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A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05).
NCT05620576 · View on ClinicalTrials.gov ↗
Study Summary
This study is being done to test the safety and efficacy of the study drug LY3857210 for the treatment of diabetic peripheral neuropathic pain. This trial is part of the chronic pain master protocol H0P-MC-CPMP (NCT05986292) which is a protocol to accelerate the development of new treatments for chronic pain.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG LY3857210
Study Locations (20)
Florida
- Accel Research Sites- Clinical Research Unit — DeLand
- Suncoast Research Group — Miami
- University of Miami Don Suffer Clinical Research Building — Miami
- New Horizon Research Center — Miami
- Renstar Medical Research — Ocala
- Synexus Clinical Research US, Inc - Orlando — Orlando
- Synexus Clinical Research US, Inc. — Pinellas Park
Massachusetts
- Boston Clinical Trials — Boston
- ActivMed Practices and Research — Methuen
- MedVadis Research Corporation — Waltham
Arizona
- Synexus Clinical Research US, Inc. — Chandler
- Arizona Research Center — Phoenix
California
- Artemis Institute for Clinical Research — Riverside
- Artemis Institute for Clinical Research — San Diego
Connecticut
- CMR of Greater New Haven, LLC — Hamden
Georgia
- North Georgia Clinical Research — Woodstock
Idaho
- Rocky Mountain Clinical Research — Idaho Falls
Illinois
- Northwestern University — Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 131 participants |
| Start Date | 2022-11-14 |
| Est. Completion | 2023-08-01 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05620576
The ClinicalTrials.gov registry entry for NCT05620576 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 131 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eli Lilly and Company, which has 704 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Diabetic Peripheral Neuropathic Pain appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05620576 reports 20 study locations spanning 10 distinct geographic areas — top geographies include Florida, Massachusetts, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05620576 about?
NCT05620576 is a clinical study titled "A Chronic Pain Master Protocol (CPMP): A Study of LY3857210 in Participants With Diabetic Peripheral Neuropathic Pain (NP05).". This study is being done to test the safety and efficacy of the study drug LY3857210 for the treatment of diabetic peripheral neuropathic pain. This trial is part of the chronic pain master protocol H0P-MC-CPMP (NCT05986292) which is a protocol to accelerate the development of new treatments for chr...
What is the current status of trial NCT05620576?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 131 participants. The study started on 2022-11-14. Estimated completion is 2023-08-01.
What conditions does trial NCT05620576 study?
This clinical trial studies the following conditions: Diabetic Peripheral Neuropathic Pain. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05620576?
The interventions under investigation include: Placebo (DRUG), LY3857210 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05620576?
This trial is sponsored by Eli Lilly and Company, which has 704 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05620576 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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