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NCT06403852 · ClinicalTrials.gov registry record · Phase 2
Investigating Near-Threshold Perception During Anesthetic Sedation
A Phase 2 study of Anesthesia and fMRI, sponsored by University of Michigan.
- Completed
- Registry status
- Phase 2
- Development phase
- 36
- Enrollment target
- 1
- Study location
NCT06403852: Completed Phase 2 study of Anesthesia and fMRI, sponsored by University of Michigan.
NCT06403852 is a Phase 2 study of Anesthesia and fMRI that has completed, run by University of Michigan. The registered enrollment target is 36 participants, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06403852, a Phase 2 study of Anesthesia and fMRI, has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 36 participants
- Enrollment target
- 1
- Study location
Study Summary
The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia, and to evaluate if the use of ultrasonic brain stimulation accelerates return to consciousness. Propofol is FDA approved for use in patients undergoing an anesthetic for medical treatment but is not approved for use in healthy volunteers.
Primary Outcome
Visual stimuli evoked activity was quantified by measurements of the fMRI BOLD signal. Neural response to a natural visual stimulus will be assessed during both conscious and anesthetized states.
Conditions Studied
Interventions
- COMBINATION_PRODUCT Functional Magnetic Resonance Imaging (fMRI) with propofol
Study Locations (1)
Michigan
- University of Michigan - Ann Arbor
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2024-05-10 |
| Est. Completion | 2025-10-03 |
| Phase | Phase 2 |
What the finished NCT06403852 record still lists
NCT06403852 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Anesthesia appearing as the primary indexed condition, and to 1 intervention - of which Functional Magnetic Resonance Imaging (fMRI) with propofol is the first listed.
NCT06403852 reports a single indexed study location in Michigan.
Frequently Asked Questions
What is clinical trial NCT06403852 about?
NCT06403852 is a clinical study titled "Investigating Near-Threshold Perception During Anesthetic Sedation". The researchers expect to gain a deeper understanding of mental function during different levels of anesthesia, and to evaluate if the use of ultrasonic brain stimulation accelerates return to consciousness. Propofol is FDA approved for use in patients undergoing an anesthetic for medical treatment...
What is the current status of trial NCT06403852?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 36 participants. The study started on 2024-05-10. Estimated completion is 2025-10-03.
What conditions does trial NCT06403852 study?
This clinical trial studies the following conditions: Anesthesia, fMRI, Propofol.
What interventions are being tested in trial NCT06403852?
The interventions under investigation include: Functional Magnetic Resonance Imaging (fMRI) with propofol (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT06403852?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06403852 being conducted?
This trial has 1 study location across Michigan. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Anesthesia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06403852's enrollment target sits among peer trials
36 43rd of 57 higher than 15 of 57 other Anesthesia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Anesthesia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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