Boston Children's Hospital

752 total trials 665 currently recruiting 61 completed

Trial Pipeline

RECRUITING Phase 4

Hoffa's Fat Pad Impingement (HFPI)

NCT07255248

RECRUITING NA

Balancing Emotions and Electronics: A Pilot Intervention for Preschoolers

NCT07394166

RECRUITING

Genetics of Neonatal Encephalopathy and Related Disorders

NCT07165938

RECRUITING NA

Automated Inhaler Monitoring for Asthma Medication Usage

NCT06825871

RECRUITING Phase 4

The Use of High Bile-binding Foods to Reduce Upper Gastrointestinal Bile Acid Concentrations (Aim 1)

NCT07303738

RECRUITING NA

OnTrackCF: Engagement, Feasibility, and Acceptability Study

NCT07031323

RECRUITING

Study of Oral Fluid Testing Approach

NCT06891235

RECRUITING NA

Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease

NCT06555939

RECRUITING NA

Sonographic Assessment of Cricoid Pressure

NCT04190524

RECRUITING NA

Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine

NCT06471348

RECRUITING

Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery

NCT06721455

RECRUITING

Registry and Natural History of Epilepsy-Dyskinesia Syndromes

NCT06967727

RECRUITING Phase 2

Glycemic Regulation as Endometriosis Adjunct Treatment

NCT06611501

RECRUITING

Restarting Triple Therapy With Robust Monitoring for Adverse Events (RETRIAL)

NCT06683092

RECRUITING NA

GF-NOURISH (Gluten Free Nutrition Optimization Through Ultra-processed Food Reduction and Improved Strategies for Health)

NCT06356220

RECRUITING NA

TransHealthGUIDE: Transforming Health for Gender-Diverse Young Adults

NCT06177600

RECRUITING NA

Bedtime Stories: Tailored Sleep Health Messaging for Caregivers

NCT06618040

RECRUITING Phase 4

Gastrointestinal Dysmotility on Aspiration Risk

NCT05455359

RECRUITING

Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis

NCT06434207

RECRUITING

Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)

NCT06593951

RECRUITING NA

PICNIC Study - PatIent Centered aNtIbiotic Courses in Children With Medical Complexity

NCT06364514

RECRUITING NA

A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures

NCT06056635

RECRUITING

A Multicenter Pediatric Deep Brain Stimulation Registry

NCT06585618

RECRUITING

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

NCT06585605

RECRUITING

Spastic Paraplegia - Centers of Excellence Research Network

NCT06553976

RECRUITING NA

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes

NCT05899166

RECRUITING NA

Opioid Sparing Anesthesia Care for Pediatric Patients Having Tonsil Surgery

NCT06326983

RECRUITING NA

Allogeneic Valve Transplantation

NCT06387446

RECRUITING NA

Language During Inhalational Induction

NCT06324955

RECRUITING NA

Biomarkers Research in Anxiety for Validation and Efficacy

NCT06221176

RECRUITING NA

The Patient and Family Centered I-PASS LISTEN Study: Language, Inclusion, Safety, and Teamwork for Equity Now

NCT05591066

RECRUITING Phase 1

Hydrogen's Feasibility and Safety as a Therapy in ECPR

NCT05574296

RECRUITING NA

Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume

NCT03741777

RECRUITING NA

Clinical Trial of Blenderized Tube Feeds Varying in Viscosity

NCT05417958

RECRUITING

CGM-Assisted Management of PN

NCT05902104

RECRUITING Phase 3

Oral Ketamine for Treatment of Vaso-Occlusive Pain

NCT05378555

RECRUITING NA

Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences

NCT05407129

RECRUITING Early Phase 1

Interstage Monitoring Using an Implantable Loop Recorder: A Pilot Study

NCT05744934

RECRUITING NA

PRotein Optimization With eXercise to Improve MUscle Mass and Functional outcomeS

NCT05296096

RECRUITING

Gastric Assessment of Pediatric Patients Undergoing Surgery

NCT05674643

RECRUITING NA

Immune Responses to Gluten

NCT05209568

RECRUITING NA

Effects of Whole vs. Nonfat Milk Consumption on Body Composition in Children

NCT05464186

RECRUITING

Delineating the Molecular Spectrum and the Clinical, Imaging and Neuronal Phenotype of Chopra-Amiel-Gordon Syndrome

NCT05528744

RECRUITING NA

The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults

NCT05258981

RECRUITING

Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery

NCT04299828

RECRUITING

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

NCT05354622

RECRUITING Phase 2

Extended vs Short-term Abatacept Dosing for Graft Versus Host Disease Prophylaxis

NCT04380740

RECRUITING

Atrial Late Gadolinium Enhancement in Patients with Repaired Congenital Heart Disease

NCT05241418

RECRUITING

VIGOR: Virtual Genome Center for Infant Health

NCT05205356

RECRUITING

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

NCT05071144

RECRUITING

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

NCT04439552

RECRUITING

Genetic Studies of Strabismus, Nystagmus, and Associated Disorders

NCT04770519

RECRUITING NA

Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis

NCT06701084

RECRUITING NA

Effect of Blenderized Enteral Tube Feeds on Pediatric Upper Gastrointestinal Tract Physiology

