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NCT05582096 · ClinicalTrials.gov registry record · Phase 1
A Study of LY3457263 in Obese Participants
A Phase 1 study, sponsored by Eli Lilly and Company.
- Completed
- Registry status
- Phase 1
- Development phase
- 38
- Enrollment target
NCT05582096: Completed Phase 1 study, sponsored by Eli Lilly and Company.
NCT05582096 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 38 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05582096, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 38 participants
- Enrollment target
Study Summary
The main purpose of this study is to evaluate the safety and tolerability of LY3457263 when administered in combination with tirzepatitide in overweight or obese participants. The study will also evaluate how much of LY3457263 gets into the blood stream and how long it takes the body to remove it in overweight or obese participants. The study will last up to approximately 11 weeks.
Primary Outcome
A summary of TEAEs, SAEs and other non-serious adverse events (AEs), regardless of causality, will be reported in the Reported Adverse Events module
Interventions
- DRUG Placebo
- DRUG Tirzepatide
- DRUG LY3457263
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2022-11-11 |
| Est. Completion | 2023-06-08 |
| Phase | Phase 1 |
What the finished NCT05582096 record still lists
NCT05582096 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (37% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT05582096 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT05582096 about?
NCT05582096 is a clinical study titled "A Study of LY3457263 in Obese Participants". The main purpose of this study is to evaluate the safety and tolerability of LY3457263 when administered in combination with tirzepatitide in overweight or obese participants. The study will also evaluate how much of LY3457263 gets into the blood stream and how long it takes the body to remove it in...
What is the current status of trial NCT05582096?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 38 participants. The study started on 2022-11-11. Estimated completion is 2023-06-08.
What interventions are being tested in trial NCT05582096?
The interventions under investigation include: Placebo (DRUG), Tirzepatide (DRUG), LY3457263 (DRUG).
Who is sponsoring clinical trial NCT05582096?
This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT05582096's enrollment target sits among peer trials
38 1197th of 2000 higher than 797 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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