Eli Lilly and Company

Open enrollment with an early-phase pipeline tilt

According to ClinicalTrials.gov-derived indexes, Eli Lilly and Company sits in the top decile of US sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count).

1,341 total trials 124 currently recruiting 1029 completed early-phase tilt top decile by trial count

Eli Lilly and Company: 1,341 sponsored US clinical trials, 124 recruiting.

Eli Lilly and Company sponsors 1,341 registered US clinical trials on ClinicalTrials.gov, 124 of them currently recruiting, and 1,029 completed. 459 of these trials are in Phase 3-4 (later-stage) and 861 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Healthy, with 55 trials.

Top-decile sponsor footprint

Eli Lilly and Company ranks in the top decile of sponsors by registered trial count (#18 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

C 67/100

1,029 of 1,131 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (91.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

1,341 total, page 5 of 27

ACTIVE NOT RECRUITING Phase 3

A Study of Abemaciclib (LY2835219) Combined With Fulvestrant in Women With Hormone Receptor Positive HER2 Negative Breast Cancer

NCT02107703

ACTIVE NOT RECRUITING Phase 1

A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread

NCT02057133

ACTIVE NOT RECRUITING Phase 2

A Study of LY2784544 in Participants With Myeloproliferative Neoplasms

NCT01594723

NOT YET RECRUITING Phase 3

A Study of Orforglipron (LY3502970) Compared With Dulaglutide in Pediatric Participants With Type 2 Diabetes

NCT07668336

NOT YET RECRUITING Phase 2

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Chronic Low Back Pain

NCT07641504

NOT YET RECRUITING Phase 2

A Chronic Pain Master Protocol (CPMP): A Study of LY4065967 in Participants With Osteoarthritis Pain

NCT07641517

NOT YET RECRUITING Phase 1

A Study of LY3971297 in Participants With Heart Failure

NCT07547540

NOT YET RECRUITING Phase 1

A Study of Food Effect on Tersolisib (LY4064809) in Healthy Participants

NCT07662798

NOT YET RECRUITING Phase 1

A Study of LY4174794 in Participants With Obesity or Overweight Who Are Otherwise Healthy

NCT07654972

NOT YET RECRUITING Phase 4

A Study to Measure Mirikizumab Levels in Breast Milk of Lactating Participants Receiving Mirikizumab Therapeutically for an Approved Indication

NCT07612267

COMPLETED Phase 1

A Study of [14C]-LY4064809 in Healthy Participants

NCT07519525

TERMINATED Phase 2

A Study of LY3549492 in Healthy Weight Adult Participants

NCT07085468

COMPLETED Phase 1

A Study of Remternetug (LY3372993) in Healthy Participants

NCT07056309

COMPLETED Phase 1

A Study of [14C]-LY4065967 in Healthy Participants

NCT07039045

TERMINATED Phase 2

A Study of LY3549492 in Adults With Obesity or Overweight With Type 2 Diabetes

NCT07030868

COMPLETED Phase 1

A Study of Eloralintide (LY3841136) and Eloralintide With Tirzepatide in Participants With Overweight or Obesity

NCT06916065

COMPLETED Phase 1

A Study of Bimagrumab Alone (LY3985863) and Bimagrumab With Tirzepatide (LY900042) in Healthy Participants

NCT06890611

COMPLETED Phase 1

A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight

NCT06824051

COMPLETED Phase 1

A Study of Olomorasib (LY3537982) in Participants With Hepatic Impairment and Healthy Participants

NCT06719128

COMPLETED Phase 1

A Drug-Drug Interaction Study of Orforglipron (LY3502970) With Quinidine in Healthy Participants

NCT06704763

COMPLETED Phase 1

A Study of [14C]-LY3866288 in Healthy Participants

NCT06644378

COMPLETED Phase 1

A Study of LY3866288 in Healthy Participants

NCT06641037

COMPLETED Phase 3

A Study of Orforglipron for the Maintenance of Body Weight Reduction in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities (ATTAIN-MAINTAIN)

NCT06584916

COMPLETED Phase 1

A Study of LY3532226 in Participants With Obesity

NCT06557356

COMPLETED NA

A Study of Subcutaneous Injection in Healthy Participants

NCT06516913

COMPLETED Phase 1

A Study to Compare Tablets and Capsules of Orforglipron (LY3502970) in Healthy Participants Who Are Obese or Overweight

