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NCT05901311 · ClinicalTrials.gov registry record · Phase 1

A Study of [14C]-LY3537982 in Healthy Participants

A Phase 1 study, sponsored by Eli Lilly and Company.

Completed
Registry status
Phase 1
Development phase
16
Enrollment target

NCT05901311: Completed Phase 1 study, sponsored by Eli Lilly and Company.

NCT05901311 is a Phase 1 study that has completed, run by Eli Lilly and Company. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT05901311, a Phase 1 study, has completed, sponsored by Eli Lilly and Company.

COMPLETED
Registry status
Phase 1
Development phase
16 participants
Enrollment target

Study Summary

The main purpose of this study is to conduct blood tests to measure how much LY3537982 is in the bloodstream and how the body handles and eliminates LY3537982 in healthy participants. This study will involve a single dose of 14C radiolabeled LY3537982. This means that a radioactive tracer substance, C14, will be incorporated into the study drug LY3537982 to investigate the study drug and its breakdown products and to find out how much of these passes from blood into urine, feces and expired air. The study will also evaluate the safety and tolerability of LY3537982. The study will be conducted in two parts. The study will last up to 71 days and 61 days for part 1 and 2, respectively.

Primary Outcome

PK: Feur

Interventions

  • DRUG LY3537982
  • DRUG [¹⁴C]-LY3537982

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2023-06-05
Est. Completion 2023-08-10
Phase Phase 1
Eli Lilly and Company

1,341 total trials

What the finished NCT05901311 record still lists

NCT05901311 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).

The record links to 0 conditions, and to 2 interventions - of which LY3537982 is the first listed.

NCT05901311 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT05901311 about?

NCT05901311 is a clinical study titled "A Study of [14C]-LY3537982 in Healthy Participants". The main purpose of this study is to conduct blood tests to measure how much LY3537982 is in the bloodstream and how the body handles and eliminates LY3537982 in healthy participants. This study will involve a single dose of 14C radiolabeled LY3537982. This means that a radioactive tracer substance,...

What is the current status of trial NCT05901311?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2023-06-05. Estimated completion is 2023-08-10.

What interventions are being tested in trial NCT05901311?

The interventions under investigation include: LY3537982 (DRUG), [¹⁴C]-LY3537982 (DRUG).

Who is sponsoring clinical trial NCT05901311?

This trial is sponsored by Eli Lilly and Company, which has 1,341 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT05901311's enrollment target sits among peer trials

16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT05901311, the US trial registry maintained by the National Library of Medicine. NCT05901311 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.