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ClinicalTrials.gov 24 recruiting now early-phase tilt

Exercise: early-phase trial registry

24 of 58 indexed Exercise trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #244 of 28,707 conditions by registered trial count.

58 US clinical trials · 24 currently recruiting · #244 of 28,707 conditions by registered trial count

Exercise: 58 US clinical trials tracked, 24 recruiting.

Exercise is the subject of 58 registered US clinical trials on ClinicalTrials.gov, 24 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Arizona State University, running 4 of these trials.

Enrollment posture brief

Registry condition exercise

OPEN 24 | RECR 41% | LATE 0 | EARLY 9 | RANK #244 | SPON 4

Nearest open-share peer: Dyslipidemias (41% recruiting · 29 trials)

Recurrent Acute Myeloid Leuk51.7%Anesthesia43.1%Exercise (this)41%Non-alcoholic Fatty Liver Di32.8%Diabetic Retinopathy25.9%
Open-enrollment share among volume-matched conditions near Exercise

Exercise lists 24 open slots (41% of 58 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Exercise on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Exercise recruits in line with its size-band peers.

    24 of 58 indexed trials (41.4%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Exercise trials is spread across many organizations.

    Arizona State University accounts for 4 of 58 trials (6.9%). 48 distinct sponsors appear on at least one study for this condition label.

  3. Most Exercise trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 58 trials that report a genuine target (sentinel values excluded). 36 of those (62.1%) plan for fewer than 100 participants.

  4. Exercise research is mostly interventional.

    53 interventional and 5 observational studies make up this index (91.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 25

Open and recent trials

58 total, page 1 of 2

RECRUITING 500,000 participants

Apple Health Study

Apple

NCT06958523

RECRUITING Phase 1 240 participants

Evaluation of the Walk With Ease Program for Fall Prevention

Iowa State University

NCT05693025

RECRUITING Phase 2 240 participants

Smart Walk: A Culturally Tailored Smartphone-Delivered Physical Activity Intervention for African American Women

Arizona State University

NCT06337708

RECRUITING Phase 2 200 participants

Response to Exercise and Nitric Oxide in PAD

Northwestern University

NCT06657976

RECRUITING NA 200 participants

Postnatal Exercise to Activate Baby's Brown Fat

Joslin Diabetes Center

NCT07467694

RECRUITING NA 200 participants

GENESIS: Genotype Guided - Natriuretic Peptides - Cardiometabolic Health Study

University of Alabama at Birmingham

NCT05216042

RECRUITING NA 150 participants

Better Lifestyle Counseling for African American Women During Pregnancy

University of Illinois at Chicago

NCT05234125

RECRUITING NA 144 participants

Goal Setting to Promote Physical Activity Adherence in Midlife Adults

Arizona State University

NCT05980052

RECRUITING 100 participants

Physical and Cognitive Aging Study in Older Adults

University of Florida

NCT06726616

RECRUITING NA 50 participants

The Role of Mobile Apps in Promoting Cardiovascular Health and Motivation to Exercise During Pregnancy

Old Dominion University

NCT07166822

RECRUITING NA 50 participants

Exploring the Relationship Between Heart Rate Variability (HRV), Training Load, and Exercise Performance

PepsiCo Global R&D

NCT06425939

RECRUITING Phase 2 50 participants

Vasodilator and Exercise Study for DMD (VASO-REx)

University of Florida

NCT06290713

RECRUITING Phase 2 40 participants

Fasted vs. Fed State Exercise

Arkansas Colleges of Health Education

NCT07487090

RECRUITING Early Phase 1 40 participants

Influence of Short-Term Antibiotic Therapy on Exercise

Rutgers, The State University of New Jersey

NCT05961189

RECRUITING NA 40 participants

How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types

George Washington University

NCT06691100

RECRUITING NA 40 participants

Exercise-induced Hypoalgesia and Proprioceptive Changes, Comparing Isometric to Isotonic Neck Exercises

University of South Dakota

NCT06465394

RECRUITING NA 40 participants

The Impact of Removal of Exercise on Glycemic Control and Vascular Health in Older Active Adults

Old Dominion University

NCT05468255

RECRUITING NA 36 participants

Time to Move in Pregnancy Hyperglycemia

The University of Tennessee, Knoxville

NCT06125704

RECRUITING NA 30 participants

The VESPA Pilot Study

Wake Forest University

NCT04756245

RECRUITING NA 20 participants

Developing a Nutritional Supplement to Increase Collagen Synthesis in People

University of California, Davis

NCT06138106

RECRUITING NA 20 participants

Feasibility, Safety and Acceptability of a Mobile Health Delivered Exercise Training Program in Patients With Nonalcoholic Steatohepatitis

Milton S. Hershey Medical Center

NCT06195943

RECRUITING NA 20 participants

Latinas Integrating Fitness and Therapy

Colorado State University

NCT07223346

RECRUITING NA 15 participants

Effect of Exercise and Heat Stress on Acute Cardiometabolic Adaptations in Healthy Young Adults

