Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04435834 · ClinicalTrials.gov registry record · Phase 4
Individual Cerebral Hemodynamic Oxygenation Relationships
A Phase 4 study of Anesthesia and Anesthesia; Reaction, sponsored by Matthew Borzage.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT04435834: Recruiting Phase 4 study of Anesthesia and Anesthesia; Reaction, sponsored by Matthew Borzage.
NCT04435834 is a Phase 4 study of Anesthesia and Anesthesia; Reaction that is actively recruiting participants, run by Matthew Borzage. The registered enrollment target is 30 participants, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04435834, a Phase 4 study of Anesthesia and Anesthesia; Reaction, is actively recruiting participants, sponsored by Matthew Borzage.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized controlled trial in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: propofol or sevoflurane. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of propofol and sevoflurane are in clinical equipoise will be offered to have the anesthesia they will receive during their MRI randomized. All eligible subjects will be asked to provide informed consent before participating in the study.
Primary Outcome
Phase contrast (PC) acquisition via MRI will be used to assess any impact of anesthesia on cerebral blood flow.
Conditions Studied
Interventions
- DRUG Propofol or Sevoflurane
Study Locations (1)
California
- Children's Hospital Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2020-06-09 |
| Est. Completion | 2026-09-10 |
| Phase | Phase 4 |
What NCT04435834 shows while recruiting
NCT04435834 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower).
The record links to 2 conditions, with Anesthesia appearing as the primary indexed condition, and to 1 intervention - of which Propofol or Sevoflurane is the first listed.
NCT04435834 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT04435834 about?
NCT04435834 is a clinical study titled "Individual Cerebral Hemodynamic Oxygenation Relationships". This is a randomized controlled trial in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by two types of anesthesia: propofol or sevoflurane. Subjects who require clinic...
What is the current status of trial NCT04435834?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 30 participants. The study started on 2020-06-09. Estimated completion is 2026-09-10.
What conditions does trial NCT04435834 study?
This clinical trial studies the following conditions: Anesthesia, Anesthesia; Reaction.
What interventions are being tested in trial NCT04435834?
The interventions under investigation include: Propofol or Sevoflurane (DRUG).
Who is sponsoring clinical trial NCT04435834?
This trial is sponsored by Matthew Borzage, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04435834 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anesthesia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04435834's enrollment target sits among peer trials
30 45th of 57 higher than 11 of 57 other Anesthesia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anesthesia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study
RECRUITING · Phase 4
-
Oral Methadone in Cardiac Surgery
RECRUITING · Phase 4
-
Comparison of Intubation Conditions During Rapid Sequence Induction Obtained With Modified Time Principal Induction With a Standard Intubation Dose of Rocuronium Versus Succinylcholine
RECRUITING · Phase 4
-
The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery
RECRUITING · Phase 4
-
Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties
RECRUITING · Phase 4
-
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
RECRUITING · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00977977 · 30 participants · Phase 2
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy
- NCT01459107 · 30 participants · Phase 2
Human Upper Extremity Allotransplantation
- NCT01666080 · 30 participants · NA
Second or Greater Allogeneic Hematopoietic Stem Cell Transplant Using Reduced Intensity Conditioning (RIC)
- NCT01720836 · 30 participants · Phase 1
Study of the Immune Response of MUC1 (Mucin1) Peptide Vaccine for Non-small Cell Lung Cancer
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI