Brigham and Women's Hospital
Brigham and Women's Hospital sponsors 937 registered US clinical trials on ClinicalTrials.gov, 145 of them currently recruiting, and 608 completed. 124 of these trials are in Phase 3-4 (later-stage) and 197 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hypertension, with 12 trials.
Trial Pipeline
937 total, page 4 of 19
INcreTin-based thERapies for Cardiovascular Event PrevenTion in Patients With and Without ASCVD (INTERCEPT-ASCVD)
NCT07417618
Comparative Effectiveness of Oral Semaglutide vs Sitagliptin Among Individuals With Heart Failure With Preserved Ejection Fraction (STEP-HFpEF DM ORAL)
NCT07390110
Photobiomodulation for the Prevention of Oral Mucositis
NCT07290413
A Trial of Academic Detailing to Promote Prescribing of Biosimilars
NCT07221890
Mortality Benefit of Ultrasound for Thyroid Nodules Identified With PET Imaging: Non-Inferiority Emulated Target Trial
NCT07255482
Emulation of the PALOMA-2 Trial
NCT07178743
Trial of Pistachio Consumption in Older Adults
NCT06992544
Comparative Effectiveness of Tirzepatide vs Semaglutide in Participants With Type 2 Diabetes and Heart Failure With Preserved Ejection Fraction
NCT06980623
Comparative Study of Tirzepatide Versus Dulaglutide (SURPASS CVOT) or Semaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes
NCT06779929
Better Understanding Patient Perspectives of an Educational Tool for Postpartum Hypertensive Patients
NCT06996496
Testing a Transdiagnostic TMS Treatment Target
NCT06282146
PSMAtrack-tracking Changes in PSMA-PET During Initial Therapy for Metastatic Hormone-sensitive Prostate Cancer
NCT06479187
Skilled Nursing Facility Care at Home
NCT06416670
fMRI in CardiaC arrEst With Uncertain Prognosis
NCT06423768
Magnetic Bead Tracking System and eOPRA Implant System With Bionic Prosthesis for Transtibial Amputees
NCT06391697
Time-limited Trials in the Emergency Department
NCT06378151
Improving Virtual Care of Arthritis: Integrating a Smartphone App Into the EHR for Improved Timeliness of Visits
NCT06004700
Electronic Alert to Improve Testing For Primary Aldosteronism in Patients With Hypertension
NCT05925569
Fremanezumab Treatment of Migraine in Women With Menstrual Migraine Ages 18-45
NCT06173661
Evaluation of Bariatric Endoscopic Antral Myotomy (BEAM) as a Treatment for Obesity
NCT05713071
Improving Sleep With a Digital Cognitive Behavioral Therapy for Insomnia Application
NCT05991492
Pathophysiology of Dysautonomia and Postural Tachycardia Syndrome (POTS) in Post-viral Syndromes and COVID-19
NCT07405515
A Positive Psychology Based Intervention (PATH-C) for Caregivers of HSCT Survivors
NCT06153797
Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS)
NCT04870125
CP101 for the Treatment of Ulcerative Colitis
NCT05852574
Mechanisms of Benefit of IL4RA Inhibition in Aspirin-Exacerbated Respiratory Disease
NCT05575037
Individualized Functional Connectivity Targeting in aiTBS for Depression
NCT05680727
Knee Arthroplasty Activity Trial
NCT04107649
Rheumatology-based Adaptive Intervention for Social Determinants and Health Equity
NCT05715463
Effect of Magnesium Supplementation on Elevated Systolic Blood Pressure
NCT05690464
Testosterone Replacement to Alleviate Pain in Postmenopausal Women (TRAPP Trial)
NCT04895306
Partnerships for Reducing Overweight and Obesity with Patient-Centered Strategies 2.0
NCT05553925
Monounsaturated Fatty Acid Supplementation for Overweight and Obese Individuals With Prediabetes
NCT05560971
Searching for Masses and Calcifications at the Same Time in Breast Cancer Screening
NCT05975736
A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor
NCT04796285
Role of Photic and Non-photic Time Cues in Resetting Circadian Rhythms
NCT05276739
AMP SCZ® Observational Study: PREDICT-DPACC
NCT05905003
Kinematics of Ewing Amputees
NCT06371209
Birth Control to Improve Birth Spacing
NCT05240066
MR Antagonist and LSD1
NCT04840342
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study C
NCT03482986
Sirtuin-NAD Activator in Alzheimer's Disease
NCT05040321
Randomized Controlled Trial of Alert-Based Computerized Decision Support for Optimizing Low-Density Lipoprotein Management
NCT05088759
Stereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain Metastases
NCT04899908
Feasibility of [11C]Acetate-PET in LAM and TSC
NCT05467397
Comparative Effectiveness and Safety of Four Second Line Pharmacological Strategies in Type 2 Diabetes Study
NCT05220917
Role of Dietary Habits in Efficacy of Bariatric Surgery - Study B
NCT03467906
COcoa Supplement and Multivitamin Outcomes Study: Effects on Falls and Physical Performance
NCT05232669
A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)
NCT04820036
Health Effects of Substituting Sugary Beverages With Artificially-sweetened Beverages or Water
NCT04567108
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 90 |
| Phase 2 | 107 |
| Phase 3 | 47 |
| Phase 4 | 77 |
Therapeutic Areas
What the Pipeline for Brigham and Women's Hospital Shows
According to the ClinicalTrials.gov registry, Brigham and Women's Hospital is linked to 937 US clinical trials across every stage of research activity. Of those, 145 studies are currently recruiting, about 15% of the sponsor's indexed portfolio, and 608 are already marked complete, representing roughly 65% of the total.
The phase mix for Brigham and Women's Hospital reports 124 late-stage studies (Phase 3 and Phase 4 combined) and 197 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Brigham and Women's Hospital is Hypertension with 12 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.