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NCT03054922 · ClinicalTrials.gov registry record · Phase 3
Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables
A Phase 3 study of Anesthesia, sponsored by Nationwide Children's Hospital.
- Completed
- Registry status
- Phase 3
- Development phase
- 59
- Enrollment target
- 1
- Study location
NCT03054922: Completed Phase 3 study of Anesthesia, sponsored by Nationwide Children's Hospital.
NCT03054922 is a Phase 3 study of Anesthesia that has completed, run by Nationwide Children's Hospital. The registered enrollment target is 59 participants, below the 109,409-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03054922, a Phase 3 study of Anesthesia, has completed, sponsored by Nationwide Children's Hospital.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 59 participants
- Enrollment target
- 1
- Study location
Study Summary
During major surgical procedures, intravascular volume is maintained with the administration of isotonic fluids such as Lactated Ringers (LR), Normal Saline (NS) or Normosol-R. All three of these fluids are in common clinical use for this purpose. As large volumes of NS may result in a dilutional acidosis and an increasing base deficit, it may cloud clinical decision making when resuscitative efforts are guided by acid-base status on routine arterial blood gas analysis. This is a prospective, randomized study to evaluate changes in acid-base and electrolyte (sodium, potassium, calcium) status with the use of various isotonic fluids for intraoperative resuscitation.
Primary Outcome
Change in base deficit from 1st to 2nd blood gas to measure metabolic acidosis
Conditions Studied
Interventions
- DRUG Normal Saline
- DRUG Lactated Ringer
- DRUG Normosol-R Inj
Study Locations (1)
Ohio
- Nationwide Children's Hospital - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 59 participants |
| Start Date | 2017-02-23 |
| Est. Completion | 2018-09-30 |
| Phase | Phase 3 |
What the finished NCT03054922 record still lists
NCT03054922 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 59 participants, a relatively small participant target, below the 109,409-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Anesthesia appearing as the primary indexed condition, and to 3 interventions - of which Normal Saline is the first listed.
NCT03054922 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT03054922 about?
NCT03054922 is a clinical study titled "Impact of Intraoperative Fluid Management on Electrolyte and Acid-base Variables". During major surgical procedures, intravascular volume is maintained with the administration of isotonic fluids such as Lactated Ringers (LR), Normal Saline (NS) or Normosol-R. All three of these fluids are in common clinical use for this purpose. As large volumes of NS may result in a dilutional ac...
What is the current status of trial NCT03054922?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 59 participants. The study started on 2017-02-23. Estimated completion is 2018-09-30.
What conditions does trial NCT03054922 study?
This clinical trial studies the following conditions: Anesthesia.
What interventions are being tested in trial NCT03054922?
The interventions under investigation include: Normal Saline (DRUG), Lactated Ringer (DRUG), Normosol-R Inj (DRUG).
Who is sponsoring clinical trial NCT03054922?
This trial is sponsored by Nationwide Children's Hospital, which has 188 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03054922 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anesthesia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03054922's enrollment target sits among peer trials
59 32nd of 57 higher than 26 of 57 other Anesthesia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anesthesia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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