NCT06440980

COMPLETED Phase 1

A Bioequivalence Study of Citrate Free Mirikizumab (LY3074828) in Healthy Participants

NCT06475729

COMPLETED Phase 1

A First-In-Human Study of LY3985297 in Healthy Participants

NCT06395012

COMPLETED Phase 3

Lebrikizumab Pen Ease of Use in Participants With Atopic Dermatitis

NCT06444165

COMPLETED Phase 1

A Drug-Drug Interaction (DDI) Study of Orforglipron With Carbamazepine in Healthy Participants

NCT06370728

COMPLETED Phase 3

Effect of Retatrutide Compared With Placebo in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone (TRANSCEND-T2D-1)

NCT06354660

COMPLETED Phase 1

A Study of LY3841136 in Overweight and Obese Participants

NCT06345066

COMPLETED Phase 1

A Study to Measure Calorie Consumption and Usage in Participants With Obesity Using LY3437943

NCT06313528

COMPLETED Phase 2

A Study of LY3841136 Compared With Placebo in Adult Participants With Obesity or Overweight

NCT06230523

COMPLETED Phase 1

Abemaciclib Plus Darolutamide in Prostate Cancer That Has Spread After Initial Treatment

NCT05999968

COMPLETED Phase 1

A Relative Bioavailability Study of LY3454738 in Healthy Participants

NCT06173895

COMPLETED Phase 3

A Study of Orforglipron (LY3502970) Compared With Dapagliflozin in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Metformin

NCT06192108

COMPLETED Phase 1

A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants

NCT06186622

COMPLETED Phase 2

A Study of LY3972406 in Adult Participants With Moderate-to-Severe Plaque Psoriasis

NCT06176768

COMPLETED Phase 1

A First-In-Human Study of LY3839840 in Healthy Participants

NCT06153355

COMPLETED Phase 2

A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight

NCT06124807

COMPLETED Phase 1

A Study to Investigate the Safety and Tolerability of LY3938577 in Healthy Participants and Participants With Type 2 Diabetes Mellitus

NCT06132126

COMPLETED Phase 3

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor

NCT06109311

TERMINATED Phase 1

A Study of LY3872386 in Healthy Participants and Participants With Atopic Dermatitis

NCT06119529

COMPLETED Phase 1

A Drug-Drug Interaction Study of LY3537982 on Midazolam, Digoxin, and Rosuvastatin in Healthy Participants

NCT06111521

COMPLETED Phase 1

A Study of [14C]-LOXO-783 in Healthy Adult Participants

NCT06102512

COMPLETED Phase 1

A Phase I Study of LY3502970 in Healthy Participants

NCT06085482

COMPLETED Phase 2

A Study of LY3556050 in Adult Participants With Diabetic Peripheral Neuropathic Pain

NCT06074562

COMPLETED Phase 3

A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin

NCT06045221

COMPLETED Phase 1

A Study of Carbon-14-Labelled [14C] LY3556050 in Healthy Male Participants

NCT06052462

← Previous Page 5 of 27 Next →

Phase Distribution

PhaseTrial count
Phase 1 517
Phase 2 344
Phase 3 368
Phase 4 91

What is open in the Eli Lilly and Company pipeline

124 recruiting of 1,341 indexed (9% open); 1,029 completed (77%).

Phase mix: 459 late (III/IV) vs 861 early (I/II) (early-phase heavy).

Top condition: Healthy (55 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

Eli Lilly and Company: open-pipeline peers nationwide

Peers matched on 1,341 registered trials and 9% open enrollment, not the therapeutic-area sidebar.

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05001,0001,500 0%5%10%15% Total trials Recruiting share Eli Lilly and CompanyGlaxoSmithKlineUniversity of MichiganNovartis PharmaceuticalsAstraZenecaShionogiUniversity of KentuckyUniversity of VermontLahey Clinic
Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

Eli Lilly and Company sits at or above the median trial volume and below the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 1,341 trials (± recruiting share)

Sponsors near 9% open enrollment (± trial volume)

What to do with this Eli Lilly and Company page

1,341 registered trials is a research-attention snapshot, not an endorsement of Eli Lilly and Company or any single study.

  • 124 of Eli Lilly and Company's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Healthy is the condition Eli Lilly and Company studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Healthy trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. Eli Lilly and Company pipeline card: 1,341 registered trials from official public datasets. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.