Brigham and Women's Hospital
Open enrollment with an early-phase pipeline tilt
According to ClinicalTrials.gov-derived indexes, Brigham and Women's Hospital sits in the top decile of US sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count).
Brigham and Women's Hospital: 937 sponsored US clinical trials, 145 recruiting.
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Type 2 Diabetes, with 13 trials.
Top-decile sponsor footprint
Brigham and Women's Hospital ranks in the top decile of sponsors by registered trial count (#35 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.
Trial completion reliability score
608 of 677 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (89.8%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.
Open and recent trials
937 total, page 4 of 19
INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)
NCT07417618
Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)
NCT07390110
Photobiomodulation for the Prevention of Oral Mucositis
NCT07290413
A Trial of Academic Detailing to Promote Prescribing of Biosimilars
NCT07221890
Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Target Trial
NCT07255482
Emulation of the PALOMA-2 Trial
NCT07178743
Trial of Pistachio Consumption in Older Adults
NCT06992544
Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction
NCT06980623
Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes
NCT06779929
Better Understanding Patient Perspectives of an Educational Tool for Postpartum Hypertensive Patients
NCT06996496
Testing a Transdiagnostic TMS Treatment Target
NCT06282146
PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic Hormone-sensitive Prostate Cancer
NCT06479187
Skilled Nursing Facility Care at Home
NCT06416670
fMRI in CardiaC arrEst With Uncertain Prognosis
NCT06423768
Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees
NCT06391697
Time-limited Trials in the Emergency Department
NCT06378151
Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits
NCT06004700
Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension
NCT05925569
Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
NCT06173661
Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
NCT05713071
Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application
NCT05991492
Pathophysiology of Dysautonomia and Postural Tachycardia Syndrome (POTS) in Post-viral Syndromes and COVID-19
NCT07405515
A Positive Psychology Based Intervention (PATH-C) for Caregivers of HSCT Survivors
NCT06153797
Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)
NCT04870125
CP101 for the Treatment of Ulcerative Colitis
NCT05852574
Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease
NCT05575037
Individualized Functional Connectivity Targeting in aiTBS for Depression
NCT05680727
Knee Arthroplasty Activity Trial
NCT04107649
Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity
NCT05715463
Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure
NCT05690464
Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)
NCT04895306
Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0
NCT05553925
Monounsaturated Fatty Acid Supplementation for Overweight and Obese Individuals With Prediabetes
NCT05560971
Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening
NCT05975736
A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor
NCT04796285
Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms
NCT05276739
AMP SCZ® Observational Study: PREDICT-DPACC
NCT05905003
Kinematics of Ewing Amputees
NCT06371209
Birth Control to Improve Birth Spacing
NCT05240066
MR Antagonist and LSD1
NCT04840342
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C
NCT03482986
Sirtuin-NAD Activator in Alzheimer's Disease
NCT05040321
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management
NCT05088759
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
NCT04899908
Feasibility of [11C]Acetate-PET in LAM and TSC
NCT05467397
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
NCT05220917
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study B
NCT03467906
COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance
NCT05232669
A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)
NCT04820036
Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water
NCT04567108
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What is open in the Brigham and Women's Hospital pipeline
145 recruiting of 937 indexed (15% open); 608 completed (65%).
Phase mix: 124 late (III/IV) vs 197 early (I/II) (early-phase heavy).
Top condition: Type 2 Diabetes (13 trials), 9 others listed.
How open-pipeline share is computed
Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.
Brigham and Women's Hospital: open-pipeline peers nationwide
Peers matched on 937 registered trials and 15% open enrollment, not the therapeutic-area sidebar.
Brigham and Women's Hospital sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.
Sponsors near 937 trials (± recruiting share)
- Columbia University · 958 trials · 18% recruiting
- Hoffmann-La Roche · 909 trials · 8% recruiting
- University of Minnesota · 966 trials · 19% recruiting
- University of California, Los Angeles · 897 trials · 18% recruiting
Sponsors near 15% open enrollment (± trial volume)
- Incyte Corporation · 15% recruiting · 239 trials
- Northwestern University · 15% recruiting · 1,209 trials
- Nationwide Children's Hospital · 15% recruiting · 188 trials
- University of Michigan Rogel Cancer Center · 15% recruiting · 292 trials
Related
What to do with this Brigham and Women's Hospital page
937 registered trials is a research-attention snapshot, not an endorsement of Brigham and Women's Hospital or any single study.
- 145 of Brigham and Women's Hospital's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
- Type 2 Diabetes is the condition Brigham and Women's Hospital studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Type 2 Diabetes trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Brigham and Women's Hospital pipeline card: 937 registered trials from official public datasets.Report a data error.