Brigham and Women's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).

937 total trials 145 currently recruiting 608 completed early-phase tilt top decile by trial count

Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.

Top-decile sponsor footprint

Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 64/100

608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

937 total, page 1 of 19

RECRUITING Phase 2

Colchicine to Reduce Your SympToms And Lower Levels of Inflammation, Zeroing in on Effective CPPD Disease Treatment

NCT06855433

RECRUITING Phase 2

Uterine Transplant in Absolute Uterine Infertility (AUIF)

NCT02741102

RECRUITING NA

STABLE Pilates for Hypermobility

NCT07464093

RECRUITING NA

Deceased Uterine Transplant in Absolute Uterine Infertility (AUIF)

NCT04026893

RECRUITING Phase 4

Statins to Prevent Cancer Associated Blood Clots

NCT07303816

RECRUITING Phase 2

Nicotinamide Mononucleotide in Patients Undergoing CABG Surgery

NCT07013591

RECRUITING Phase 4

Dapagliflozin in Active Lupus Nephritis

NCT07323524

RECRUITING Phase 3

[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy

NCT07560306

RECRUITING NA

IntelliWell: An AI-Assisted Imaging Platform for Detection and Location of Ultra-Rare Testicular Sperm in Surgical Specimens

NCT07074015

RECRUITING NA

Post-Surgery Wound Healing Tracking With MyHealthPal App

NCT07391735

RECRUITING Phase 3

Robotic Opioid-free Prostatectomy Enhanced Strategy (ROPES)

NCT07427043

RECRUITING Phase 4

Comparing Digital Therapy, Trazodone, and Daridorexant for Menopause-Related Insomnia Symptoms

NCT07136415

RECRUITING Phase 1

Mindfulness Meditation for Insomnia

NCT06972303

RECRUITING NA

Yoga for Persistent Post-Surgical Pain (PPSP)

NCT06949007

RECRUITING NA

OsteoPorotic fracTure preventION System (OPTIONS) Research Study

NCT06731608

RECRUITING NA

Acute Psychiatric Care at Home for Lower-risk Patients With Acute Psychiatric Illness Who Require Inpatient Care

NCT07364825

RECRUITING NA

Efficacy of Routine Saline Flushing in the Prevention of Nephrostomy Tube Obstructions: A Pilot Study

NCT06987877

RECRUITING NA

Targeted Accelerated TMS for Post-Traumatic Stress Disorder

NCT07245641

RECRUITING Phase 2

Targeted Naltrexone to Support Individuals Participating in Dry January

NCT07132177

RECRUITING NA

Self-regulation of Real-time fMRI Brain Activity in Chronic Pain

NCT07023523

RECRUITING Phase 2

Extended-release Buprenorphine as a Novel Low-dose Induction Strategy

NCT06441604

RECRUITING Phase 4

Open Label Treprostinil Raynaud's Study

NCT07112183

RECRUITING Phase 2

Losartan to Improve Outcomes After Multi-ligament Knee Injury

NCT06933706

RECRUITING Phase 2

Study of Novel Therapeutics for Acute Remedy of Colitis

NCT06420492

RECRUITING Phase 2

Assessment of Foralumab Safety and Modulation of Microglial Activation in Alzheimer's Disease

NCT06489548

RECRUITING Phase 2

Study of Tirzepatide for Recovery and Alcohol Use Management

NCT06727331

RECRUITING NA

Assessment of the Feasibility of Using a Preoperative Surgical Fracture Analysis Tool

NCT07193524

RECRUITING NA

Using Reinforcement Learning to Personalize Electronic Health Record Tools to Facilitate Deprescribing

NCT06660979

RECRUITING NA

Accelerated TMS for Perinatal Depression

NCT06968390

RECRUITING

Quality of Life in Patients With Postoperative Atrial Fibrillation After Cardiac Surgery

NCT07173998

RECRUITING

Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in Neonates

NCT07275021

RECRUITING NA

Group Medical Visits and Chiropractic Care for Older Adults With Chronic Spine Pain

NCT06632535

RECRUITING NA

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

NCT06854458

RECRUITING NA

Cocoa Extract for Migraine Trial

NCT06808230

RECRUITING Phase 1

Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepository

NCT06789601

RECRUITING Phase 2

Semaglutide for Helping Opioid Recovery

NCT06639464

RECRUITING Phase 2

Intravenous Oxytocin for Post Operative Pain After Minimally Invasive Hysterectomy

NCT06483659

RECRUITING Phase 4

Glucose Consumption in MS Using [F-18]FDG-PET

NCT07087106

RECRUITING Phase 1

Short Course Radiation Treatment for Patients With Primary or Locally Recurrent Retroperitoneal Sarcoma Prior to Surgery

NCT06812052

RECRUITING NA

Assessment of Circuit Rebreathing During CPAP Therapy

NCT07062770

RECRUITING Phase 2

Treatment of UC With Novel Therapeutics

NCT06420375

RECRUITING NA

Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy

NCT06987890

RECRUITING NA

The Impact of Music Medicine on Preterm Brain Development and Behavior

NCT06536296

RECRUITING Early Phase 1

Assessment of Synaptic Density in MS

NCT04634994

RECRUITING NA

Acceptance and Commitment Therapy to Improve Disability in Chronic Migraine

NCT06795867

RECRUITING Phase 2

Enhanced Local Intensified Radiation Therapy in Elderly Glioblastoma: A Phase 2 Hybrid Randomized Trial

NCT06835803

RECRUITING NA

Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia

NCT06743659

RECRUITING NA

Chiropractic Care for Episodic Migraine

NCT06229834

RECRUITING NA

Refinement and Testing of Recruitment Methodology for Behavioral Medication Adherence Interventions Using Behavioral Science-based Approaches

NCT06569290

RECRUITING Phase 2

The Anabolic Effect of Testosterone on Pelvic Floor Muscles

NCT06111209

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What is open in the Brigham and Women's Hospital pipeline

145 recruiting of 937 indexed (15% open); 608 completed (65%).

Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).

Top condition: Type 2 Diabetes (13 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Brigham and Women's Hospital: open-pipeline peers nationwide

Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 5%10%15%20% Total trials Recruiting share Brigham and Women's HospitalColumbia UniversityHoffmann-La RocheUniversity of MinnesotaUniversity of California, Los AngelesIncyte CorporationNorthwestern UniversityNationwide Children's HospitalUniversity of Michigan Rogel Cancer Center
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 937 trials (± recruiting share)

Sponsors near 15% open enrollment (± trial volume)

What to do with this Brigham and Women's Hospital page

937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.

  • 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.