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NCT05860933 · ClinicalTrials.gov registry record · Phase 1
A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy Participants
A Phase 1 study, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
NCT05860933: Completed Phase 1 study, sponsored by Eli Lilly and Company.
NCT05860933 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05860933, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
Study Summary
The main purpose of this study is to evaluate the effect of itraconazole and carbamazepine on LY3537982 when administered as multiple doses by conducting the blood tests to measure how much LY3537982 is in the bloodstream and how the body handles and eliminates LY3537982 in adult healthy participants. The study will also evaluate the safety and tolerability of LY3537982. The study is conducted in two parts. Participants will stay in the research center during the study, which will last about 11 and 15 days for part 1 and part 2, respectively, not including screening.
Primary Outcome
PK: Cmax of LY3537982 administered with or without itraconazole
Interventions
- DRUG Itraconazole
- DRUG LY3537982
- DRUG Carbamazepine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2023-05-08 |
| Est. Completion | 2023-08-28 |
| Phase | Phase 1 |
What the finished NCT05860933 record still lists
NCT05860933 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).
The record links to 0 conditions, and to 3 interventions - of which Itraconazole is the first listed.
NCT05860933 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05860933 about?
NCT05860933 is a clinical study titled "A Study of the Effects of Itraconazole or Carbamazepine on LY3537982 in Healthy Participants". The main purpose of this study is to evaluate the effect of itraconazole and carbamazepine on LY3537982 when administered as multiple doses by conducting the blood tests to measure how much LY3537982 is in the bloodstream and how the body handles and eliminates LY3537982 in adult healthy participant...
What is the current status of trial NCT05860933?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2023-05-08. Estimated completion is 2023-08-28.
What interventions are being tested in trial NCT05860933?
The interventions under investigation include: Itraconazole (DRUG), LY3537982 (DRUG), Carbamazepine (DRUG).
Who is sponsoring clinical trial NCT05860933?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05860933's enrollment target sits among peer trials
30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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