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NCT06003127 · ClinicalTrials.gov registry record · NA
REcovery From DEXmedetomidine-induced Unconsciousness
A NA study of Healthy and Anesthesia, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- NA
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT06003127: Recruiting NA study of Healthy and Anesthesia, sponsored by Massachusetts General Hospital.
NCT06003127 is a NA study of Healthy and Anesthesia that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 12 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06003127, a NA study of Healthy and Anesthesia, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- NA
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
This pilot study in healthy volunteers aims to determine if biological sex has an impact on recovery from dexmedetomidine-induced unconsciousness, and if transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) can be used to measure brain complexity during dexmedetomidine sedation without arousing study participants.
Primary Outcome
The time to return of responsiveness will be measured in minutes and from the moment of dexmedetomidine discontinuation to the return of clicking a button in response to auditory stimulation.
Conditions Studied
Interventions
- DEVICE Transcranial Magnetic Stimulation-Electroencephalography
Study Locations (1)
Massachusetts
- Massachusetts General Hospital - Boston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2024-11-15 |
| Est. Completion | 2026-12 |
| Phase | NA |
What NCT06003127 shows while recruiting
NCT06003127 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower).
The record links to 3 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Magnetic Stimulation-Electroencephalography is the first listed.
NCT06003127 reports a single indexed study location in Massachusetts.
Frequently Asked Questions
What is clinical trial NCT06003127 about?
NCT06003127 is a clinical study titled "REcovery From DEXmedetomidine-induced Unconsciousness". This pilot study in healthy volunteers aims to determine if biological sex has an impact on recovery from dexmedetomidine-induced unconsciousness, and if transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) can be used to measure brain complexity during dexmedetomidine se...
What is the current status of trial NCT06003127?
This trial is currently recruiting. It is a NA study. The enrollment target is 12 participants. The study started on 2024-11-15. Estimated completion is 2026-12.
What conditions does trial NCT06003127 study?
This clinical trial studies the following conditions: Healthy, Anesthesia, Consciousness, Level Altered.
What interventions are being tested in trial NCT06003127?
The interventions under investigation include: Transcranial Magnetic Stimulation-Electroencephalography (DEVICE).
Who is sponsoring clinical trial NCT06003127?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06003127 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06003127's enrollment target sits among peer trials
12 996th of 1090 higher than 61 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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