Eli Lilly and Company

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Eli Lilly and Company sits in the top decile of US sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count).

1,341 total trials 124 currently recruiting 1029 completed early-phase tilt top decile by trial count

Eli Lilly and Company: 1,341 sponsored US clinical trials, 124 recruiting.

Eli Lilly and Company sponsors 1,341 registered US clinical trials on ClinicalTrials.gov, 124 of them currently recruiting, and 1,029 completed. 459 of these trials are in Phase 3-4 (later-stage) and 861 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 55 trials.

Top-decile sponsor footprint

Eli Lilly and Company ranks in the top decile of sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 67/100

1,029 of 1,131 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,341 total, page 6 of 27

COMPLETED Phase 1

A Study of Carbon-14-Labelled [14C] LY3871801 in Healthy Male Participants

NCT06049108

COMPLETED Phase 1

A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese

NCT06039826

COMPLETED Phase 1

A Study to Evaluate the Effect of Food on LOXO-783 in Healthy Participants

NCT06028425

COMPLETED Phase 1

A Research Study Looking at Similarity Between LY3437943 Versions for Different Injection Devices

NCT06003465

TERMINATED Phase 1

A Study of LY3885125 in Participants With Dyslipidemia or Non-Alcoholic Fatty Liver Disease (NAFLD)

NCT06007651

COMPLETED Phase 1

A Study of LY3871801 in Healthy Asian and Non-Asian Participants

NCT05960851

COMPLETED Phase 3

A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone

NCT05971940

COMPLETED Phase 3

A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee

NCT05931367

COMPLETED Phase 1

A Study of Tirzepatide (LY3298176) in Healthy Lactating Females

NCT05978713

COMPLETED Phase 1

A Drug Drug Interaction (DDI) Study of Selpercatinib (LY3527723) and Rosuvastatin in Healthy Participants

NCT05906836

COMPLETED Phase 1

A Relative Bioavailability Study of Peresolimab (LY3462817) Formulations in Healthy Participants

NCT05959109

COMPLETED Phase 2

A Study of Retatrutide (LY3437943) on Renal Function in Participants With Overweight or Obesity and Chronic Kidney Disease With or Without Type 2 Diabetes

NCT05936151

COMPLETED Phase 1

A Study of LY3437943 in Healthy Participants With a High Body Mass Index

NCT05959096

COMPLETED Phase 1

A Study of LY3437943 in Participants With Impaired and Normal Liver Function

NCT05916560

COMPLETED Phase 1

A Phase 1, Parallel, Single-Dose, Open-Label, Single-Period Study of LY3502970 in Participants With Normal Renal Function and Participants With Renal Impairment.

NCT05936138

TERMINATED Phase 2

A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis

NCT05911841

COMPLETED Phase 1

A Study of LY3502970 in Participants With Impaired and Normal Liver Function

NCT05882032

COMPLETED Phase 1

A Study of LY3532226 in Participants With Type 1 Diabetes Mellitus

NCT05887999

COMPLETED Phase 1

A Study to Evaluate the Effect of Cholestyramine on LOXO-783 in Healthy Participants

NCT05894928

COMPLETED Phase 3

A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes

NCT05872620

COMPLETED Phase 1

A Study of [14C]-LY3537982 in Healthy Participants

NCT05901311

COMPLETED Phase 1

A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy Participants

NCT05860933

COMPLETED Phase 1

A Multiple Dose Study of LY3502970 in Healthy Overweight and Obese Participants

NCT05841238

COMPLETED Phase 1

A Study of LY3819469 in Participants With Impaired and Normal Renal Function

NCT05841277

COMPLETED Phase 3

A Study of Tirzepatide (LY3298176) in Participants With Obesity or Overweight With Weight Related Comorbidities

NCT05822830

COMPLETED Phase 1

A Study of the Effect of Food on LY3537982 in Healthy Participants

NCT05824858

COMPLETED Phase 1

A Research Study Looking at Similarity Between Tirzepatide Versions for Different Injection Devices

