, Double-Blind, Dose-Response Study of the Safety and Uric Acid Effects of Oral Ulodesine Added to Allopurinol in Subjects With Gout and Concomitant Moderate Renal Insufficiency
BioCryst Pharmaceuticals
NCT01407874
Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout
Amgen
NCT03635957
Pharmacokinetics and Pharmacodynamics of Anthocyanins
Rutgers, The State University of New Jersey
NCT03650140
UR+AIMS Gout Wearable Skin Uric Acid Monitor Study
University of California, Los Angeles
NCT06187519
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 8 |
| Phase 2 | 7 |
| Phase 3 | 6 |
| Phase 4 | 4 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Gout Trial Landscape
ClinicalTrials.gov lists 35 US studies indexed under Gout, and 8 of those are currently open to recruitment — roughly 23% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Gout shows 10 late-stage studies (Phase 3 and Phase 4 combined) alongside 15 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Gout is led by University of Alabama at Birmingham with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 35 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Gout?
PlainTrial tracks 35 US clinical trials for Gout, of which 8 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Gout?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.