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NCT07022951 · ClinicalTrials.gov registry record

The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes

A clinical trial of Surgery and Anesthesia, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
1,200,000
Enrollment target
1
Study location

NCT07022951: Recruiting study of Surgery and Anesthesia, sponsored by Massachusetts General Hospital.

NCT07022951 is a study of Surgery and Anesthesia that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 1,200,000 participants, above the 42,852-participant average among 120 other Surgery trials with a reported enrollment target (2700% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07022951, a study of Surgery and Anesthesia, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
1,200,000 participants
Enrollment target
1
Study location

Study Summary

Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful. This study intends to characterize perioperative fasting practices and their potential effects on clinical outcomes through possible effects on patient well-being (anxiety, hunger, thirst), physiology (hypovolemia, hypotension), perioperative aspiration, etc. We hypothesized that in addition to known adverse effects on patients' well-being, prolonged preoperative fasting adversely affects circulating blood volume-related (hypotension, decreased urine output etc.) and glucose metabolism-related (e.g., hypo/hyperglycemia) perioperative physiology. Additional knowledge on the potential adverse effects of preoperative fasting will inform preoperative fasting policies and research interventions that are relevant to hundreds of millions of patients subjected to preoperative/preprocedural fasting worldwide each year.

Interventions

  • OTHER Preoperative fasting

Study Locations (1)

Massachusetts

  • Mass General Brigham - Boston

Trial Details

FieldValue
Enrollment Target 1,200,000 participants
Start Date 2016-01-01
Est. Completion 2030-12-31

Sponsor

Massachusetts General Hospital

2,032 total trials

What the Registry Record Tells You About NCT07022951

The ClinicalTrials.gov registry entry for NCT07022951 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 1,200,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 42,852-participant average among 120 other Surgery trials with a reported enrollment target (2700% higher). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.

The record links to 9 conditions, with Surgery appearing as the primary indexed condition, and to 1 intervention - of which Preoperative fasting is the first listed.

NCT07022951 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07022951 about?

NCT07022951 is a clinical study titled "The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes". Perioperative fasting has historically been viewed as a low-risk intervention. However, preliminary data indicate that perioperative loss of nutrition and fluids is likely harmful. This study intends to characterize perioperative fasting practices and their potential effects on clinical outcomes thr...

What is the current status of trial NCT07022951?

This trial is currently recruiting. The enrollment target is 1,200,000 participants. The study started on 2016-01-01. Estimated completion is 2030-12-31.

What conditions does trial NCT07022951 study?

This clinical trial studies the following conditions: Surgery, Anesthesia, Sedation, Aspiration; Gastric Contents, Anesthesia, Monitored Anesthesia Care.

What interventions are being tested in trial NCT07022951?

The interventions under investigation include: Preoperative fasting (OTHER).

Who is sponsoring clinical trial NCT07022951?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07022951 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.