NCT05810597

COMPLETED Phase 1

A Study of LY3473329 in Participants With Impaired and Normal Renal Function

NCT05778864

COMPLETED Phase 1

A Study of Carbon-14-Labelled [14C] LY3437943 in Healthy Male Participants

NCT05757531

COMPLETED Phase 4

A Study of Tirzepatide (LY3298176) in Adults With Type 2 Diabetes Switching From a GLP-1 RA (SURPASS-SWITCH-2)

NCT05706506

COMPLETED Phase 1

A Study of Carbon-14-Labelled [14C] LY3372689 in Healthy Male Participants

NCT05749848

COMPLETED Phase 1

A Study of LY3848575 in Healthy Participants

NCT05727072

COMPLETED Phase 1

A Study of Tirzepatide (LY3298176) in Pediatric Participants With Obesity

NCT05696847

TERMINATED Phase 2

A Study of LY3540378 in Participants With Worsening Chronic Heart Failure With Preserved Ejection Fraction (HFpEF)

NCT05592275

COMPLETED Phase 3

A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time (QWINT-1)

NCT05662332

COMPLETED Phase 3

A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color

NCT05372419

COMPLETED Phase 3

A Study of Lebrikizumab (LY3650150) in Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis Previously Treated With Dupilumab

NCT05369403

COMPLETED Phase 2

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Chronic Low Back Pain

NCT05630196

COMPLETED Phase 1

A Bioequivalence Study of Mirikizumab (LY3074828) Solution in Healthy Participants

NCT05644353

COMPLETED Phase 4

A Study of Tirzepatide (LY3298176) in Adult Participants With Type 2 Diabetes Switching From Dulaglutide (SURPASS-SWITCH)

NCT05564039

COMPLETED Phase 2

A Study of LY3473329 in Adult Participants With Elevated Lipoprotein(a) at High Risk for Cardiovascular Events

NCT05563246

COMPLETED Phase 2

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 In Participants With Osteoarthritis Pain

NCT05620563

COMPLETED Phase 2

Safety and Efficacy of Bimagrumab and Semaglutide in Adults Who Are Overweight or Obese

NCT05616013

COMPLETED Phase 1

A Study of LY3437943 in Healthy Participants and Participants With Impaired Renal Function

NCT05611957

COMPLETED Phase 1

A Study of LY3305677 in Participants With Obesity Or Overweight

NCT05623839

COMPLETED Phase 1

A Study of Effect of LY3556050 on Metformin in Healthy Participants

NCT05615467

COMPLETED Phase 2

A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05).

NCT05620576

COMPLETED Phase 1

A Study of LY3457263 in Obese Participants

NCT05582096

COMPLETED Phase 1

A Drug Interaction Study of LY3871801 in Healthy Participants

NCT05602675

COMPLETED Phase 2

A Study of LY3819469 in Participants With Elevated Lipoprotein(a) [Lp(a)]

NCT05565742

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Phase Distribution

PhaseTrial count
Phase 1 517
Phase 2 344
Phase 3 368
Phase 4 91

What is open in the Eli Lilly and Company pipeline

124 recruiting of 1,341 indexed (9% open); 1,029 completed (77%).

Phase mix: 459 late (III/IV) vs 861 early (I/II) (early-phase heavy).

Top condition: Healthy (55 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Eli Lilly and Company: open-pipeline peers nationwide

Peers matched on 1,341 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15% Total trials Recruiting share Eli Lilly and CompanyGlaxoSmithKlineUniversity of MichiganNovartis PharmaceuticalsAstraZenecaShionogiUniversity of KentuckyUniversity of VermontLahey Clinic
Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,341 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this Eli Lilly and Company page

1,341 registered trials is a research-attention snapshot, not an endorsement of Eli Lilly and Company or any single study.

  • 124 of Eli Lilly and Company's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition Eli Lilly and Company studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Eli Lilly and Company pipeline card: 1,341 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.