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NCT05959096 · ClinicalTrials.gov registry record · Phase 1

A Study of LY3437943 in Healthy Participants With a High Body Mass Index

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
85
Enrollment target

NCT05959096: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT05959096 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 85 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05959096, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
85 participants
Enrollment target

Study Summary

The study is conducted in two parts (Part A and B). The main purpose of this study is to look at the amount of the LY3437943 that gets into the blood stream and how long it takes the body to get rid of it when given subcutaneously (SC, under the skin) in the upper arm and thigh compared to the abdomen in healthy participants with high body mass index (BMI) in Part A. In Part B, the participants receive LY3437943 intravenously (IV, through a vein) where the safety and tolerability of LY3437943 are evaluated and information about any side effects experienced will be collected. For each participant, the total duration of the study will be approximately up to 157 days and 99 days for Part A and Part B, respectively.

Primary Outcome

Part A: PK: AUC(0-∞) of LY3437943

Interventions

  • DRUG LY3437943

Trial Details

FieldValue
Enrollment Target 85 participants
Start Date 2023-07-18
Est. Completion 2024-07-25
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT05959096 record still lists

NCT05959096 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 85 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (42% higher).

The record links to 0 conditions, and to 1 intervention - of which LY3437943 is the first listed.

NCT05959096 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05959096 about?

NCT05959096 is a clinical study titled "A Study of LY3437943 in Healthy Participants With a High Body Mass Index". The study is conducted in two parts (Part A and B). The main purpose of this study is to look at the amount of the LY3437943 that gets into the blood stream and how long it takes the body to get rid of it when given subcutaneously (SC, under the skin) in the upper arm and thigh compared to the abdom...

What is the current status of trial NCT05959096?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 85 participants. The study started on 2023-07-18. Estimated completion is 2024-07-25.

What interventions are being tested in trial NCT05959096?

The interventions under investigation include: LY3437943 (DRUG).

Who is sponsoring clinical trial NCT05959096?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05959096's enrollment target sits among peer trials

85 656th of 2000 higher than 1,342 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05959096, the US trial registry maintained by the National Library of Medicine. NCT05959096 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.