Boston Children's Hospital

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Boston Children's Hospital sits in the top decile of US sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count).

462 total trials 110 currently recruiting 268 completed early-phase tilt top decile by trial count

Boston Children's Hospital: 462 sponsored US clinical trials, 110 recruiting.

Boston Children's Hospital sponsors 462 registered US clinical trials on ClinicalTrials.gov, 110 of them currently recruiting, and 268 completed. 35 of these trials are in Phase 3-4 (later-stage) and 53 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Congenital Heart Disease, with 9 trials.

Top-decile sponsor footprint

Boston Children's Hospital ranks in the top decile of sponsors by registered trial count (#77 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

D 61/100

268 of 303 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (88.4%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

462 total, page 1 of 10

RECRUITING Phase 4

Propofol-Only Versus Dexmedetomidine-Propofol in Children Undergoing Magnetic Resonance Imaging

NCT07369128

RECRUITING NA

Piloting the Competence in Romance and Understanding Sexual Health Curriculum

NCT07406100

RECRUITING

Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient

NCT07184476

RECRUITING Phase 4

Hoffa's Fat Pad Impingement (HFPI)

NCT07255248

RECRUITING NA

Balancing Emotions and Electronics: A Pilot Intervention for Preschoolers

NCT07394166

RECRUITING

Genetics of Neonatal Encephalopathy and Related Disorders

NCT07165938

RECRUITING NA

Automated Inhaler Monitoring for Asthma Medication Usage

NCT06825871

RECRUITING Phase 4

The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 1)

NCT07303738

RECRUITING NA

OnTrackCF: Engagement, Feasibility, and Acceptability Study

NCT07031323

RECRUITING NA

Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study

NCT07100379

RECRUITING

Study of Oral Fluid Testing Approach

NCT06891235

RECRUITING NA

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

NCT06555939

RECRUITING NA

Striae Distensae Treatment Using Deep Skin Abrasion

NCT07087405

RECRUITING NA

Sonographic Assessment of Cricoid Pressure

NCT04190524

RECRUITING NA

Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine

NCT06471348

RECRUITING

Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery

NCT06721455

RECRUITING

Registry and Natural History of Epilepsy-Dyskinesia Syndromes

NCT06967727

RECRUITING Phase 2

Glycemic Regulation as Endometriosis Adjunct Treatment

NCT06611501

RECRUITING

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

NCT06683092

RECRUITING NA

GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)

NCT06356220

RECRUITING NA

TransHealthGUIDE: Transforming Health for Gender-Diverse Young Adults

NCT06177600

RECRUITING NA

Bedtime Stories: Tailored Sleep Health Messaging for Caregivers

NCT06618040

RECRUITING

Study of Normal Intestinal Development and Disease in Premature and Term Neonates

NCT06681129

RECRUITING Phase 4

Gastrointestinal Dysmotility on Aspiration Risk

NCT05455359

RECRUITING

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

NCT06434207

RECRUITING

Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)

NCT06593951

RECRUITING NA

PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity

NCT06364514

RECRUITING NA

A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures

NCT06056635

RECRUITING Phase 1

Use of Indocyanine Green (ICG) for the Diagnosis of Biliary Atresia

NCT07513038

RECRUITING

A Multicenter Pediatric Deep Brain Stimulation Registry

NCT06585618

RECRUITING

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

NCT06585605

RECRUITING

Spastic Paraplegia - Centers of Excellence Research Network

NCT06553976

RECRUITING NA

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

NCT05899166

RECRUITING NA

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

NCT06326983

RECRUITING NA

Allogeneic Valve Transplantation

NCT06387446

RECRUITING NA

Randomized Controlled Crossover Trial of Postpyloric Feedings to Improve Pulmonary Outcomes in High-risk Preterm Infants

NCT05777512

RECRUITING NA

Language During Inhalational Induction

NCT06324955

RECRUITING NA

Biomarkers Research in Anxiety for Validation and Efficacy

NCT06221176

RECRUITING NA

The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now

NCT05591066

RECRUITING Phase 1

Hydrogen's Feasibility and Safety as a Therapy in ECPR

NCT05574296

RECRUITING NA

Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume

NCT03741777

RECRUITING NA

Clinical Trial of Blenderized Tube Feeds Varying in Viscosity

NCT05417958

RECRUITING

Implementation of a Consensus-Based Discharge Protocol for Preterm Infants With Lung Disease

NCT05285345

RECRUITING

CGM-Assisted Management of PN

NCT05902104

RECRUITING Phase 3

Oral Ketamine for Treatment of Vaso-Occlusive Pain

NCT05378555

RECRUITING NA

Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences

NCT05407129

RECRUITING Early Phase 1

Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study

NCT05744934

RECRUITING NA

PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS

NCT05296096

RECRUITING

Gastric Assessment of Pediatric Patients Undergoing Surgery

NCT05674643

RECRUITING NA

Immune Responses to Gluten

NCT05209568

Page 1 of 10 Next →

Phase Distribution

PhaseTrial count
Phase 1 30
Phase 2 23
Phase 3 12
Phase 4 23

What is open in the Boston Children's Hospital pipeline

110 recruiting of 462 indexed (24% open); 268 completed (58%).

Phase mix: 35 late (III/IV) vs 53 early (I/II) (early-phase heavy).

Top condition: Congenital Heart Disease (9 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Boston Children's Hospital: open-pipeline peers nationwide

Peers matched on 462 registered trials and 24% open enrollment, not the therapeutic-area sidebar.

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0200400600 5%10%15%20%25% Total trials Recruiting share Boston Children's HospitalUniversity of VirginiaMedical College of WisconsinAlliance for Clinical Trials in OncologyFred Hutchinson Cancer CenterAdventHealth Translational Research InstituteAuburn UniversityChugai PharmaceuticalHALEON
Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Boston Children's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 462 trials (± recruiting share)

Sponsors near 24% open enrollment (± trial volume)

What to do with this Boston Children's Hospital page

462 registered trials is a research-attention snapshot, not an endorsement of Boston Children's Hospital or any single study.

  • 110 of Boston Children's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Congenital Heart Disease is the condition Boston Children's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Congenital Heart Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Boston Children's Hospital pipeline card: 462 registered trials from official public datasets.Report a data error.