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NCT05372419 · ClinicalTrials.gov registry record · Phase 3
A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color
A Phase 3 study of Atopic Dermatitis, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 3
- Development phase
- 90
- Enrollment target
- 20
- Study locations
NCT05372419: Completed Phase 3 study of Atopic Dermatitis, sponsored by Eli Lilly and Company.
NCT05372419 is a Phase 3 study of Atopic Dermatitis that has completed, run by Eli Lilly and Company. The registered enrollment target is 90 participants, below the 609-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (85% lower). The trial reports 20 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05372419, a Phase 3 study of Atopic Dermatitis, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 90 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main purpose of this study is to determine the safety and efficacy lebrikizumab in adolescent and adult participants with moderate-to-severe atopic dermatitis (AD) and skin of color.
Primary Outcome
The EASI assesses objective physician estimates of 2 dimensions of atopic dermatitis - disease extent and clinical signs affected: 0 = 0%; 1 = 1-9%; 2 = 10-29%; 3 = 30-49%; 4 = 50-69%; 5 = 70-89%; 6 = 90-100% and the severity of 4 clinical signs: (1) erythema, (2) edema/papulation, (3) excoriation, and (4) lichenification each on a scale of 0 to 3 (0 = none, absent; 1 = mild; 2 = moderate; 3 = severe) at 4 body sites (head/neck, trunk, upper limbs, and lower limbs). Half scores are allowed betwe
Conditions Studied
Interventions
- DRUG Lebrikizumab
Study Locations (20)
California
- First OC Dermatology - Fountain Valley
- Center For Dermatology Clinical Research, Inc. - Fremont
- Axon Clinical Research - Inglewood
- Avance Clinical Trials Inc - Laguna Niguel
- Dermatology Research Associates - Los Angeles
- Wallace Medical Group, Inc. - Los Angeles
- Cura Clinical Research - Palmdale
- University of California Davis (UC Davis) Comprehensive Cancer Center - Sacramento
- Clinical Science Institute - Santa Monica
- Cura Clinical Research - Sherman Oaks
Florida
- Encore Medical Research of Boynton Beach - Boynton Beach
- Skin Care Research, Inc - Hollywood
- Solutions Through Advanced Research - Jacksonville
- Miami Dermatology and Laser Research - Miami
- Savin Medical Group, LLC - Miami Lakes
- PureSkin Dermatology - Orlando
Georgia
- Skin Care Physicians of Georgia - Macon
- Advanced Medical Research - Sandy Springs
Alabama
- Total Skin and Beauty Dermatology Center, PC - Birmingham
Connecticut
- UConn Health - Farmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2023-01-12 |
| Est. Completion | 2025-02-17 |
| Phase | Phase 3 |
What the finished NCT05372419 record still lists
NCT05372419 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 609-participant average among 150 other Atopic Dermatitis trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Atopic Dermatitis appearing as the primary indexed condition, and to 1 intervention - of which Lebrikizumab is the first listed.
NCT05372419 names 20 study sites across 5 states, led by California, Florida, Georgia.
Frequently Asked Questions
What is clinical trial NCT05372419 about?
NCT05372419 is a clinical study titled "A Study of (LY3650150) Lebrikizumab to Assess the Safety and Efficacy of Adult and Adolescent Participants With Moderate-to-Severe Atopic Dermatitis and Skin of Color". The main purpose of this study is to determine the safety and efficacy lebrikizumab in adolescent and adult participants with moderate-to-severe atopic dermatitis (AD) and skin of color.
What is the current status of trial NCT05372419?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 90 participants. The study started on 2023-01-12. Estimated completion is 2025-02-17.
What conditions does trial NCT05372419 study?
This clinical trial studies the following conditions: Atopic Dermatitis.
What interventions are being tested in trial NCT05372419?
The interventions under investigation include: Lebrikizumab (DRUG).
Who is sponsoring clinical trial NCT05372419?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05372419 being conducted?
This trial has 20 study locations across Alabama, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05372419's enrollment target sits among peer trials
90 90th of 150 higher than 58 of 150 other Atopic Dermatitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Atopic Dermatitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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