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NCT07294092 · ClinicalTrials.gov registry record · Early Phase 1
Ketamine and Propofol NeuroImaging
A Early Phase 1 study of Pain and Anesthesia, sponsored by Keith M Vogt.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT07294092: Recruiting Early Phase 1 study of Pain and Anesthesia, sponsored by Keith M Vogt.
NCT07294092 is a Early Phase 1 study of Pain and Anesthesia that is actively recruiting participants, run by Keith M Vogt. The registered enrollment target is 60 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (80% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07294092, a Early Phase 1 study of Pain and Anesthesia, is actively recruiting participants, sponsored by Keith M Vogt.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a multi-visit which will collect MRI (pictures of the brain) and EEG (brain waves) data to determine changes in brain connectivity and brain activity for memory formation and pain perception while receiving the commonly-used anesthetic agents ketamine and propofol, both alone and in combination.
Primary Outcome
Recognition memory testing, using the Remember-Know procedure, in which subjects indicate whether they recognize previously experienced experimental items among novel items (not previously in the experiment). This allows calculation of interdependent measures of recollection \& familiarity using the signal detection statistic, d'. d' is calculated as the cumulative Gaussian distribution of false positive responses subtracted from the cumulative Gaussian distribution of correctly identified previ
Conditions Studied
Interventions
- DRUG Ketamine
- DRUG Propofol
- DEVICE Peripheral Nerve Stimulation
Study Locations (1)
Pennsylvania
- University of Pittsburgh - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-03-01 |
| Est. Completion | 2028-08-02 |
| Phase | Early Phase 1 |
What NCT07294092 shows while recruiting
NCT07294092 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (80% lower).
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 3 interventions - of which Ketamine is the first listed.
NCT07294092 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07294092 about?
NCT07294092 is a clinical study titled "Ketamine and Propofol NeuroImaging". This is a multi-visit which will collect MRI (pictures of the brain) and EEG (brain waves) data to determine changes in brain connectivity and brain activity for memory formation and pain perception while receiving the commonly-used anesthetic agents ketamine and propofol, both alone and in combinat...
What is the current status of trial NCT07294092?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 60 participants. The study started on 2026-03-01. Estimated completion is 2028-08-02.
What conditions does trial NCT07294092 study?
This clinical trial studies the following conditions: Pain, Anesthesia.
What interventions are being tested in trial NCT07294092?
The interventions under investigation include: Ketamine (DRUG), Propofol (DRUG), Peripheral Nerve Stimulation (DEVICE).
Who is sponsoring clinical trial NCT07294092?
This trial is sponsored by Keith M Vogt, which has 7 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07294092 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Pain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07294092's enrollment target sits among peer trials
60 224th of 374 higher than 134 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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