Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Anesthesia clinical trials
25 of 58 indexed Anesthesia trials are currently recruiting.
58 US clinical trials · 25 currently recruiting
Anesthesia is the subject of 58 registered US clinical trials on ClinicalTrials.gov, 25 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Massachusetts General Hospital, running 4 of these trials.
The research picture
Anesthesia has 58 registered US clinical trials, 25 of them open to new participants right now, about 43% of the total.
- 25
- recruiting participants now
- 43%
- of trials open to enrollment
- 16
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Massachusetts General Hospital
Active & Recent Trials
58 total, page 1 of 2
The Pediatric Anesthesia Quality Improvement Project
The Society for Pediatric Anesthesia
NCT00674388
The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes
Massachusetts General Hospital
NCT07022951
The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery
University of California, San Francisco
NCT06802224
Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
Washington University School of Medicine
NCT05991453
Anesthetics and Analgesics in Children
Chi Dang Hornik
NCT03427736
Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study
Oregon Health and Science University
NCT06036095
A Study of Changes in Heart Function and Blood Flow in People Receiving Anesthesia
Memorial Sloan Kettering Cancer Center
NCT05954832
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)
University of Texas Southwestern Medical Center
NCT05358535
Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
The University of Texas Health Science Center, Houston
NCT06029049
Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration
Massachusetts General Hospital
NCT07269808
Oral Methadone in Cardiac Surgery
Mayo Clinic
NCT07221617
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
Hospital for Special Surgery, New York
NCT03747146
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
University of California, San Diego
NCT04849455
Remimazolam NeuroImaging
Keith M Vogt
NCT07290205
Pilot Feasibility Trial of the SafeLM Supraglottic Airway (SGA)
The University of Texas Health Science Center, Houston
NCT05989880
Nitrous Oxide Neuroimaging
Keith M Vogt
NCT06702631
Ketamine and Propofol NeuroImaging
Keith M Vogt
NCT07294092
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
Boston Children's Hospital
NCT06326983
Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties
Melinda Seering
NCT05868330
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
Boston Children's Hospital
NCT03431064
Prospective IR-led Sedation Feasibility
CAMC Health System
NCT07443254
Poke and a Placebo
University of Minnesota
NCT04497220
Individual Cerebral Hemodynamic Oxygenation Relationships
Matthew Borzage
NCT04435834
Characterization of the Pudendal Nerve with Transvaginal Ultrasonography
University of Virginia
NCT06021782
REcovery From DEXmedetomidine-induced Unconsciousness
Massachusetts General Hospital
NCT06003127
A Study to Compare the Long-term Outcomes After Two Different Anaesthetics
Murdoch Childrens Research Institute
NCT03089905
AVATAR Anesthesia Alternative in Pediatric Radiotherapy: A Multi-Center Study
Stanford University
NCT03991156
Continuous Glucose Monitoring: A Pilot Study
Loma Linda University
NCT06614127
Detecting Post-surgical Respiratory Compromise and Prompting Patients to Self-rescue: An Early Feasibility Study
University of Utah
NCT02962557
Cataract Monitored Anesthesia Care (MAC) Feasibility Pilot Study
University of California, San Francisco
NCT06506669
Correlate of Surface Electroencephalogram (EEG) With Implanted EEG Recordings (ECOG)
Stanford University
NCT03629743
Assessment of Diagnostic Adequacy of AI-assisted Point-of-Care Echocardiography Among Anesthesiology Trainees
Loma Linda University
NCT06548373
Ultrasound-image Guided Versus Doppler Guided Versus Palpation Technique for Arterial Cannulation in Adults
University of Iowa
NCT01276171
Perioperative Audio for Anaesthesia
Brain.fm
NCT05291832
Evaluation of Bispectral Index (BIS™) and Levels of Sedation With Common Inhalational Anesthetics in Healthy Volunteers (OLIVER)
Medtronic - MITG
NCT04602546
Comparison of Ambu Auragain and I-Gel Supraglottic Airways in Adult Patients at an Ambulatory Surgery Center
University of Minnesota
NCT04286581
Comparison of Depth of Sedation Performance Between SedLine and Comparator Device During General Anesthesia
Masimo Corporation
NCT03865316
Comparison of Procedural Sedation in TEE
University of Alabama at Birmingham
NCT06129188
Papaverine vs Heparin for Peripheral Arterial Catheter Patency in Pediatric Patients
The University of Texas Health Science Center, Houston
NCT03894904
Sugammadex Versus Neostigmine for Reversal of Rocuronium Neuromuscular
The Cleveland Clinic
NCT03322657
Brain Networks and Consciousness
University of Texas Southwestern Medical Center
NCT04502550
Measurement of Hemodynamic Variables Under Spinal Anesthesia With Varied Positioning
The University of Texas Medical Branch, Galveston
NCT02883075
Comparing Local Anesthetics for TAP Block During Abdominally-based Free Flap for Breast Reconstruction
Vanderbilt University Medical Center
NCT03700970
Methadone in Ambulatory Surgery
Washington University School of Medicine
NCT02300077
Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables
Nationwide Children's Hospital
NCT03054922
Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Milton S. Hershey Medical Center
NCT02624050
Dose-Ranging Study of Intranasal Kovacaine Mist in Pediatric Subjects
St. Renatus
NCT01701505
Educating Anesthesia Residents to Improve Perioperative Care for the Elderly
Duke University
NCT03008863
Acupuncture ACL (Anterior Cruciate Ligament)
Hospital for Special Surgery, New York
NCT03711734
Investigating Near-Threshold Perception During Anesthetic Sedation
University of Michigan
NCT06403852
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 5 |
| Phase 3 | 5 |
| Phase 4 | 11 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anesthesia Trial Landscape
58 indexed Anesthesia studies · 25 recruiting (43%).
Phase mix: 16 late (III/IV) vs 10 early (I/II).
Top sponsor: Massachusetts General Hospital (4 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anesthesia?
PlainTrial tracks 58 US clinical trials for Anesthesia, of which 25 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anesthesia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.