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NCT05916560 · ClinicalTrials.gov registry record · Phase 1

A Study of LY3437943 in Participants With Impaired and Normal Liver Function

A Phase 1 study of Healthy and Hepatic Insufficiency, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
43
Enrollment target
5
Study locations

NCT05916560 is a Phase 1 study of Healthy and Hepatic Insufficiency that has completed, run by Eli Lilly and Company. The registered enrollment target is 43 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (93% lower). The trial reports 5 study locations across 3 states.

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The verdict

NCT05916560, a Phase 1 study of Healthy and Hepatic Insufficiency, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
43 participants
Enrollment target
5
Study locations

Study Summary

The main purpose of this study is to measure how much of LY3437943 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to healthy participants with normal liver function. The safety and tolerability of LY3437943 will also be evaluated. The study may last up to 9 weeks for each participant including the screening period.

Interventions

  • DRUG LY3437943

Study Locations (5)

Florida

  • Accel Research Sites- Clinical Research Unit - DeLand
  • Advanced Pharma Clinical Research - Miami

Texas

  • American Research Corporation at Texas Liver Institute - San Antonio
  • Pinnacle Clinical Research - San Antonio

Arizona

  • Arizona Clinical Trials - Chandler - Chandler

Trial Details

FieldValue
Enrollment Target 43 participants
Start Date 2023-07-13
Est. Completion 2025-03-02
Phase Phase 1

Sponsor

Eli Lilly and Company

1,341 total trials

What the Registry Record Tells You About NCT05916560

The ClinicalTrials.gov registry entry for NCT05916560 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 43 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (93% lower). The listed sponsor is Eli Lilly and Company, which has 1,341 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which LY3437943 is the first listed.

NCT05916560 reports 5 study locations spanning 3 distinct geographic areas - top geographies include Florida, Texas, Arizona.

Frequently Asked Questions

What is clinical trial NCT05916560 about?

NCT05916560 is a clinical study titled "A Study of LY3437943 in Participants With Impaired and Normal Liver Function". The main purpose of this study is to measure how much of LY3437943 gets into the bloodstream and how long it takes the body to eliminate it in participants with mild, moderate and severe impaired liver function compared to healthy participants with normal liver function. The safety and tolerability ...

What is the current status of trial NCT05916560?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 43 participants. The study started on 2023-07-13. Estimated completion is 2025-03-02.

What conditions does trial NCT05916560 study?

This clinical trial studies the following conditions: Healthy, Hepatic Insufficiency.

What interventions are being tested in trial NCT05916560?

The interventions under investigation include: LY3437943 (DRUG).

Who is sponsoring clinical trial NCT05916560?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05916560 being conducted?

This trial has 5 study locations across Arizona, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.