Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Non-alcoholic Fatty Liver Disease
Open-data reference.
17 US clinical trials · 2 currently recruiting
Active & Recent Trials
A Clinical Study to Investigate the Safety and Tolerability of Efimosfermin Alfa Injection in Participants With Known or Suspected F2- or F3-stage MASH
GlaxoSmithKline
NCT07221188
A Pivotal Clinical Study to Investigate Efimosfermin Alfa in Participants With Biopsy-confirmed F2- or F3-stage MASH
GlaxoSmithKline
NCT07221227
Phase 2b Study of GSK4532990 in Adults With NASH
GlaxoSmithKline
NCT05583344
Role of Immune System in Obesity-related Inflammation and Cardiometabolic Risk
Washington University School of Medicine
NCT01104220
A Clinical Study of Efinopegdutide in People With Compensated Cirrhosis Due to Steatohepatitis (MK-6024-017)
Merck Sharp & Dohme
NCT06465186
A Study to Evaluate the Safety, Tolerability & Efficacy of MSDC-0602K in Patients With NASH
Cirius Therapeutics
NCT02784444
Nonalcoholic Fatty Liver Disease and Atherosclerotic Risk in Children
Augusta University
NCT02383485
Alternate Dosing Study of MK-6024 in Adults With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) (MK-6024-016)
Merck Sharp & Dohme
NCT06482112
A Study to Test How Well Different Doses of BI 3006337 Are Tolerated by People With Overweight or Obesity and With Fatty Liver Disease
Boehringer Ingelheim
NCT05970640
6-week Safety and PD Study in Adults With NAFLD
Pfizer
NCT03256526
Sitagliptin Versus Placebo in the Treatment of Non-alcoholic Fatty Liver Disease
University of California, San Diego
NCT01963845
Single Ascending Dose of AMG 609 in Participants With Non-alcoholic Fatty Liver Disease
Amgen
NCT04857606
De Novo Lipogenesis, Lipid and Carbohydrate Metabolism in Non-alcoholic Fatty Liver Disease
University of California, San Francis
NCT00714129
Effect of Macrocomposition on Nonalcoholic Fatty Liver Disease (NAFLD) in Bariatric Surgery Candidates
University of Michigan
NCT00887393
Early Intervention and Prevention of Non-Alcoholic Fatty Liver Disease in Adolescents
University of Wisconsin, Madison
NCT02116192
Autonomic Dysfunction in Non-Alcoholic Fatty Liver Disease
Virginia Commonwealth University
NCT02132780
Endoscopic Ultrasound(EUS)-Guided TRUCUT Biopsy (EUS-TCB) of Suspected Nonalcoholic Fatty Liver Disease(NAFLD.)
Indiana University
NCT00586313
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 2 |
| Phase 2 | 6 |
| Phase 3 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Non-alcoholic Fatty Liver Disease Trial Landscape
ClinicalTrials.gov lists 17 US studies indexed under Non-alcoholic Fatty Liver Disease, and 2 of those are currently open to recruitment — roughly 12% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Non-alcoholic Fatty Liver Disease shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 8 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Non-alcoholic Fatty Liver Disease is led by GlaxoSmithKline with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 17 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Non-alcoholic Fatty Liver Disease?
PlainTrial tracks 17 US clinical trials for Non-alcoholic Fatty Liver Disease, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Non-alcoholic Fatty Liver Disease?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.