NCT04900597

RECRUITING NA

Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

NCT04504227

RECRUITING

Effect of Thickened Feeds on Clinical Outcomes in Children With Brief Resolved Unexplained Event

NCT04477460

RECRUITING Phase 1

Low Dose IL-2 for the Treatment of Crohn's Disease

NCT04263831

RECRUITING

Psychological Response and Readiness Associated With OCD of the Knee

NCT04649905

RECRUITING

Mechanisms of Increased Disease Severity in AD Patients With the IL-4Ra R576 Polymorphism

NCT04455906

RECRUITING

High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy

NCT04331639

RECRUITING

Outcomes and Health Care Resource Utilization in Pediatric Congenital Heart Disease Patients Undergoing Non-Cardiac Procedures

NCT04604418

RECRUITING

Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis

NCT04103281

RECRUITING

Neutrophil Phenotypic Profiling and Organ Injury Assessment in Patients With Sepsis

NCT04103268

RECRUITING

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

NCT04712812

RECRUITING

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

NCT04629014

RECRUITING NA

Effects of Ketosis on Brain Function in Patients With T1DM

NCT04219709

RECRUITING NA

Very Low Carbohydrate Diets and Glucagon Response in T1DM

NCT04200391

RECRUITING NA

Type 1 Diabetes Management Using a Very Low Carbohydrate Versus Standard Diet

NCT03710928

RECRUITING

A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease

NCT04166526

RECRUITING NA

Optimizing Family Counseling for Anticipated Extremely Preterm Delivery

NCT03819933

RECRUITING

Application of a Systematic Developmental Assessment to a Novel Population: Infants With Rare Genetic Disorders

NCT03967743

RECRUITING

Impact of Thrombocytopenia and Platelet Transfusions on Neonatal Bleeding and Inflammation

NCT03848923

RECRUITING Phase 4

The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric

NCT03054831

RECRUITING Phase 4

Does Topical Otic Drop Use at Time of Tympanostomy Tube Surgery Improve Outcomes When no Middle Ear Effusion is Present

NCT03655665

RECRUITING NA

Developing Fast Pediatric Imaging

NCT03761121

RECRUITING

Pharmacokinetics of Sedatives and Analgesics During Extracorporeal Membrane Oxygenation (ECMO) Support

NCT03593408

RECRUITING

Natural History Study of Patients With Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency

NCT03758521

RECRUITING NA

A 90 Day, Phase 3,Open Labeled Exploratory Study of RELiZORB

NCT03530852

RECRUITING

Angelman Syndrome Natural History Study

NCT04507997

RECRUITING

Pharmacokinetics of Bivalirudin for Pediatric Anticoagulation

NCT03532399

RECRUITING

Lung Recruitment Maneuver as a Potential Predictor of Fluid Responsiveness in Mechanically Ventilated Pediatric Patients

NCT03431064

RECRUITING NA

Transplantation of Autologously Derived Mitochondria Following Ischemia

NCT02851758

RECRUITING NA

Advanced Fetal Imaging - Phase II

NCT02840019

RECRUITING

Shwachman Diamond Syndrome Registry and Study

NCT06056908

RECRUITING

Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations

NCT02461446

RECRUITING

Perinatal Brain Injury: Potential of Innovative NIRS to Optimize Hypothermia

NCT02793999

RECRUITING

NIRS Monitoring in Premature Infants

NCT02601339

RECRUITING Phase 4

Population Pharmacokinetics and Pharmacogenomics of Oral Oxycodone in Pediatric Surgical Patients

NCT02044497

RECRUITING

MRI Assessment of Placental Health

NCT02297724

RECRUITING

Lymphatic Anomalies Registry for the Assessment of Outcome Data

NCT02399527

RECRUITING

Genetics of Epilepsy and Related Disorders

NCT01858285

RECRUITING

Gene Discovery Core, The Manton Center

NCT02743845

RECRUITING

Preterm Lung Patient Registry

NCT00951366

RECRUITING

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

NCT00499317

RECRUITING

Identifying Genetic Causes of IC/BPS

NCT00389142

RECRUITING

Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies

NCT03059420

RECRUITING

Molecular and Genetic Studies of Congenital Myopathies

NCT00272883

RECRUITING

Molecular Analysis of Patients With Neuromuscular Disease

NCT00390104

ACTIVE NOT RECRUITING NA

Digital Otoscope Versus Education and Feedback for Otitis Media in Young Children

NCT06731660

ACTIVE NOT RECRUITING

Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery in Children

NCT05687292

Phase Distribution

PhaseTrial count
Phase 1 42
Phase 2 7
Phase 3 4
Phase 4 35

What the Pipeline for Boston Children's Hospital Shows

According to the ClinicalTrials.gov registry, Boston Children's Hospital is linked to 752 US clinical trials across every stage of research activity. Of those, 665 studies are currently recruiting — about 88% of the sponsor's indexed portfolio — and 61 are already marked complete, representing roughly 8% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

The phase mix for Boston Children's Hospital reports 39 late-stage studies (Phase 3 and Phase 4 combined) and 49 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

The top therapeutic focus area indexed for Boston Children's Hospital is Congenital Heart Disease with 9 linked trials, and 9 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial