Brigham and Women's Hospital

937 total trials 145 currently recruiting 608 completed

Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 12 trials.

Trial Pipeline

937 total, page 4 of 19

ACTIVE NOT RECRUITING

INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)

NCT07417618

ACTIVE NOT RECRUITING

Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)

NCT07390110

ACTIVE NOT RECRUITING Phase 2

Photobiomodulation for the Prevention of Oral Mucositis

NCT07290413

ACTIVE NOT RECRUITING NA

A Trial of Academic Detailing to Promote Prescribing of Biosimilars

NCT07221890

ACTIVE NOT RECRUITING

Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Target Trial

NCT07255482

ACTIVE NOT RECRUITING

Emulation of the PALOMA-2 Trial

NCT07178743

ACTIVE NOT RECRUITING NA

Trial of Pistachio Consumption in Older Adults

NCT06992544

ACTIVE NOT RECRUITING

Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction

NCT06980623

ACTIVE NOT RECRUITING

Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

NCT06779929

ACTIVE NOT RECRUITING NA

Better Understanding Patient Perspectives of an Educational Tool for Postpartum Hypertensive Patients

NCT06996496

ACTIVE NOT RECRUITING Early Phase 1

Testing a Transdiagnostic TMS Treatment Target

NCT06282146

ACTIVE NOT RECRUITING Phase 4

PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic Hormone-sensitive Prostate Cancer

NCT06479187

ACTIVE NOT RECRUITING NA

Skilled Nursing Facility Care at Home

NCT06416670

ACTIVE NOT RECRUITING

fMRI in CardiaC arrEst With Uncertain Prognosis

NCT06423768

ACTIVE NOT RECRUITING NA

Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees

NCT06391697

ACTIVE NOT RECRUITING NA

Time-limited Trials in the Emergency Department

NCT06378151

ACTIVE NOT RECRUITING NA

Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits

NCT06004700

ACTIVE NOT RECRUITING NA

Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension

NCT05925569

ACTIVE NOT RECRUITING Phase 4

Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45

NCT06173661

ACTIVE NOT RECRUITING NA

Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity

NCT05713071

ACTIVE NOT RECRUITING NA

Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application

NCT05991492

ACTIVE NOT RECRUITING NA

Pathophysiology of Dysautonomia and Postural Tachycardia Syndrome (POTS) in Post-viral Syndromes and COVID-19

NCT07405515

ACTIVE NOT RECRUITING NA

A Positive Psychology Based Intervention (PATH-C) for Caregivers of HSCT Survivors

NCT06153797

ACTIVE NOT RECRUITING Phase 1

Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)

NCT04870125

ACTIVE NOT RECRUITING Phase 1

CP101 for the Treatment of Ulcerative Colitis

NCT05852574

ACTIVE NOT RECRUITING Phase 2

Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease

NCT05575037

ACTIVE NOT RECRUITING Phase 2

Individualized Functional Connectivity Targeting in aiTBS for Depression

NCT05680727

ACTIVE NOT RECRUITING NA

Knee Arthroplasty Activity Trial

NCT04107649

ACTIVE NOT RECRUITING NA

Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity

NCT05715463

ACTIVE NOT RECRUITING NA

Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure

NCT05690464

ACTIVE NOT RECRUITING Phase 2

Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)

NCT04895306

ACTIVE NOT RECRUITING NA

Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0

NCT05553925

ACTIVE NOT RECRUITING NA

Monounsaturated Fatty Acid Supplementation for Overweight and Obese Individuals With Prediabetes

NCT05560971

ACTIVE NOT RECRUITING NA

Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening

NCT05975736

ACTIVE NOT RECRUITING NA

A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor

NCT04796285

ACTIVE NOT RECRUITING NA

Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms

NCT05276739

ACTIVE NOT RECRUITING

AMP SCZ® Observational Study: PREDICT-DPACC

NCT05905003

ACTIVE NOT RECRUITING

Kinematics of Ewing Amputees

NCT06371209

ACTIVE NOT RECRUITING

Birth Control to Improve Birth Spacing

NCT05240066

ACTIVE NOT RECRUITING Phase 4

MR Antagonist and LSD1

NCT04840342

ACTIVE NOT RECRUITING NA

Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C

NCT03482986

ACTIVE NOT RECRUITING Phase 1

Sirtuin-NAD Activator in Alzheimer's Disease

NCT05040321

ACTIVE NOT RECRUITING NA

Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management

NCT05088759

ACTIVE NOT RECRUITING Phase 2

Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases

NCT04899908

ACTIVE NOT RECRUITING Phase 1

Feasibility of [11C]Acetate-PET in LAM and TSC

NCT05467397

ACTIVE NOT RECRUITING

Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study

NCT05220917

ACTIVE NOT RECRUITING

Role of Dietary Habits in Efficacy of Bariatric Surgery - Study B

NCT03467906

ACTIVE NOT RECRUITING NA

COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance

NCT05232669

ACTIVE NOT RECRUITING NA

A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)

NCT04820036

ACTIVE NOT RECRUITING NA

Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water

NCT04567108

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Phase Distribution

PhaseTrial count
Phase 1 90
Phase 2 107
Phase 3 47
Phase 4 77

What the Pipeline for Brigham and Women's Hospital Shows

According to the ClinicalTrials.gov registry, Brigham and Women's Hospital is linked to 937 US clinical trials across every stage of research activity. Of those, 145 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 608 are already marked complete, representing roughly 65% of the total.

The phase mix for Brigham and Women's Hospital reports 124 late-stage studies (Phase 3 and Phase 4 combined) and 197 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Brigham and Women's Hospital is Hypertension with 12 linked trials, and 9 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.