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NCT07443254 · ClinicalTrials.gov registry record · Phase 1
Prospective IR-led Sedation Feasibility
A Phase 1 study of Anesthesia and Sedation and Analgesia, sponsored by CAMC Health System.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07443254: Recruiting Phase 1 study of Anesthesia and Sedation and Analgesia, sponsored by CAMC Health System.
NCT07443254 is a Phase 1 study of Anesthesia and Sedation and Analgesia that is actively recruiting participants, run by CAMC Health System. The registered enrollment target is 40 participants, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07443254, a Phase 1 study of Anesthesia and Sedation and Analgesia, is actively recruiting participants, sponsored by CAMC Health System.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study wants to see if some interventional radiology (IR) procedures can be done without using general anesthesia. General anesthesia needs a lot of staff and equipment. It can also cause side effects. There are not enough anesthesia providers, which makes it harder to use for every procedure. The researchers will test deep sedation with ketamine instead. They will start with 20 patients. If it works well and is safe, they may include up to 40 patients. Patients will be asked to join the study before their procedure. The anesthesia team will be told ahead of time and will be ready to help if needed. The IR team will give the deep sedation and follow all safety rules. The main goal is to finish the procedure without stopping early or switching to general anesthesia. The study will call this successful if fewer than 10% of cases fail. The researchers will also look at patient pain, patient satisfaction, any side effects, and how long recovery takes.
Primary Outcome
For Aim 1, feasibility will be assessed by calculating the proportion of procedures completed without failure, where failure is defined as procedure abortion due to inadequate sedation or patient intolerance, or escalation to anesthesiology takeover and/or conversion to general anesthesia. The observed failure proportion will be reported with exact (Clopper-Pearson) 95% confidence intervals. Feasibility will be interpreted relative to the prespecified threshold of ≤10% failure.
Conditions Studied
Interventions
- DRUG Midazolam
- DRUG ketamine
- DRUG Fentanyl (IV)
Study Locations (1)
West Virginia
- CAMC Memorial - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-03-02 |
| Est. Completion | 2027-04-03 |
| Phase | Phase 1 |
What NCT07443254 shows while recruiting
NCT07443254 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Anesthesia appearing as the primary indexed condition, and to 3 interventions - of which Midazolam is the first listed.
NCT07443254 reports a single indexed study location in West Virginia.
Frequently Asked Questions
What is clinical trial NCT07443254 about?
NCT07443254 is a clinical study titled "Prospective IR-led Sedation Feasibility". This study wants to see if some interventional radiology (IR) procedures can be done without using general anesthesia. General anesthesia needs a lot of staff and equipment. It can also cause side effects. There are not enough anesthesia providers, which makes it harder to use for every procedure. ...
What is the current status of trial NCT07443254?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2026-03-02. Estimated completion is 2027-04-03.
What conditions does trial NCT07443254 study?
This clinical trial studies the following conditions: Anesthesia, Sedation and Analgesia, Interventional Radiology.
What interventions are being tested in trial NCT07443254?
The interventions under investigation include: Midazolam (DRUG), ketamine (DRUG), Fentanyl (IV) (DRUG).
Who is sponsoring clinical trial NCT07443254?
This trial is sponsored by CAMC Health System, which has 28 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07443254 being conducted?
This trial has 1 study location across West Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07443254's enrollment target sits among peer trials
40 38th of 57 higher than 16 of 57 other Anesthesia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anesthesia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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