Boston Children's Hospital
Trial Pipeline
Hoffa's Fat Pad Impingement (HFPI)
NCT07255248
Balancing Emotions and Electronics: A Pilot Intervention for Preschoolers
NCT07394166
Genetics of Neonatal Encephalopathy and Related Disorders
NCT07165938
Automated Inhaler Monitoring for Asthma Medication Usage
NCT06825871
The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 1)
NCT07303738
OnTrackCF: Engagement, Feasibility, and Acceptability Study
NCT07031323
Study of Oral Fluid Testing Approach
NCT06891235
Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease
NCT06555939
Sonographic Assessment of Cricoid Pressure
NCT04190524
Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine
NCT06471348
Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery
NCT06721455
Registry and Natural History of Epilepsy-Dyskinesia Syndromes
NCT06967727
Glycemic Regulation as Endometriosis Adjunct Treatment
NCT06611501
Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)
NCT06683092
GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)
NCT06356220
TransHealthGUIDE: Transforming Health for Gender-Diverse Young Adults
NCT06177600
Bedtime Stories: Tailored Sleep Health Messaging for Caregivers
NCT06618040
Gastrointestinal Dysmotility on Aspiration Risk
NCT05455359
Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis
NCT06434207
Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)
NCT06593951
PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity
NCT06364514
A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures
NCT06056635
A Multicenter Pediatric Deep Brain Stimulation Registry
NCT06585618
A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes
NCT06585605
Spastic Paraplegia - Centers of Excellence Research Network
NCT06553976
Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes
NCT05899166
Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery
NCT06326983
Allogeneic Valve Transplantation
NCT06387446
Language During Inhalational Induction
NCT06324955
Biomarkers Research in Anxiety for Validation and Efficacy
NCT06221176
The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now
NCT05591066
Hydrogen's Feasibility and Safety as a Therapy in ECPR
NCT05574296
Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume
NCT03741777
Clinical Trial of Blenderized Tube Feeds Varying in Viscosity
NCT05417958
CGM-Assisted Management of PN
NCT05902104
Oral Ketamine for Treatment of Vaso-Occlusive Pain
NCT05378555
Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences
NCT05407129
Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study
NCT05744934
PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS
NCT05296096
Gastric Assessment of Pediatric Patients Undergoing Surgery
NCT05674643
Immune Responses to Gluten
NCT05209568
Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children
NCT05464186
Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome
NCT05528744
The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults
NCT05258981
Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery
NCT04299828
Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)
NCT05354622
Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis
NCT04380740
Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease
NCT05241418
VIGOR: Virtual Genome Center for Infant Health
NCT05205356
Advanced SPinal Innovations With Robotics and Enabling Technology Registry
NCT05071144
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
NCT04439552
Genetic Studies of Strabismus, Nystagmus, and Associated Disorders
NCT04770519
Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis
NCT06701084
Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology
NCT04900597
Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia
NCT04504227
Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event
NCT04477460
Low Dose IL-2 for the Treatment of Crohn's Disease
NCT04263831
Psychological Response and Readiness Associated With OCD of the Knee
NCT04649905
Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism
NCT04455906
High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy
NCT04331639
Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures
NCT04604418
Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis
NCT04103281
Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis
NCT04103268
Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia
NCT04712812
Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure
NCT04629014
Effects of Ketosis on Brain Function in Patients With T1DM
NCT04219709
Very Low Carbohydrate Diets and Glucagon Response in T1DM
NCT04200391
Type 1 Diabetes Management Using a Very Low Carbohydrate Versus Standard Diet
NCT03710928
A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease
NCT04166526
Optimizing Family Counseling for Anticipated Extremely Preterm Delivery
NCT03819933
Application of a Systematic Developmental Assessment to a Novel Population: Infants With Rare Genetic Disorders
NCT03967743
Impact of Thrombocytopenia and Platelet Transfusions on Neonatal Bleeding and Inflammation
NCT03848923
The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric
NCT03054831
Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present
NCT03655665
Developing Fast Pediatric Imaging
NCT03761121
Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support
NCT03593408
Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency
NCT03758521
A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB
NCT03530852
Angelman Syndrome Natural History Study
NCT04507997
Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation
NCT03532399
Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients
NCT03431064
Transplantation of Autologously Derived Mitochondria Following Ischemia
NCT02851758
Advanced Fetal Imaging - Phase II
NCT02840019
Shwachman Diamond Syndrome Registry and Study
NCT06056908
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
NCT02461446
Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia
NCT02793999
NIRS Monitoring in Premature Infants
NCT02601339
Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients
NCT02044497
MRI Assessment of Placental Health
NCT02297724
Lymphatic Anomalies Registry for the Assessment of Outcome Data
NCT02399527
Genetics of Epilepsy and Related Disorders
NCT01858285
Gene Discovery Core, The Manton Center
NCT02743845
Preterm Lung Patient Registry
NCT00951366
Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
NCT00499317
Identifying Genetic Causes of IC/BPS
NCT00389142
Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies
NCT03059420
Molecular and Genetic Studies of Congenital Myopathies
NCT00272883
Molecular Analysis of Patients With Neuromuscular Disease
NCT00390104
Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children
NCT06731660
Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children
NCT05687292
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 42 |
| Phase 2 | 7 |
| Phase 3 | 4 |
| Phase 4 | 35 |
Therapeutic Areas
What the Pipeline for Boston Children's Hospital Shows
According to the ClinicalTrials.gov registry, Boston Children's Hospital is linked to 752 US clinical trials across every stage of research activity. Of those, 665 studies are currently recruiting — about 88% of the sponsor's indexed portfolio — and 61 are already marked complete, representing roughly 8% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Boston Children's Hospital reports 39 late-stage studies (Phase 3 and Phase 4 combined) and 49 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Boston Children's Hospital is Congenital Heart Disease with 9 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.