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NCT06036095 · ClinicalTrials.gov registry record · Phase 4

Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study

A Phase 4 study of Anesthesia and Neurocognitive Disorders, sponsored by Oregon Health and Science University.

Recruiting
Registry status
Phase 4
Development phase
260
Enrollment target
1
Study location

NCT06036095 is a Phase 4 study of Anesthesia and Neurocognitive Disorders that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 260 participants, below the 109,406-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06036095, a Phase 4 study of Anesthesia and Neurocognitive Disorders, is actively recruiting participants, sponsored by Oregon Health and Science University.

RECRUITING
Registry status
Phase 4
Development phase
260 participants
Enrollment target
1
Study location

Study Summary

Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (IV) can prevent deleterious postoperative outcomes in the geriatric surgical population. The goal of this clinical trial is to determine whether intravenous anesthesia (IV) leads to a decreased incidence of postoperative delirium (POD), postoperative cognitive dysfunction (POCD), and functional decline, and improved patient-reported outcomes (PROs) in older adults undergoing non-cardiac surgery when compared to the standard inhalational anesthesia (GAS). This single-center, 1:1 randomized, double-blind (patient \& outcome assessor) clinical trial will compare inhalational vs. intravenous anesthesia on POD, POCD, functional status, patient-reported outcomes (PROs), and blood-based biomarkers in older patients undergoing elective, inpatient, non-cardiac surgery. Upon enrollment, 260 women and men ≥ 70 years undergoing elective noncardiac surgery under general anesthesia will be randomized to 2 groups: TIVA or GAS.

Conditions Studied

Anesthesia Neurocognitive Disorders Post-operative Delirium Post-operative Cognitive Dysfunction

Interventions

  • DRUG Sevoflurane
  • DRUG Propofol

Study Locations (1)

Oregon

  • Oregon Health & Science University - Portland

Trial Details

FieldValue
Enrollment Target 260 participants
Start Date 2023-08-14
Est. Completion 2027-03-15
Phase Phase 4

Sponsor

Oregon Health and Science University

546 total trials

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What the Registry Record Tells You About NCT06036095

The ClinicalTrials.gov registry entry for NCT06036095 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 260 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 109,406-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The listed sponsor is Oregon Health and Science University, which has 546 total studies on file at ClinicalTrials.gov.

The record links to 4 conditions, with Anesthesia appearing as the primary indexed condition, and to 2 interventions - of which Sevoflurane is the first listed.

NCT06036095 reports 1 study location spanning 1 distinct geographic area - top geographies include Oregon.

Frequently Asked Questions

What is clinical trial NCT06036095 about?

NCT06036095 is a clinical study titled "Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study". Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (IV) can prevent deleterious postoperative outcomes in the geriatric surgical population. The goal of this clinical trial is to determine wheth...

What is the current status of trial NCT06036095?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 260 participants. The study started on 2023-08-14. Estimated completion is 2027-03-15.

What conditions does trial NCT06036095 study?

This clinical trial studies the following conditions: Anesthesia, Neurocognitive Disorders, Post-operative Delirium, Post-operative Cognitive Dysfunction.

What interventions are being tested in trial NCT06036095?

The interventions under investigation include: Sevoflurane (DRUG), Propofol (DRUG).

Who is sponsoring clinical trial NCT06036095?

This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06036095 being conducted?

This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.