Northern Arizona University

NCT06872762

RECRUITING NA 14 participants

Ketone Monoester Supplements, High Altitude, and Brain Blood Flow During Exercise

McMaster University

NCT07063732

ACTIVE NOT RECRUITING NA 432 participants

Mentoring to be Active for Rural Appalachia Children

Ohio State University

NCT05758441

ACTIVE NOT RECRUITING NA 126 participants

Gut Microbe Composition, Exercise, and Breast Breast Cancer Survivors

University of Alabama at Birmingham

NCT04088708

ACTIVE NOT RECRUITING NA 58 participants

Hispanic Adapted and Culturally Relevant Exercising Together

University of Arizona

NCT06018311

COMPLETED Phase 1 1,422 participants

The Active by Choice Today (ACT) Trial to Increase Physical Activity

University of South Carolina

NCT01028144

COMPLETED NA 1,356 participants

Back to ECE Safely With SAGE: Reducing COVID-19 Transmission in Hispanic and Low-income Preschoolers

Arizona State University

NCT05178290

COMPLETED NA 422 participants

The Effect of Community Building Through Virtual, Team-Based Exercise on Burnout

Harvard Medical School (HMS and HSDM)

NCT05194410

COMPLETED NA 309 participants

Community-based Intervention Effects on Older Adults' Physical Activity

University of Minnesota

NCT03326141

COMPLETED NA 200 participants

Exercise & Diet Effects on CV Risk in Firefighters

University of New Hampshire

NCT03344198

COMPLETED 198 participants

The Comparison of Energy in Take and Body Weight EXERCISE

Pennington Biomedical Research Center

NCT01264406

COMPLETED NA 142 participants

Healthy Motivations for Moms-to-be Study

University of South Carolina

NCT03063528

COMPLETED NA 137 participants

Promoting Contextually Cued PA Habits

Arizona State University

NCT04691596

COMPLETED Phase 2 116 participants

Safety and Efficacy of Combining Intranasal Insulin & Acute Exercise

Michigan State University

NCT04292535

COMPLETED 113 participants

PEAKS: Validation of Mobile Technologies

University of Florida

NCT02888483

COMPLETED NA 110 participants

Combined Technology Enhanced Home Exercise Program and Other Non-pharmacological Intervention for Cancer Survivors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT03576274

COMPLETED NA 88 participants

Lung Transplant G0 (LTGO): Improving Self-Management of Exercise After Lung Transplantation

University of Pittsburgh

NCT03728257

COMPLETED NA 66 participants

Exercise in Pregnancy for Reduction of Blood Pressure in Obese Patients

Milton S. Hershey Medical Center

NCT01261884

COMPLETED NA 61 participants

Extending Contingency Management's Benefits With Progressively Increasing Variable Interval Prize Reinforcement

UConn Health

NCT01184040

COMPLETED NA 60 participants

Microalgae Extract Phaeosol Combined to Exercise in Healthy Overweight Women : Efficacy on Body Weight Management

Microphyt

NCT04761406

COMPLETED Phase 1 55 participants

The Role of Arnica on Muscle Pain Following Eccentric Exercise

The University of Texas Health Science Center, Houston

NCT00504010

COMPLETED NA 50 participants

A Comparison of Exercise Beliefs to Same-day Exercise Behavior

Brown University

NCT03415542

COMPLETED NA 49 participants

Dietary Supplements and Exercise in Aging Adults

Purdue University

NCT00761553

COMPLETED NA 41 participants

Effects of a Short-term Exercise Intervention on Sleep in Women Exposed to Trauma: A Randomized Controlled Trial

University of Georgia

NCT05097352

COMPLETED NA 40 participants

Exercise Values of Life and Vitality Everyday

The Miriam Hospital

NCT03565731

COMPLETED NA 36 participants

Physical Activity Smartphone App for African American Men (FitBros) Ph II

Klein Buendel

NCT05621044

COMPLETED NA 36 participants

INcreasing Steps in PREgnancy Study

University of Iowa

NCT05455008

COMPLETED NA 35 participants

Effect of Beta-Alanine on Heart Rate Response

University of North Carolina, Chapel Hill

NCT01745016

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Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 5

Named interventions

Most-linked intervention names on Exercise records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Dietary supplement
3 trials
Exercise Behavioral
2 trials
Remotely-delivered health coaching intervention Behavioral
1 trials
Second 3 months of virtual, team-based exercise Behavioral
1 trials
First 3 months of virtual, team-based exercise Behavioral
1 trials
App use instructions Behavioral
1 trials
Habit Coaching Behavioral
1 trials
Cue-contingent weekly incentives Behavioral
1 trials

US sites by state

Facility locations filed on Exercise trials. A trial with sites in several states counts in each.

Arizona 5 trials
Massachusetts 4 trials
Texas 3 trials
Pennsylvania 3 trials
North Carolina 3 trials
Illinois 3 trials
Florida 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Exercise page

58 registered trials, 24 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Exercise condition card totals 58 registered trials; most-linked intervention Placebo; top US site state Arizona. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.