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NCT05749848 · ClinicalTrials.gov registry record · Phase 1
A Study of Carbon-14-Labelled [14C] LY3372689 in Healthy Male Participants
A Phase 1 study, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 1
- Development phase
- 8
- Enrollment target
NCT05749848: Completed Phase 1 study, sponsored by Eli Lilly and Company.
NCT05749848 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 8 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05749848, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 8 participants
- Enrollment target
Study Summary
The main purpose of this study is to evaluate how much of the study drug (LY3372689), administered as a single dose that has the radioactive substance 14C incorporated into it, passes from blood into urine, feces and expired air in healthy male participants. The study will also measure how much of the study drug gets into the bloodstream, how its broken down, and how long it takes the body to get rid of it. The study will last about 4 weeks. Screening is required within 28 days prior to the start of the study and follow up is required approximately 7 days after discharge.
Primary Outcome
Urinary Excretion of LY3372689 Radioactivity Over Time Expressed as a Percentage of the Total Radioactive Dose Administered
Interventions
- DRUG [¹⁴C]-LY3372689
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 8 participants |
| Start Date | 2023-02-24 |
| Est. Completion | 2023-04-18 |
| Phase | Phase 1 |
What the finished NCT05749848 record still lists
NCT05749848 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 8 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (87% lower).
The record links to 0 conditions, and to 1 intervention - of which [¹⁴C]-LY3372689 is the first listed.
NCT05749848 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05749848 about?
NCT05749848 is a clinical study titled "A Study of Carbon-14-Labelled [14C] LY3372689 in Healthy Male Participants". The main purpose of this study is to evaluate how much of the study drug (LY3372689), administered as a single dose that has the radioactive substance 14C incorporated into it, passes from blood into urine, feces and expired air in healthy male participants. The study will also measure how much of t...
What is the current status of trial NCT05749848?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 8 participants. The study started on 2023-02-24. Estimated completion is 2023-04-18.
What interventions are being tested in trial NCT05749848?
The interventions under investigation include: [¹⁴C]-LY3372689 (DRUG).
Who is sponsoring clinical trial NCT05749848?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05749848's enrollment target sits among peer trials
8 1959th of 2000 higher than 29 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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