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NCT06039826 · ClinicalTrials.gov registry record · Phase 1

A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
46
Enrollment target

NCT06039826: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT06039826 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 46 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (23% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06039826, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
46 participants
Enrollment target

Study Summary

The main purpose of this study is to determine the effect of LY3437943 when administered subcutaneously on the levels of combined oral contraceptive (COC) ethinyl estradiol and drospirenone in the blood stream in postmenopausal female participants who are overweight or obese. The safety and tolerability of LY3437943 when administered with COC will also be evaluated. This study will last up to approximately 29 weeks for each participant.

Primary Outcome

PK: AUC0-24 of Ethinyl Estradiol

Interventions

  • DRUG LY3437943
  • DRUG Drospirenone
  • DRUG Ethinyl Estradiol

Trial Details

FieldValue
Enrollment Target 46 participants
Start Date 2023-09-12
Est. Completion 2024-07-11
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT06039826 record still lists

NCT06039826 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 46 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (23% lower).

The record links to 0 conditions, and to 3 interventions - of which LY3437943 is the first listed.

NCT06039826 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06039826 about?

NCT06039826 is a clinical study titled "A Study of LY3437943 in Postmenopausal Female Participants Who Are Overweight or Obese". The main purpose of this study is to determine the effect of LY3437943 when administered subcutaneously on the levels of combined oral contraceptive (COC) ethinyl estradiol and drospirenone in the blood stream in postmenopausal female participants who are overweight or obese. The safety and tolerabi...

What is the current status of trial NCT06039826?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 46 participants. The study started on 2023-09-12. Estimated completion is 2024-07-11.

What interventions are being tested in trial NCT06039826?

The interventions under investigation include: LY3437943 (DRUG), Drospirenone (DRUG), Ethinyl Estradiol (DRUG).

Who is sponsoring clinical trial NCT06039826?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06039826's enrollment target sits among peer trials

46 1058th of 2000 higher than 935 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06039826, the US trial registry maintained by the National Library of Medicine. NCT06039826 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.