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NCT02300077 · ClinicalTrials.gov registry record · NA

Methadone in Ambulatory Surgery

A NA study of Postoperative Pain and Anesthesia, sponsored by Washington University School of Medicine.

Completed
Registry status
NA
Development phase
60
Enrollment target
1
Study location

NCT02300077: Completed NA study of Postoperative Pain and Anesthesia, sponsored by Washington University School of Medicine.

NCT02300077 is a NA study of Postoperative Pain and Anesthesia that has completed, run by Washington University School of Medicine. The registered enrollment target is 60 participants, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (74% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02300077, a NA study of Postoperative Pain and Anesthesia, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
NA
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

The μ-opioid receptor agonist methadone is frequently used in adult anesthesia and adult pain therapy. Methadone has an extremely long half-life, which confers therapeutic advantage by providing more stable plasma concentrations and long-lasting pain relief. Methadone perioperative pharmacokinetics and effectiveness in perioperative pain relief in inpatients is well characterized. There is, however, no information on methadone use in an ambulatory surgery setting and outpatient procedures. This pilot investigation will determine effectiveness of intraoperative methadone in reducing postoperative opioid consumption and providing improved pain relief in patients undergoing moderately painful, ambulatory surgical procedures.

Primary Outcome

Data on opioids administered intraoperatively will be collected from the subject's EMR.

Interventions

  • DRUG methadone
  • DRUG Control (Intra-operative administration of opioids, other than methadone)

Study Locations (1)

Missouri

  • Barnes-Jewish Hospital - St Louis

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2014-12
Est. Completion 2018-02-12
Phase NA

What the finished NCT02300077 record still lists

NCT02300077 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 231-participant average among 120 other Postoperative Pain trials with a reported enrollment target (74% lower).

The record links to 2 conditions, with Postoperative Pain appearing as the primary indexed condition, and to 2 interventions - of which methadone is the first listed.

NCT02300077 reports a single indexed study location in Missouri.

Frequently Asked Questions

What is clinical trial NCT02300077 about?

NCT02300077 is a clinical study titled "Methadone in Ambulatory Surgery". The μ-opioid receptor agonist methadone is frequently used in adult anesthesia and adult pain therapy. Methadone has an extremely long half-life, which confers therapeutic advantage by providing more stable plasma concentrations and long-lasting pain relief. Methadone perioperative pharmacokinetics ...

What is the current status of trial NCT02300077?

This trial is currently completed. It is a NA study. The enrollment target is 60 participants. The study started on 2014-12. Estimated completion is 2018-02-12.

What conditions does trial NCT02300077 study?

This clinical trial studies the following conditions: Postoperative Pain, Anesthesia.

What interventions are being tested in trial NCT02300077?

The interventions under investigation include: methadone (DRUG), Control (Intra-operative administration of opioids, other than methadone) (DRUG).

Who is sponsoring clinical trial NCT02300077?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02300077 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Postoperative Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02300077's enrollment target sits among peer trials

60 97th of 120 higher than 22 of 120 other Postoperative Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Postoperative Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02300077, the US trial registry maintained by the National Library of Medicine. NCT02300077 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.