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NCT06036095 · ClinicalTrials.gov registry record · Phase 4
Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study
A Phase 4 study of Anesthesia and Postoperative Delirium, sponsored by Oregon Health and Science University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 260
- Enrollment target
- 1
- Study location
NCT06036095: Recruiting Phase 4 study of Anesthesia and Postoperative Delirium, sponsored by Oregon Health and Science University.
NCT06036095 is a Phase 4 study of Anesthesia and Postoperative Delirium that is actively recruiting participants, run by Oregon Health and Science University. The registered enrollment target is 260 participants, below the 109,406-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06036095, a Phase 4 study of Anesthesia and Postoperative Delirium, is actively recruiting participants, sponsored by Oregon Health and Science University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 260 participants
- Enrollment target
- 1
- Study location
Study Summary
Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (IV) can prevent deleterious postoperative outcomes in the geriatric surgical population. The goal of this clinical trial is to determine whether intravenous anesthesia (IV) leads to a decreased incidence of postoperative delirium (POD), postoperative cognitive dysfunction (POCD), and functional decline, and improved patient-reported outcomes (PROs) in older adults undergoing non-cardiac surgery when compared to the standard inhalational anesthesia (GAS). This single-center, 1:1 randomized, double-blind (patient \& outcome assessor) clinical trial will compare inhalational vs. intravenous anesthesia on POD, POCD, functional status, patient-reported outcomes (PROs), and blood-based biomarkers in older patients undergoing elective, inpatient, non-cardiac surgery. Upon enrollment, 260 women and men ≥ 70 years undergoing elective noncardiac surgery under general anesthesia will be randomized to 2 groups: TIVA or GAS.
Primary Outcome
Incidence of postoperative delirium with the 3D-Confusion Assessment Method (3D-CAM) in non-intubated patients and the CAM-ICU-7 in intubated patients. Delirium will be assessed postoperative in PACU and twice daily on postoperative days 1-3 while the patient is in the hospital.
Conditions Studied
Interventions
- DRUG Sevoflurane
- DRUG Propofol
Study Locations (1)
Oregon
- Oregon Health & Science University - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 260 participants |
| Start Date | 2023-08-14 |
| Est. Completion | 2027-03-15 |
| Phase | Phase 4 |
What NCT06036095 shows while recruiting
NCT06036095 is an interventional study that assigns participants to a tested intervention. The registered 260 participants enrollment target is mid-sized for trials with a published cap, below the 109,406-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower).
The record links to 4 conditions, with Anesthesia appearing as the primary indexed condition, and to 2 interventions - of which Sevoflurane is the first listed.
NCT06036095 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT06036095 about?
NCT06036095 is a clinical study titled "Total Intravenous Versus Inhalational Anesthesia- A Geriatric Anesthesia Study". Traditionally, general anesthesia is maintained with inhalational anesthesia (GAS), but there is a gap in knowledge regarding whether intravenous anesthesia (IV) can prevent deleterious postoperative outcomes in the geriatric surgical population. The goal of this clinical trial is to determine wheth...
What is the current status of trial NCT06036095?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 260 participants. The study started on 2023-08-14. Estimated completion is 2027-03-15.
What conditions does trial NCT06036095 study?
This clinical trial studies the following conditions: Anesthesia, Postoperative Delirium, Neurocognitive Disorders, Postoperative Cognitive Dysfunction.
What interventions are being tested in trial NCT06036095?
The interventions under investigation include: Sevoflurane (DRUG), Propofol (DRUG).
Who is sponsoring clinical trial NCT06036095?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06036095 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anesthesia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06036095's enrollment target sits among peer trials
260 9th of 57 higher than 49 of 57 other Anesthesia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anesthesia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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