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NCT03900026 · ClinicalTrials.gov registry record · Phase 4

Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery

A Phase 4 study of Atherosclerosis and Vein Occlusion, sponsored by Unity Health Toronto.

Completed
Registry status
Phase 4
Development phase
782
Enrollment target
20
Study locations

NCT03900026 is a Phase 4 study of Atherosclerosis and Vein Occlusion that has completed, run by Unity Health Toronto. The registered enrollment target is 782 participants, below the 1,054-participant average among 69 other Atherosclerosis trials with a reported enrollment target (26% lower). The trial reports 20 study locations across 10 states.

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The verdict

NCT03900026, a Phase 4 study of Atherosclerosis and Vein Occlusion, has completed, sponsored by Unity Health Toronto.

COMPLETED
Registry status
Phase 4
Development phase
782 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to determine if evolocumab added to regular statin therapy improves vein graft patency after coronary artery bypass graft (CABG) surgery.

Interventions

  • OTHER Placebo
  • DRUG Evolocumab

Study Locations (20)

Other

  • Royal Adelaide Hospital - Adelaide
  • Flinders Medical Centre - Bedford Park
  • Monash University - Melbourne
  • Fiona Stanley Hospital - Murdoch
  • Foothills Medical Centre - Calgary
  • Medical Centre Hungarian Defence Forces - Budapest

Ontario

  • Hamilton Health Sciences - Hamilton
  • Kingston Health Sciences Centre - Kingston
  • One Heart Care - Mississauga
  • North York Diagnostic and Cardiology Centre - North York
  • Sunnybrook Health Sciences Center - North York
  • St. Michael's Hospital - Toronto

California

  • San Francisco VA Medical Center - San Francisco

Florida

  • Jacksonville Center for Clinical Research - Jacksonville

Maine

  • Maine Medical Center - Portland

Minnesota

  • Minneapolis Heart Institute Foundation - Minneapolis

Ohio

  • University Hospital Cleveland Medical Center - Cleveland

Alberta

  • University of Alberta - Edmonton

Trial Details

FieldValue
Enrollment Target 782 participants
Start Date 2019-05-30
Est. Completion 2025-01-30
Phase Phase 4

Sponsor

Unity Health Toronto

12 total trials

What the Registry Record Tells You About NCT03900026

The ClinicalTrials.gov registry entry for NCT03900026 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 782 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,054-participant average among 69 other Atherosclerosis trials with a reported enrollment target (26% lower). The listed sponsor is Unity Health Toronto, which has 12 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Atherosclerosis appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT03900026 reports 20 study locations spanning 10 distinct geographic areas - top geographies include Other, Ontario, California.

Frequently Asked Questions

What is clinical trial NCT03900026 about?

NCT03900026 is a clinical study titled "Effect of Evolocumab on Saphenous Vein Graft Patency Following Coronary Artery Bypass Surgery". The purpose of this study is to determine if evolocumab added to regular statin therapy improves vein graft patency after coronary artery bypass graft (CABG) surgery.

What is the current status of trial NCT03900026?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 782 participants. The study started on 2019-05-30. Estimated completion is 2025-01-30.

What conditions does trial NCT03900026 study?

This clinical trial studies the following conditions: Atherosclerosis, Vein Occlusion, Coronary Artery Bypass Graft Surgery.

What interventions are being tested in trial NCT03900026?

The interventions under investigation include: Placebo (OTHER), Evolocumab (DRUG).

Who is sponsoring clinical trial NCT03900026?

This trial is sponsored by Unity Health Toronto, which has 12 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03900026 being conducted?

This trial has 20 study locations across California, Florida, Maine, Minnesota, Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.